Navigation Links
Decrease in suicide not linked to newer antidepressants
Date:9/29/2010

Many researchers have studied the relationship between the increase in sales of new antidepressants in recent decades and a simultaneous decline in the suicide rate. In a study based on figures from the Nordic countries, researchers at the Norwegian Institute of Public Health found no evidence that increased sales of the new medicines could be linked to a lower suicide rate. The researchers also did not find any relationship between reduced sales of the older and more toxic antidepressants and a reduction in suicide rates.

The suicide rate has been declining since the end of the 1980s in many Western countries, including Norway, Sweden, Denmark and Finland. Around 1990, the new SSRI drugs (selective serotonin reuptake inhibitors) became available on the market. Sales figures for these new antidepressant drugs have increased annually, whereas sales of the older TCA drugs (tricyclic anti-depressants) have declined substantially. TCA drugs are associated with a risk of poisoning with overdose.

In a study recently published in BMC Psychiatry, the researchers gathered data from the Nordic countries about the suicide rate (number of suicides per 100 000 inhabitants) and sales figures for antidepressants, both for SSRIs and TCAs. A total of over 60 000 suicides were included in the study. Scientists have performed a statistical analysis of the relationship between changes in suicide rates and changes in sales figures for both new and older antidepressants in the period 1990-98 in the respective countries. It is during this time period that the increase in sales was greatest and where the greatest drop in suicide rate could be expected.

The main questions asked were:

  • Can a significant increase in sales of SSRIs in any one year be related to a sharp decline in the suicide rate in the same year?
  • Can the decline in sales of TCAs be related to the decrease in the suicide rate?

When the Nordic countries are studied as one group, the study concludes with a negative answer to both questions.

In a previous study by the NIPH (Bramness et al, 2007) a correlation between the increase in sales figures for SSRIs and the decrease in suicide rate in Norway at the beginning of the 1990s was observed and it was suggested that this could be explained by the fact that fewer people used TCAs to commit suicide. In the new Nordic study this correlation can be disregarded when the other countries are included in the analysis. The new study also found that the reduction in TCA sales cannot explain the reduction in suicide rates. The researchers behind the study conclude that the suicide rate is not affected by sales of antidepressants, but by other factors that are little understood and are difficult to measure.


'/>"/>

Contact: Julie Johansen
julie.johansen@fhi.no
Norwegian Institute of Public Health
Source:Eurekalert

Related medicine news :

1. Severe sleep apnea decreases frequency of nightmare recall
2. Bitter melon extract decreased breast cancer cell growth
3. Common osteoporosis drugs are associated with a decrease in risk of breast cancer
4. Another perk of painkillers? Decreased hormone levels may reduce cancer risk
5. CT and MRI scans associated with shorter hospital stays and decreased costs
6. Study shows for first time decrease in mortality associated with physician order entry system
7. Number of Children in Foster Care Decreases but Critical Needs Go Unmet
8. Simple reduction technique decreases radiation dose associated with CT scans of the head
9. Physical therapist-led exercise in patients in ICU improves function and decreases hospital stay
10. Middle-aged men: Could dwindling testosterone levels decrease sleep?
11. Statins decrease risk of clot-related diseases
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/5/2016)... York, New York (PRWEB) , ... February 05, 2016 , ... ... life? The answer may be at the tips of your toes. Foot massage, whether ... as well as pure comfort and relaxation. The American Board of Multiple Specialties ...
(Date:2/5/2016)... ... February 05, 2016 , ... ... franchises from across the country gathered at the La Valencia Hotel in San ... PROSHRED Chicago was named the year’s most outstanding franchise, walking away with ...
(Date:2/5/2016)... ... 05, 2016 , ... Pivot Point Consulting, a leading national ... & Services for HIT Implementation Support & Staffing report with an outstanding score ... by healthcare executives, managers and clinicians representing over 4,500 hospitals and 2,500 clinics. ...
(Date:2/5/2016)... (PRWEB) , ... February 05, 2016 , ... Colorize ... from on one drop zone to the next using Colorize's dynamic moving camera. Colorize ... project. This package includes a 3D slideshow environment with 1 to 5 focus points ...
(Date:2/5/2016)... ... 05, 2016 , ... Calls Blacklist has just been updated by mobile app ... the developer has fixed known bugs within the app. Calls Blacklist allows its users ... not consuming any of their device’s battery power or memory. It provides a powerful ...
Breaking Medicine News(10 mins):
(Date:2/4/2016)... Feb. 4, 2016  SciClone Pharmaceuticals, Inc. (NASDAQ: ... has entered into a settlement agreement with the ... resolving the SEC,s investigation into possible violations of ... terms of the settlement agreement, SciClone has agreed ... disgorgement, pre-judgment interest and a penalty.  This payment ...
(Date:2/4/2016)... -- Global Immunology Market to 2022 - Large ... growth Summary Immune-mediated inflammatory diseases are ... affect 5–7% of western populations. Although they are ... key patient demographics, they are pathophysiologically linked, being ... inappropriate immune response. Generally, disease-modifying anti-rheumatic drugs, a ...
(Date:2/4/2016)...  Aethlon Medical, Inc. (Nasdaq: AEMD ), ... treat life-threatening diseases, today announced results for the ... 2015. --> --> ... our last quarterly call, we strategically advanced pre-clinical ... to establish the Aethlon Hemopurifier® as a leading ...
Breaking Medicine Technology: