Navigation Links
Decreased diversity of bacteria microbiome in the gut is associated with risk of colorectal cancer
Date:12/6/2013

Decreased diversity in the microbial community found in the human gut is associated with colorectal cancer, according to a new study published December 6 in the Journal of the National Cancer Institute.

Previous studies suggest a role for the gut microbiota in colorectal cancer (CRC), but comprehensive epidemiological studies comparing samples from case and control subjects that also consider potential confounders and adjust for multiple comparisons inherently involved in microbiome analysis have not been reported.

Jiyoung Ahn, Ph.D., from Department of Population Health at New York University School of Medicine in New York, NY, and colleagues compared samples and data from participants enrolled in a case-control study. DNA was extracted from fecal samples from 47 case subjects and 94 sex- and body mass index-matched control subjects and was sequenced to determine the gut microbial community structure of case vs control subjects. Odds ratios to determine the relationship between gut microbiota of case subjects vs control subjects were calculated using logistic regression analysis after adjusting for age, sex, BMI, race, smoking, and sequencing batch. They found decreased bacterial diversity in the gut was associated with CRC risk.

The authors highlight several trends in abundance of some key bacteria in the fecal samples they analyzed from case and control subjects that contribute to the decreased diversity associated with CRC risk which they report. Case subjects showed decreased levels of Clostridia, which include some bacterial family members that ferment dietary fiber, to butyrate, which is a major colonic metabolite that may inhibit inflammation and carcinogenesis in the colon. Also of note, increased levels of Fusobacterium and Porphyromonas, bacteria related to inflammation in in the mouth and gastrointestinal track was observed for case vs control subjects.

The authors write, "Because of the potentially modifiable
'/>"/>

Contact: Zachary Rathner
Zachary.Rathner@oup.com
919-677-2697
Journal of the National Cancer Institute
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Aging process accompanied by decreased hippocampal synaptophysin
2. Due the Recent Improvement in the Professionals' Database, FreelanceCoach Bounce Rate Has Been Decreased by 42%!
3. New optical metrics can identify patients on fast track to decreased vision
4. hCGTreatments / Diet Doc hCG Diets & Weight Loss Plans Offer Improved hCG Diet Plans Capable of Targeting Stubborn Belly Fat Now Linked With Decreased Bone Density
5. Risk of death has decreased for children initially treated with dialysis for ESKD
6. Women's Excellence in Menopause Now Offering Treatment Options for Decreased Sex Drive near Rochester Hills, Michigan; Natural Therapy Available via Bioidentical Hormones
7. New Solutions for Hot Flashes, Night Sweats, and Decreased Sex Drive Available Now at Women's Excellence in Menopause, Affiliated with Crittenton Hospital Center
8. Survey of clinicians: User satisfaction with electronic health records has decreased since 2010
9. Overdose education, bystander nasal naloxone rescue kits associated with decreased opioid overdose death
10. Limiting neurosurgery residents work hours hasnt decreased complication rates
11. Decreased kidney function leads to decreased cognitive functioning
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/2/2015)... , ... September 02, 2015 , ... Ericson is a ... Education Director for HCPro and Associate Director of Education for the Association for Clinical ... CDI and ICD-10 for CDI Boot Camps. She serves as a CDI subject matter ...
(Date:9/2/2015)... ... ... Every year at this time, students prepare to go back to school. ... the academic workload confronting them. They just don’t have the skills needed to do ... students how to study. , “Bankers bank. Salesmen sell. Teachers teach. The job of ...
(Date:9/2/2015)... City, KS (PRWEB) , ... September 02, 2015 , ... ... opened its newest office in Kansas – its Johnson County location. Amada ... in healthcare. Mike has a registered nurse background and spent over 20 years in ...
(Date:9/2/2015)... North Las Vegas, NV (PRWEB) , ... September ... ... in Las Vegas and Fort Lauderdale, CENTURION SERVICE GROUP is internationally known as ... the largest medical auction house in the world, selling more than 100,000 pieces ...
(Date:9/2/2015)... ... 02, 2015 , ... On September 9, 2015, over 27,000 people from all ... single-company convention to date for the state of Utah. , “We are thrilled with ... states David Stirling, doTERRA CEO. “One of the most exciting elements of our convention ...
Breaking Medicine News(10 mins):Health News:ezDI Names Noted CDI Educator Cheryl Ericson as Company’s Clinical Documentation Manager 2Health News:ezDI Names Noted CDI Educator Cheryl Ericson as Company’s Clinical Documentation Manager 3Health News:ezDI Names Noted CDI Educator Cheryl Ericson as Company’s Clinical Documentation Manager 4Health News:5 Essential Study Tips Every Student Needs for Academic Success but Schools Do Not Teach 2Health News:5 Essential Study Tips Every Student Needs for Academic Success but Schools Do Not Teach 3Health News:Amada Senior Care Expands to Greater Kansas City 2Health News:Over 1800 Lots of Surplus Used Medical Equipment 2Health News:Over 1800 Lots of Surplus Used Medical Equipment 3Health News:doTERRA to Host the Largest Single-Company Convention in the State of Utah 2
... Dec. 1 The Kerlan Jobe Orthopaedic Clinic, a sports ... United States $3 million to settle allegations that it received ... , The settlement resolves allegations ... of stock option grants, donations to the Kerlan Jobe Foundation, ...
... A scientist who broadened the understanding of how we experience ... -- has won the 2010 University of Louisville Grawemeyer Award ... University in Montreal, was selected for the award from among ... of injury but instead in their brain through a pathway ...
... more likely, British study finds , TUESDAY, Dec. 1 (HealthDay ... to deliver a very preterm baby than more affluent women, ... British study shows. , The University of Leicester research team ... the association between economic status and preterm birth. , For ...
... on computed tomography (CT) imaging of changes in tumors ... bevacizumab may have the potential to predict overall survival, ... of JAMA . The addition of ... with improved survival in patients with stage IV colorectal ...
... ... ... largest national HIV non-profit organizations, is changing its name to HealthHIV and launching a new ... promote the organization’s new vision and expanded capabilities and reach. , , , , ,“HealthHIV ...
... With employee benefit choices becoming more complex, a growing ... during open enrollment season, according to a new survey by ... employers who offer these tools believe they lead employees to ... survey, 45 percent of companies offered employees self-service decision tools ...
Cached Medicine News:Health News:Los Angeles' Kerlan Jobe Orthopaedic Clinic Pays $3 Million to Settle Kickback Allegations 2Health News:Scientist Who Helps Explain Pain Wins Grawemeyer Award 2Health News:More Preemies Born Among the Poor 2Health News:Criteria based on CT imaging after chemotherapy may help predict survival 2Health News:National HIV Non-Profit Announces New Name 2Health News:Employers Plan to Increase Use of Self-Service Decision-Making Technology For Open Enrollment, Watson Wyatt Survey Finds 2Health News:Employers Plan to Increase Use of Self-Service Decision-Making Technology For Open Enrollment, Watson Wyatt Survey Finds 3
(Date:9/2/2015)... 2, 2015 Unilife Corporation ("Unilife" or the ... developer, manufacturer and supplier of injectable drug delivery systems, ... of interest, the Company,s Board of Directors has engaged ... of strategic alternatives to maximize shareholder value. ... during the review process may include a possible sale ...
(Date:9/2/2015)... , September 2, 2015 According ... by Product (Digital & Computed Radiography, Ultrasound, Computed & ... PACS) by Application (Oncology, Cardiology, Neurology) - Global Forecast ... to reach USD 2.8 Billion by 2020 growing at ... Br owse 240 Tables and 44 ...
(Date:9/2/2015)... MARLBOROUGH, Mass. , Sept. 2, 2015 Boston ... in the 2015 Morgan Stanley Global Healthcare Conference on September ... Mike Mahoney , chief executive officer, and ... will participate in a 30-minute question and answer session regarding ... a.m. ET. A live webcast of the question ...
Breaking Medicine Technology:Unilife Announces Review of Strategic Alternatives 2Veterinary Imaging Market Worth USD 2.8 Billion by 2020 2Veterinary Imaging Market Worth USD 2.8 Billion by 2020 3Veterinary Imaging Market Worth USD 2.8 Billion by 2020 4Veterinary Imaging Market Worth USD 2.8 Billion by 2020 5Boston Scientific To Participate In 2015 Morgan Stanley Global Healthcare Conference 2
... Clinical Trials of First, Potential Therapy ... -, SOUTH PLAINFIELD, N.J. and BETHESDA, Md., ... Fibrosis Foundation Therapeutics, Inc.,(CFFT), the nonprofit affiliate of ... an existing collaboration to support development,of PTC124, the ...
... July 15 Abeome Corporation, a,Georgia-based biotech ... Cato BioVentures and a collaboration with Cato ... organization. The investment,and collaboration will help support ... Abeome,s proprietary technology vastly improves the ...
Cached Medicine Technology:PTC Therapeutics Announces $25 Million Award From Cystic Fibrosis Foundation Therapeutics for Development of PTC124 2PTC Therapeutics Announces $25 Million Award From Cystic Fibrosis Foundation Therapeutics for Development of PTC124 3PTC Therapeutics Announces $25 Million Award From Cystic Fibrosis Foundation Therapeutics for Development of PTC124 4Abeome and Cato Research to Collaborate on Ovarian Cancer Therapeutic 2
SOLOS Endoscopy shares your commitment to provide every patient with the highest quality care available through our ongoing research and development of advanced surgical instruments and diagnostic so...
SOLOS Endoscopy shares your commitment to provide every patient with the highest quality care available through our ongoing research and development of advanced surgical instruments and diagnostic so...
... AEM Laparoscopic Instruments incorporate a layered design ... shielded and monitored to prevent stray electrosurgical ... caused by insulation failure or capacitive coupling; ... shield built into all AEM Instruments provides ...
... Instruments incorporate a layered design unique in ... monitored to prevent stray electrosurgical burns along ... insulation failure or capacitive coupling; a well-documented ... into all AEM Instruments provides a neutral ...
Medicine Products: