Navigation Links
Decrease in suicide not linked to newer antidepressants
Date:9/29/2010

Many researchers have studied the relationship between the increase in sales of new antidepressants in recent decades and a simultaneous decline in the suicide rate. In a study based on figures from the Nordic countries, researchers at the Norwegian Institute of Public Health found no evidence that increased sales of the new medicines could be linked to a lower suicide rate. The researchers also did not find any relationship between reduced sales of the older and more toxic antidepressants and a reduction in suicide rates.

The suicide rate has been declining since the end of the 1980s in many Western countries, including Norway, Sweden, Denmark and Finland. Around 1990, the new SSRI drugs (selective serotonin reuptake inhibitors) became available on the market. Sales figures for these new antidepressant drugs have increased annually, whereas sales of the older TCA drugs (tricyclic anti-depressants) have declined substantially. TCA drugs are associated with a risk of poisoning with overdose.

In a study recently published in BMC Psychiatry, the researchers gathered data from the Nordic countries about the suicide rate (number of suicides per 100 000 inhabitants) and sales figures for antidepressants, both for SSRIs and TCAs. A total of over 60 000 suicides were included in the study. Scientists have performed a statistical analysis of the relationship between changes in suicide rates and changes in sales figures for both new and older antidepressants in the period 1990-98 in the respective countries. It is during this time period that the increase in sales was greatest and where the greatest drop in suicide rate could be expected.

The main questions asked were:

  • Can a significant increase in sales of SSRIs in any one year be related to a sharp decline in the suicide rate in the same year?
  • Can the decline in sales of TCAs be related to the decrease in the suicide rate?

When the Nordic countries are studied as one group, the study concludes with a negative answer to both questions.

In a previous study by the NIPH (Bramness et al, 2007) a correlation between the increase in sales figures for SSRIs and the decrease in suicide rate in Norway at the beginning of the 1990s was observed and it was suggested that this could be explained by the fact that fewer people used TCAs to commit suicide. In the new Nordic study this correlation can be disregarded when the other countries are included in the analysis. The new study also found that the reduction in TCA sales cannot explain the reduction in suicide rates. The researchers behind the study conclude that the suicide rate is not affected by sales of antidepressants, but by other factors that are little understood and are difficult to measure.


'/>"/>

Contact: Julie Johansen
julie.johansen@fhi.no
Norwegian Institute of Public Health
Source:Eurekalert

Related medicine news :

1. Severe sleep apnea decreases frequency of nightmare recall
2. Bitter melon extract decreased breast cancer cell growth
3. Common osteoporosis drugs are associated with a decrease in risk of breast cancer
4. Another perk of painkillers? Decreased hormone levels may reduce cancer risk
5. CT and MRI scans associated with shorter hospital stays and decreased costs
6. Study shows for first time decrease in mortality associated with physician order entry system
7. Number of Children in Foster Care Decreases but Critical Needs Go Unmet
8. Simple reduction technique decreases radiation dose associated with CT scans of the head
9. Physical therapist-led exercise in patients in ICU improves function and decreases hospital stay
10. Middle-aged men: Could dwindling testosterone levels decrease sleep?
11. Statins decrease risk of clot-related diseases
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/19/2017)... ... August 19, 2017 , ... Yesterday, the President of the United States ... two sides. There are not two sides to hatred, bigotry, discrimination, and a white ... and the NPEIV stands against all forms of such hatred and discrimination in this ...
(Date:8/18/2017)... ... August 19, 2017 , ... Mr. ... presided over the Amazing Thailand Health and Wellness Tourism Showcase 2017 yesterday, which ... Pakprot, Deputy Governor for Tourism Products and Business at TAT said, “Thailand has ...
(Date:8/18/2017)... York, NY (PRWEB) , ... August 18, 2017 ... ... edition of “Vision & Hearing” campaign, advocating for active, healthy lifestyles and highlighting ... resources available for individuals with hearing impairments and shares the latest innovations in ...
(Date:8/18/2017)... , ... August 18, 2017 , ... The Dawn Johnson ... inaugurating a new charity drive to generate community support for efforts to educate the ... cures and treatments for all types of cancer. , Each day in America, ...
(Date:8/18/2017)... ... 2017 , ... MLM Insurance Group, a Miami area provider ... is working to support the Take Stock In Children Foundation during a regional ... The Take Stock In Children Foundation (TSC) offers guidance and assistance to low ...
Breaking Medicine News(10 mins):
(Date:8/15/2017)... Inc. announced today that its fully owned USA ... York City Office in Yonkers, New York ... (TWO 2 ) homecare therapy. This new East Coast location has ... under the company,s DMEPOS accreditation for Home/Durable Medical Equipment Services. ... Advanced Oxygen Therapy Inc. New ...
(Date:8/8/2017)... --   Second-quarter 2017 revenues ... per share from continuing operations ... percent to $110 million ... $161 million Second-quarter 2017 ... increased 8 percent to $0.93 ...
(Date:8/7/2017)... DUBLIN , Aug. 7, 2017  Endo International ... has reached agreements to resolve virtually all known U.S. ... in discussions to resolve the known remaining U.S. claims ... installment payments beginning in the fourth quarter of 2017 ... part of its second quarter 2017 results, the Company ...
Breaking Medicine Technology: