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'Decade of vaccines' has potential to save lives, but challenges ahead
Date:6/8/2011

iologicals. With new life-saving vaccines available and many more in the pipeline, innovative financing modelsincluding tiered pricing, where low-income countries pay less, and robust purchasing commitments from developing countriesare needed to move vaccines off the shelf and get them to the people who need them most.

Vaccines in the Pipeline

As many as twelve new vaccines may be rolled out in the next decade against diseases such as typhoid, malaria, and dengue. Researchers are at a critical point in vaccine development, but they will need to overcome a number of challenges in the near future. These include securing the financing needed to get potentially life-saving medicines over clinical and regulatory hurdles within the next three to five years.

  • A malaria vaccine candidate is currently undergoing the last phase of human testing before submission to regulators. If it is shown to be safe and effective, the World Health Organization could recommend that countries start using it as early as 2015, say Christian Loucq and coauthors at the PATH Malaria Vaccine Initiative. With the costs to date of developing this vaccine covered, stakeholders now face the challenge of providing an approved vaccine to millions of people in developing countries, the authors say.

  • According to Lewellys Barker and colleagues at Aeras, tuberculosis cases will continue to burden India, China, South Africa, Nigeria, and other countries unless partnerships are successful in overcoming technical obstacles and securing the funding needed to push promising new vaccine candidates through safety and efficacy trials. According to the authors, these partnerships must also foster political will in order to develop and make available new and powerful TB vaccines, an essential part of the strategy to eliminate the disease by 2050.

  • The 1.4 billion people living below the World Bank's poverty levelthe so-called "bottom billion"are in desperat
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Contact: Kay Campbell
kcampbell@burnesscommunications.com
301-652-1558
Burness Communications
Source:Eurekalert

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