Navigation Links
Deadly stomach infection rising in community settings, Mayo Clinic study finds
Date:10/26/2009

ROCHESTER, Minn. Mayo Clinic researchers have found that a sometimes deadly stomach bug, Clostridium difficile, (http://www.mayoclinic.org/c-difficile/) is on the rise in outpatient settings. Clostridium difficile is a serious bacteria that can cause symptoms ranging from diarrhea to life-threatening inflammation of the colon. These findings were presented today at the 2009 American College of Gastroenterology (ACG) Annual Meeting in San Diego.

Clostridium difficile, often called C. difficile or "C. diff", is a bacterium that is resistant to some antibiotics and is most often contracted by the elderly in hospitals and nursing homes.

"Recent reports have shown increasing incidence and severity of C. difficile infection especially in the older population," says Darrell Pardi, M.D., Mayo Clinic gastroenterologist and senior author on the study. "Our study examines why the cases are on the rise and who is getting the infection."

In this population-based study, researchers studied 385 cases of C. difficile bacterial infection from 1991-2005 to determine how many cases were hospital-acquired versus community-acquired infections. Of the cases, 192 were hospital-acquired and 35 were residents of nursing homes. Of these hospital-acquired cases, the median age of infection was 72 years; in contrast, 158 cases were community-acquired and the median age was 50 years. Thirty-five percent of the hospital infections had a severe illness compared to 22 percent of community infections who had a severe illness.

The patients with community-acquired infection were also less likely than the hospital-acquired group to have been exposed to antibiotics before their infection. Thus, many of the community-acquired infections lacked the traditional risk factors for infection, namely recent hospitalization and exposure to antibiotics.

There were no differences between community- and hospital-acquired infections in terms of what patients were treated with (primarily metronidazole), response rates, or recurrence rates after treatment.

"We are seeing more cases of C. difficile in the community, but they tend to be less severe and in a younger population," says Dr. Pardi. "The growing incidence of C. difficile infection in both inpatient and outpatient settings could be linked to the increasing usage of antibiotics and to the possibility that C. difficile may be getting resistant to some of our newer antibiotics."

There are hundreds of kinds of bacteria found normally in the intestines. Many play beneficial roles in the body. When a patient takes an antibiotic to treat an infection, it often destroys beneficial bacteria as well as the bacteria that are causing the illness. Without enough healthy bacteria, dangerous pathogens such as C. difficile can quickly grow out of control. Once it takes hold, C. difficile can produce two virulent toxins that attack the lining of the intestine.

"Doctors have gotten better at spotting C. difficile in hospitals and nursing homes; however, now doctors and patients need to be more aware that you can get this infection as an outpatient and that a case of diarrhea or abdominal cramps at home could become serious," says Dr. Pardi.

According to the Centers for Disease Control and Prevention, each year in the United States, C. difficile is responsible for tens of thousands of diarrhea cases and at least 5,000 deaths.


'/>"/>

Contact: Amy Tieder
newsbureau@mayo.edu
507-284-5005
Mayo Clinic
Source:Eurekalert

Related medicine news :

1. Scientists Probe Sepsis Deadly Secrets
2. HIV denialists spread misinformation online -- consequences could be deadly; and more
3. Greeks get space-based help in wake of deadly fires
4. Jefferson scientists find protein may be key in developing deadly form of pancreatic cancer
5. Drug combination might offer hope for patients deadly brain tumors
6. MARCOR Responds to Deadly MRSA Outbreak
7. Common virus may help doctors treat deadly brain tumors
8. A new key to detecting deadly aortic aneurysms
9. Genes Unlock New Treatments for Deadly Melanoma
10. Northwestern exposing most deadly infectious diseases in 3-D
11. Research Lacking on Why Heart Disease is More Deadly for Women
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/22/2017)... ... February 22, 2017 , ... In ... reported skipping doses or not filling a prescription because they could not afford ... cost-related problems getting medications were 30-60%*. At the same time, hospitals, ...
(Date:2/22/2017)... , ... February 22, 2017 , ... Using the power ... utilizing a simple online checklist. Over a period of just 24 months, thousands of ... of an online checklist called T.A.D. , “The internet is not getting quieter. In ...
(Date:2/22/2017)... TX (PRWEB) , ... February 22, 2017 , ... ... the launch of ProGen™ PRP, the latest innovation in the delivery of Platelet ... wound care, aesthetics, cardiovascular and pain management, to accelerate tissue synthesis and provide ...
(Date:2/22/2017)... ... ... Super-Sod will attend the Athens Home Show with a brand new look during ... simple Athens Home Show booth of 2016, this year’s exhibit space includes recycled display ... constructed furniture from recycled pallet wood at the Super-Sod farm in Fort Valley, Georgia. ...
(Date:2/22/2017)... ... February 22, 2017 , ... ... with so many different solutions on the market, it is easy to start ... Texas Premier Locksmith offers a complimentary security consultation. , Home Security Hardware ...
Breaking Medicine News(10 mins):
(Date:2/22/2017)... PORTLAND, Oregon and PUNE, India , February 22, 2017 ... that the global market was valued at $3,453 million in 2015 and is projected ... to 2022. The arthroscopic implants segment held nearly two-fifths of the total market in ... ... Allied Market Research Logo ...
(Date:2/22/2017)... , Feb. 22, 2017   Protein Sciences ... of Flublok® Influenza Vaccine , announced today that ... for Influenza Vaccine Introduction (PIVI) and the Mongolian Ministry ... impacts of the flu.  The doses of Flublok have ... Mongolia for health care workers, pregnant ...
(Date:2/22/2017)... Pharma announced today the completion of its executive management ... were added to form an executive team that will ... the implementation and administration of its newly executed strategic ... companies. Effective as of February ... following eight members reporting to Robert DiCrisci : ...
Breaking Medicine Technology: