Navigation Links
Deaths from pancreatic cancer rise, fall among racial lines
Date:11/12/2013

Pancreatic cancer death rates in whites and blacks have gone in opposite directions over the past several decades in the United States, with the direction reversing in each ethnicity during those years. The finding comes from a new study by American Cancer Society researchers, who say the rising and falling rates are largely unexplainable by known risk factors, and who call for urgent action for a better understanding of the disease in order to curb increasing death rates. The study appears early online in the Journal of the National Cancer Institute.

Cancer of the pancreas remains one of the deadliest cancer types. It is the fourth leading cause of cancer death in the United States, estimated to cause 38,460 deaths in the U.S. in 2013. While mortality from most other major cancers as well as from all cancers combined has been dropping for more than two decades, deaths from pancreatic cancer have been increasing in recent years. Cigarette smoking, obesity, and red and/or processed meat have been linked to the disease, but not much is known about its major causes. Other suspected lifestyle risk factors include low vegetable and fruit intake, physical inactivity, and alcohol consumption.

To better understand the causes and risk factors for pancreatic cancer, researchers led by Jiemin Ma, Ph.D., now affiliated with Brigham and Women's Hospital in Boston examined long-term disease trends in pancreatic cancer death rates in the United States between 1970 and 2009. They found in white men, pancreatic cancer death rates decreased by 0.7% per year from 1970 to 1995, then reversed, increasing by 0.4% per year through 2009 (the latest year for which data was available). Among white women, rates increased slightly from 1970 to 1984, stabilized until the late 1990s, then increased by 0.5% per year through 2009. In contrast, death rates among African Americans increased between 1970 and the late 1980s (women) or early 1990s (men), after which they began to decrease. However, death rates continued to be substantially higher in blacks than in whites in both men and women.

The authors say the difference in mortality trends between blacks and whites are not fully explained by differences in patterns of smoking, widely recognized as the main contributor to decreases in pancreatic cancer death rates. Smoking prevalence has decreased in both blacks and whites since 1965. The authors surmise that other factors may have modified the impacts of smoking on pancreatic cancer, and say further studies on the mechanisms by which smoking causes pancreatic cancer are warranted.

While obesity has been linked with a 20% increased death risk from pancreatic cancer, the lack of an increase in pancreas cancer mortality rates in blacks, among whom obesity is more prevalent, would make obesity alone an unlikely culprit. In addition, improvements in diagnostic techniques may have contributed to increasing incidence and mortality rates among whites by identifying pancreatic cancers that previously went undiagnosed. But a lack of reliable long-term data makes it difficult to evaluate the potential influence of other suspected risk factors, like meat and vegetable intake. The authors say the decreasing mortality trend in African Americans over the past 10 to 15 years is particularly interesting, as the factors that are likely contributing to recent increases in pancreatic cancer deaths in whites (e.g.: obesity, diabetes, and improved diagnosis) have also increased in African Americans.

"This study underscores the need for urgent action on several fronts," said Ahmedin Jemal, DVM PhD, senior author of the paper. "We need to invest more into pancreatic cancer research to understand why this disease is rising or falling in different races. In the meantime, we have to address modifiable risk factors such as obesity and smoking to reduce the future burden of pancreatic cancer in all populations."


'/>"/>

Contact: David Sampson
david.sampson@cancer.org
American Cancer Society
Source:Eurekalert

Related medicine news :

1. Higher-spending hospitals have fewer deaths for emergency patients
2. Reported Decline in U.S. Pneumonia Deaths May Be False: Study
3. Groundbreaking Nigeria summit results in major commitment to reduce child deaths
4. Measles Deaths Falling Worldwide
5. On-the-job deaths steady in Michigan; Number of burn injuries underreported
6. Pneumococcal disease: More cases but fewer deaths
7. Reported increase in older adult fall deaths due to improved coding
8. Inhaled Steroids Lead to Big Drop in Asthma Deaths at Texas Hospital: Study
9. U.S. Assistance to Africa Cut AIDS-Related Deaths: Study
10. Injury-Linked Deaths Vary Widely Among States
11. No Progress in Reducing U.S. Motorcycle Deaths: Report
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/8/2016)... San Francisco, California (PRWEB) , ... December 08, 2016 , ... ... health coaches, has raised an $18M Series B led by Canvas Ventures . ... use the capital to scale its mobile platform to serve more consumers who are ...
(Date:12/8/2016)... , ... December 08, 2016 , ... ... financial planning services from offices headquartered in Hamilton County, is embarking on a ... , LuvFurMutts specializes in finding new homes for orphaned or neglected senior dogs ...
(Date:12/8/2016)... ... December 08, 2016 , ... Peter Zipp Insurance, ... and around the greater Phoenix metropolitan region, is announcing a charity event to ... of the Homeless Youth Connection is to promote community awareness of the ongoing ...
(Date:12/8/2016)... ... December 08, 2016 , ... The Compretta Insurance Agency, ... residential clients in and around the Hancock County area, is announcing the launch of ... Food Pantry. , The Hancock County Food Pantry has worked for more than 30 ...
(Date:12/8/2016)... ... December 08, 2016 , ... ... to families and business owners in and around central Kansas, is joining the ... at-risk youth in the region. , Headquartered in Wichita, Youth Horizons works to ...
Breaking Medicine News(10 mins):
(Date:12/8/2016)... Dec. 8, 2016 Dignitana, a world leader ... with Boa® Technology, creator of the award-winning, patented Boa® ... use with the DigniCap® scalp cooling system. DigniCap® was ... December 2015, and is the first medical scalp cooling ... scalp cooling system features a patented tight-fitting silicone cooling ...
(Date:12/8/2016)... According to a new ... (Actual Sugars, Sugar Alcohols, Artificial Sweeteners), Type (Powder/Granule, ... Formulation (Oral, Topical, Parenteral) - Global Forecast to ... healthy growth during the last decade, and is ... between 2016 and 2021 to reach USD 1,060.6 ...
(Date:12/8/2016)... , Dec. 8, 2016  Hanson Research, an ... dissolution testing and diffusion testing instruments for the ... by Teledyne Instruments, Inc. ("Teledyne"). The move is ... of precision testing instruments, as well as expand ... of new products and services. Logo - ...
Breaking Medicine Technology: