Navigation Links
Database Helps Assess Your Breast Cancer Risk

Lifestyle factors and environmental hazards are included in the searchable site,,,,

SUNDAY, Jan. 25 (HealthDay News) -- If you want to learn more about the key risk factors for breast cancer, such as obesity, pollutants or smoking, a database can guide you to the available evidence that confirms or quells an association.

"Breast cancer is multifactorial. It would be rare for there to be a single environmental chemical that alone would be sufficient to cause an increase in breast cancer," said Dr. Robert Schneider, co-director of breast cancer research at New York University School of Medicine in New York City.

"In many cases, an increased risk of breast cancer is quite small, and we don't yet know how each factor affects the risk of breast cancer," he said, explaining that it's similar to a puzzle. "We need to know how all of the pieces fit together, and this database begins to help us start assessing some of that."

The database, a joint project of Susan G. Komen for the Cure and the Environmental Factors and Breast Cancer Science Review project led by the Silent Spring Institute, includes information on 216 chemicals, diet, smoking, physical activity and weight that may play a role in the development of breast cancer.

Fewer than 100 chemical compounds have been identified as human carcinogens by the International Agency of Research on Cancer. However, that doesn't mean that all other chemicals are safe, just that they haven't been tested. And, an estimated 80,000 chemicals have been registered for commercial use in the United States, according to the database study, which was published in a recent issue of the journal Cancer.

Although many factors have been associated with breast cancer, Schneider said his top three would include the chemical bisphenol A, radiation exposure from CT scans and delayed first pregnancy.

Bisphenol A (BPA) is an estrogenic chemical found in many products made of polycarbonate plastic (clear, hard plastic), such as baby bottles, reusable water bottles, food storage containers, food cans and water supply pipes, according to the National Institute of Environmental Health Sciences. Although no human studies have confirmed an association with breast cancer, a study done in mice suggests there may be a link. However, the U.S Food and Drug Administration recently said the agency felt there were "adequate margins of safety" for the chemical in the amounts commonly consumed.

"We don't know what constitutes an unacceptable level," said Schneider who would prefer to err on the side of caution and limit BPA exposure, especially in infants and young girls.

Schneider said another concerning risk factor is the amount of radiation people are exposed to for routine health problems, particularly from CT scans.

Although the last risk factor from Schneider's top three -- delayed first pregnancy -- isn't one people are likely to change, he said it's important to be aware of it. "In a modern society, it's exceedingly difficult to have a pregnancy before 20 when it would be quite protective," said Schneider.

Dr. Jay Brooks is chair of hematology/oncology at Ochsner Health System in Baton Rouge, La. He said, "When you look at environmental and chemical risk factors, you have to remember that we live in a sea of chemicals, and those chemicals have made our lives so much nicer, and it's hard to know exactly what each one does to an individual's risk.

"I advise my patients to try to control the things you have good control over. Weight is a huge issue in breast cancer, as is the use of combined estrogen/progesterone after menopause," he added.

Brooks said extra weight is a risk factor that many women underestimate, but being overweight clearly increases risk. And, he said, estrogen therapy alone used to ease menopausal symptoms doesn't seem to increase risk the way the estrogen/progesterone combination does.

More information

To learn more about breast cancer risk factors, check the searchable database from the Silent Spring Institute.

SOURCES: Robert Schneider, Ph.D., co-director, cancer research, New York University School of Medicine, New York City; Jay Brooks, M.D., chair, hematology/oncology, Ochsner Health System, Baton Rouge, La.

Copyright©2009 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. BNC Technologies Selects Raima Database Manager Embedded
2. Blackbaud to Deliver National CRM Database and Bilingual Website for The Kidney Foundation of Canada
3. Chicago Neurosurgeon, in Castle Connolly Top Doctor Database, Being Considered for U.S. Surgeon General
4. Lexi-Comp Databases Now Available for the iPhone™ and iPod touch
5. Best Practice Database Adds Research Highlighting Effective Tactics of Sales Force and Manufacturing Groups in the Pharmaceutical Industry
6. Best Practice Database Provides Key Findings for Biopharma Product Launch Evaluation
7. Best Practice Database Provides Benchmarks for Fixed-Dose Combination (FDC) Drug Development
8. Birdstep Technology Adds Micro HTTP Server to the Upcoming Release of its Raima Database Manager, RDM Embedded Version 9.0
9. Birdstep Technology Adds ENEA's OSE RTOS to the List of Operating Systems Supported by Their RDM Server, Embedded Database Product
10. U-M to house leading drug database
11. Quantros Launches Patient Safety Organization Manager to Streamline PSO Data Management and Submission to the Network of Patient Safety Databases
Post Your Comments:
(Date:11/25/2015)... BROOK, Ill. (PRWEB) , ... November 25, 2015 ... ... larger and potentially more aggressive than those found on mammography, according to a ... MRI findings of additional cancers not seen on mammography may necessitate a change ...
(Date:11/25/2015)... ... 2015 , ... As part of a global movement to ... together who want to combine talents and resources to help create sustainable communities ... The non-profit launched its first major fundraiser on November 6, 2015 at Bent ...
(Date:11/25/2015)... ... November 25, 2015 , ... The holiday season ... and pleasing the palates of attendees is of the utmost importance. Whether you ... seasonal get-together, give these recipes a try this holiday season. , Turkey Croquettes ...
(Date:11/25/2015)... ... November 25, 2015 , ... Finnleo, a leader in ... on several models of traditional and far-infrared saunas. , For traditional saunas, ... the most traditional Finnish sauna wood, and Finnleo uses only European Grade A Nordic ...
(Date:11/25/2015)... , ... November 25, 2015 , ... ... has been recognized once again for its stellar workplace culture with the company’s ... , Medical Solutions’ Cincinnati office was named a finalist in Cincinnati ...
Breaking Medicine News(10 mins):
(Date:11/25/2015)... Nov. 25, 2015 Allergan plc (NYSE: ... and Rugen Therapeutics, a start-up  biotechnology company focused ... CNS disorders and funded by the F-Prime Biomedical ... entered into an exclusive collaboration to support the ... Spectrum Disorders (ASD) and Obsessive Compulsive disorders (OCD). ...
(Date:11/25/2015)... 25, 2015 USP 800 applies to ... (e.g. pharmacists, pharmacy technicians, nurses, physicians, physician assistants, ... chapter also covers all entities which store, prepare, ... other healthcare institutions, patient treatment clinics, physicians, practice ... --> What is the purpose ...
(Date:11/25/2015)... Asia -based venture ... and the New Investors will make a direct equity ... private placement. The financing will help IOPtima to continue ... in the treatment of glaucoma, as well as to ... system with the U.S. Food and Drug Administration, commencing ...
Breaking Medicine Technology: