Navigation Links
Decaffeinated coffee preserves memory function by improving brain energy metabolism
Date:2/1/2012

Researchers from Mount Sinai School of Medicine have discovered that decaffeinated coffee may improve brain energy metabolism associated with type 2 diabetes. This brain dysfunction is a known risk factor for dementia and other neurodegenerative disorders like Alzheimer's disease. The research is published online in Nutritional Neuroscience.

A research group led by Giulio Maria Pasinetti, MD, PhD, Professor of Neurology, and Psychiatry, at Mount Sinai School of Medicine, explored whether dietary supplementation with a standardized decaffeinated coffee preparation prior to diabetes onset might improve insulin resistance and glucose utilization in mice with diet-induced type 2 diabetes. The researchers administered the supplement for five months, and evaluated the brain's genetic response in the mice. They found that the brain was able to more effectively metabolize glucose and use it for cellular energy in the brain. Glucose utilization in the brain is reduced in people with type 2 diabetes, which can often result in neurocognitive problems.

"Impaired energy metabolism in the brain is known to be tightly correlated with cognitive decline during aging and in subjects at high risk for developing neurodegenerative disorders," said Dr. Pasinetti. "This is the first evidence showing the potential benefits of decaffeinated coffee preparations for both preventing and treating cognitive decline caused by type 2 diabetes, aging, and/or neurodegenerative disorders."

Coffee intake is not recommended for everybody due to the fact that it is associated with cardiovascular health risks such as elevated blood cholesterol and blood pressure, both of which lead to an increased risk for heart disease, stroke, and premature death. These negative effects have primarily been attributed to the high caffeine content of coffee. Nonetheless, these novel findings are evidence that some of the non-caffeine components in coffee provide health benefits in mice. Dr. Pasinetti hopes to explore the preventive role of decaffeinated coffee delivered as a dietary supplement in humans.

"In light of recent evidence suggesting that cognitive impairment associated with Alzheimer's disease and other age-related neurodegenerative disorders may be traced back to neuropathological conditions initiated several decades before disease onset, developing preventive treatments for such disorders is critical," he said.


'/>"/>

Contact: Mount Sinai Press Office
newsmedia@mssm.edu
212-241-9200
The Mount Sinai Hospital / Mount Sinai School of Medicine
Source:Eurekalert

Related medicine news :

1. Can Coffee Really Thwart Type 2 Diabetes?
2. Why coffee drinking reduces the risk of Type 2 diabetes
3. Study Links Coffee to Lower Risk of Endometrial Cancer
4. Daily Coffee May Lower Your Skin Cancer Risk
5. Lots of Coffee Might Lower Depression Risk: Study
6. Mystery ingredient in coffee boosts protection against Alzheimers disease
7. Coffee drinking improves hepatitis C treatment response
8. Could Coffee Lower Mens Risk for Prostate Cancer?
9. Coffee may reduce risk of lethal prostate cancer in men
10. Are Coffee Drinkers Less Prone to Aggressive Breast Cancer?
11. Coffee reduces breast cancer risk
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/24/2016)... ... May 24, 2016 , ... Eggsurance, the first independent, non-clinic ... its community and education hub for women considering fertility preservation, as well as ... safe and welcoming place for women to find cycle buddies, get clinic recommendations ...
(Date:5/24/2016)... ... May 24, 2016 , ... ... Jonathan (Jon) Otterstatter to its board of directors. Otterstatter is co-founder, ... in the development of technological innovations that lead to broad-based healthcare solutions. , ...
(Date:5/24/2016)... ... May 24, 2016 , ... Bio-Logic Aqua® Research ... forty years and a trainer for Ageless Grace ( http://www.agelessgrace.com ) to discuss ... on May 16, 2016. , Formerly a Northwestern University Literature Professor, Kinst gravitated ...
(Date:5/24/2016)... McLean, VA (PRWEB) , ... May 24, 2016 , ... ... and smarter - with the launch of the Aquanta Water Heater Controller , ... a smart phone or web-enabled device. As the Nest thermostat does for HVAC ...
(Date:5/24/2016)... ... May 24, 2016 , ... Harvard Health Publications, the ... that will deliver a new series of Q&A videos to clinicians and patients ... and expertise of Harvard Medical School faculty into brief videos that clinicians using ...
Breaking Medicine News(10 mins):
(Date:5/24/2016)... May 24, 2016 The ... world , s first dual therapy stent, ...   OrbusNeich, a global company specializing in ... portfolio to include products to treat peripheral artery disease. ... first entry devices for lower limb and arteriovenous (AV) ...
(Date:5/24/2016)... Dutch surgeons have launched a ground-breaking medical app to ... patients on a global scale. Medical professionals from Europe ... and the US have already signed up for the app, ... totally secure environment. Education  "Imagine a doctor ... a surgeon at Harvard to treat a bomb victim via live ...
(Date:5/23/2016)... --Diplomat Pharmacy, Inc. (NYSE: DPLO) announced today the start ... hands-on learning experience is a 12-week summer program, May ... and Internship programs bring participants to ... are provided optional housing free of charge through Diplomat ... Riverfront Residence Hall to foster communication and collaboration among ...
Breaking Medicine Technology: