Navigation Links
Decongestant Exposure Needs Closer Look

Study says pseudoephedrine for kids under 2 poses toxicity issues because of use patterns

FRIDAY, Dec. 5 (HealthDay News) -- Exposure to the decongestant pseudoephedrine, found in many cough, cold and allergy medicines, appears to be common among children in the United States.

This is especially true among children younger than 2, who have the highest risk for toxicity and for whom safe dosing recommendations are lacking, say researchers at Boston University's Slone Epidemiology Center.

Pseudoephedrine has been linked to deaths and adverse events in young children, but the absolute risks posed to children by this decongestant are difficult to determine, because the number of children exposed to it and typical patterns of use haven't been known, the researchers explained.

They analyzed data from 1999 through 2006 on pseudoephedrine use among 4,267 children, aged birth to 17 years, included in a national telephone survey of medication use in the United States, and found that 4.9 percent of the children took pseudoephedrine in a given week. Use of the decongestant was highest among children younger than 2 years old (8.1 percent).

The researchers found that 16 children (7.5 percent of users) took more than one pseudoephedrine-containing product within the same week, including six children younger than 2. Of the pseudoephedrine products used by children, most were multiple-ingredient liquids (58.9 percent) and multiple-ingredient tablets (24.7 percent). The study also found that 52 children (25 percent of users) took pseudoephedrine for longer than one week, including seven children younger than 2.

The use of pseudoephedrine by children was much lower in 2006 (2.9 percent) than in 1999-2005 (5.2 percent), likely due to a new law that reduced availability of the decongestant, the researchers said.

The study was published in the December issue of Pediatrics.

"Pseudoephedrine exposure, mostly in the form of multiple-ingredient products, is common among U.S. children and needs to be monitored closely because of the potential for this medication to cause harm, particularly to children under 2," concluded lead author Dr. Louis Vernacchio, an assistant professor of epidemiology and pediatrics at Boston University School of Medicine.

More information

MedlinePlus has more about pseudoephedrine.

-- Robert Preidt

SOURCE: Boston University, news release, Dec. 1, 2008

Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Decongestant in OTC Cold Remedies Effective: FDA Panel
2. Acting Surgeon General Announces National Initiatives to Protect Children by Reducing Exposure to Secondhand Smoke
3. Penn School of Medicine receives $2.3 million to study biomarkers of cigarette smoke exposure
4. Teamsters Applaud Passage of Legislation to Protect Workers From Diacetyl Exposure
5. R rating might be unlikely to affect teens exposure to smoking in movies
6. Occupational exposures may be linked to death from autoimmune disease
7. Low Lead Exposures Can Hurt Kidneys
8. Exposure to sunlight may decrease risk of advanced breast cancer by half
9. Firing clay in unvented kilns may be a source of exposure to dioxins
10. VIDEO from Medialink and EcoQuest: New Technology Reduces Exposure to MRSA Staph
11. Fetal Exposure to Arsenic Affects Genes
Post Your Comments:
Related Image:
Decongestant Exposure Needs Closer Look
(Date:11/25/2015)... ... November 25, 2015 , ... The McHenry County law ... successful appellate decision obtained by Attorneys Francisco J. Botto and Alex C. Wimmer. Attorneys ... Workers’ Compensation Comm’n, 2015 IL App (2d) 130884WC. , According to court documents, Adcock ...
(Date:11/25/2015)... ... ... Smiles by Stevens is pleased to announce the addition of ... patients are aware of the benefits of Botox® in the treatment of moderate facial ... discomfort, soreness, and pain as a result of Jaw Tension, TMJ (temporo-mandibular joint) disorder, ...
(Date:11/25/2015)... ... ... Beddit® has launched a new Android app for use with ... more intuitive SleepScore™ that rates sleep quality on a 100-point scale and makes it ... a proprietary algorithm. Beddit analyzes the data to provide an easy to understand scientific ...
(Date:11/25/2015)... ... November 25, 2015 , ... In an ongoing Clinical Study conducted by an ... IL, UV Angel is evaluating the efficacy of its product and its disinfection protocol. ... 30 beds) from May 2014 through October 2015 at a 360-bed, acute-care, academic medical ...
(Date:11/25/2015)... D.C. (PRWEB) , ... November 25, 2015 , ... Today, ... fatalities on our nation’s roadways has dropped below 10,000 for the first time since ... 10,076 in 2013. , According to data released by the National Highway Traffic Safety ...
Breaking Medicine News(10 mins):
(Date:11/25/2015)... announced the issue of United States patent No. 9,192,509  entitled: " Methods ... the company,s AVACEN 100 dry heat therapy medical device and specific methods of use, referred to ... Photo - ... ... ...
(Date:11/25/2015)... , Nov. 25, 2015 USP 800 ... drug preparations (e.g. pharmacists, pharmacy technicians, nurses, physicians, ... technicians). The chapter also covers all entities which ... pharmacies, hospitals, other healthcare institutions, patient treatment clinics, ... --> --> What is ...
(Date:11/25/2015)... , Nov. 25, 2015  Mindray ... (NYSE: MR ), a leading ... devices worldwide, today announced that it ... meeting of shareholders at the Company,s Hong ... Century, 193 Prince Edward West Road, Mongkok ...
Breaking Medicine Technology: