Navigation Links
Data from Pooled Analyses Demonstrates Welchol, Combined with Metformin- or Sulfonylurea-Based Therapy, Significantly Lowers Blood Glucose in Adults with Type 2 Diabetes
Date:5/16/2008

First and Only Therapy Approved to Treat Both Type 2 Diabetes and High LDL-

Cholesterol

Welchol Recently Added to ACE/AACE Road Maps

PARSIPPANY, N.J., May 16 /PRNewswire/ -- Daiichi Sankyo, Inc. (DSI) announced today that data from two pooled analyses further demonstrate that Welchol(TM) (colesevelam HCl), in combination with metformin- or sulfonylurea- based therapy, significantly lowers blood glucose (as measured by A1C) in patients with type 2 diabetes mellitus who had failed to achieve glycemic control (ADA target of A1C <7%). These findings, presented at the American Association of Clinical Endocrinologists' (AACE) 17th Annual Meeting and Clinical Congress, are the latest in a series of diabetes-related milestones for Welchol. In April, DSI announced that Welchol was added to the American College of Endocrinology (ACE)/AACE "Road Maps to Achieve Glycemic Control in Type 2 Diabetes Mellitus."

The efficacy of Welchol compared to placebo was evaluated in patients receiving metformin-based or sulfonylurea-based therapy (either monotherapy or in combination with other antidiabetes therapy) in two separate pooled analyses of patients from three Welchol pivotal studies.* The addition of Welchol in patients on established metformin-based therapy demonstrated a significant mean A1C reduction of 0.50%, placebo-corrected change from baseline (mean baseline A1C was 8.2% for both Welchol and placebo). In a second pooled analysis, the addition of Welchol in patients on established sulfonylurea-based therapy demonstrated a mean reduction in A1C of 0.53%, placebo-corrected change from baseline (mean baseline A1C was 8.2% and 8.3% for Welchol and placebo, respectively).

"These analyses further demonstrate the potential benefit of adding Welchol to current common diabetes treatment regimens," said Vivian E. Fonseca, Professor of Medicine and Pharmacology and Chief, Section of Endocrinology, Tulane Univer
'/>"/>

SOURCE Daiichi Sankyo, Inc.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7

Related medicine news :

1. New Analyses of long-term LIALDA (mesalamine) data presented at ACG
2. Investigational Agent Targeting Metabotropic Glutamate 2/3 Receptors Demonstrates Antipsychotic Activity in Humans, Study in Nature Medicine Finds
3. Study Demonstrates Marteks Algal DHA Oil Improves Blood Triglyceride Lipid Levels
4. Highmarks Hospital Pay-for-Performance Program Demonstrates Impressive Results
5. Facet Solutions AFRS(TM) Implant Demonstrates Positive Clinical Results After One Year Follow Up
6. LIALDA demonstrates prolonged release of mesalamine in an in vitro study using a simulated colon
7. ENDEAVOR IV achieves primary endpoint, demonstrates similar safety profile compared to Taxus stent
8. New Study Data Published in British Journal of Urology Demonstrates Cryoablation Effective for Kidney Cancer
9. Data Show SuperGens Multi-Targeted Tyrosine Kinase Inhibitor Demonstrates Pre-clinical Activity in Glioblastoma Multiforme
10. First in the World Live Case Using New Technology Demonstrates Shorter Procedure Time
11. Study Shows Organons Asenapine Demonstrates Efficacy and Tolerability in Treating Acute Schizophrenia
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/1/2014)... study published today in the Journal of the ... than 50 years with moderate or severe chronic knee ... from the University of Melbourne randomly assigned 282 patients ... no acupuncture or sham or pretend laser treatment. ... and acupuncturists blinded to laser and sham (inactive) laser ...
(Date:10/1/2014)... 1, 2014) Despite a policy focus on ... disabilities, this vulnerable population continues to have significant ... The Journal of the American Dental Association , ... Tufts University School of Dental Medicine report on ... at-home oral care provided by caregivers to adults ...
(Date:10/1/2014)... Insuranceragents.info has released a new blog post explaining how ... family members. , Life insurance plans provide important financial ... should always carry a life insurance policy as their ... the family. , Clients can choose from several ... coverage or from a permanent policy. No medical exam ...
(Date:10/1/2014)... Phoseon Technology, the pioneer in developing ... business worldwide. This rapid growth includes increased hiring for ... efforts. The company has experienced average annual growth rates ... this growth to continue in the future as new ... , “We are very pleased that UV ...
(Date:10/1/2014)... new genetic finding from Duke Medicine suggests that some ... might also be hard-wired to gain weight when exposed ... , An estimated 13 percent of people, all of ... knowing this could help them reduce heart disease with ... stress management. , "Genetic susceptibility, psychosocial stress and metabolic ...
Breaking Medicine News(10 mins):Health News:Study finds acupuncture does not improve chronic knee pain 2Health News:To improve oral health of adults with developmental disabilities, support caregivers 2Health News:To improve oral health of adults with developmental disabilities, support caregivers 3Health News:Life Insurance for Families - Clients Can Compare Affordable Rates Online! 2Health News:Phoseon Technology Continues to Drive Growth Worldwide 2Health News:Gene interacts with stress and leads to heart disease in some people 2
... The following is being,issued by Center for Consumer Freedom:, ... preparing,to celebrate time-honored traditions like caroling, tree-trimming, and,leaving cookies ... of trans fat,bans and frivolous lawsuits, serving baked goods ... the receiving end of a very un-merry obesity lawsuit., ...
... Strategic ... Plan, CLEVELAND, Dec. 20 ... Executive Officer,University Hospitals, has agreed to serve as the health system,s leader for,an ... Board of Directors, said, "I join my,Board colleagues in underscoring our support for ...
... Need, NORTH KINGSTOWN, R.I., Dec. 20 On ... of Dominion Diagnostics,joined together in the spirit of the ... RI. The party proved a sight to be seen; ... Ballroom, and,many guests dressed to the nines for the ...
... PICK ONE" ENCOURAGING ... TOGETHER, NEW YORK, Dec. 20 Just in time ... launch of "Kick One, Pick One",(KOPO), the network,s new pro-social ... more time together. Bowing Jan. 1, KOPO is an,on-air, online ...
... groundbreaking experiment published in Cloning & Stem Cells, scientists ... embryonic stem cell lines that open the door for ... an immune reaction in large segments of the population. ... have a simple genetic profile in the critical areas ...
... Vegas business and Oak Ridge National Laboratory are improving the ... heart failure. , The task for ORNL researchers Chuck Britton, ... Noninvasive Medical Technologies ZOE, a medical device that monitors a ... importance to members of the military and to thousands of ...
Cached Medicine News:Health News:Center for Consumer Freedom Releases 'Don't Sue Me Santa' Christmas Cookie Liability Waiver 2Health News:University Hospitals Chief Executive Officer Extends Contract 2Health News:University Hospitals Chief Executive Officer Extends Contract 3Health News:Dominion Diagnostics Supports Rhode Island's Toys for Tots Initiative at Its 2007 Holiday Celebration 2Health News:Nick at Nite Asks Families to Kick a Bad Habit, Pick a Good One in 2008 2Health News:Nick at Nite Asks Families to Kick a Bad Habit, Pick a Good One in 2008 3Health News:Human embryonic stem cell lines created that avoid immune rejection 2Health News:Nevada company, ORNL develop potential lifesaver 2
(Date:9/30/2014)... 30, 2014 Arbor Pharmaceuticals, LLC. - ... Global Markets Direct,s, ,Arbor Pharmaceuticals, LLC. - Product ... the Arbor Pharmaceuticals, LLC.,s pharmaceutical research and development ... the current therapeutic developmental pipeline of Arbor Pharmaceuticals, ... therapeutics assessment by drug target, mechanism of action ...
(Date:9/30/2014)... BURLINGTON, Mass. , Sept. 30, 2014  Decision ... (PV) devices in Brazil , ... and China (BRIC) will see ... techniques are increasingly favored over surgical procedures. Although revenues ... care resources, reimbursement challenges, prolonged device approval times and ...
(Date:9/30/2014)... , Sept. 30, 2014  According to their ... of cancer clinical trials is going through a ... and the work of the current clinical trial ... of ,next generation, clinical trials, which will ultimately ... The company has been recognized by ...
Breaking Medicine Technology:Arbor Pharmaceuticals, LLC. - Product Pipeline Review - 2014 2Arbor Pharmaceuticals, LLC. - Product Pipeline Review - 2014 3Brazilian, Russian, Indian and Chinese Markets for Peripheral Vascular Devices Will See Strong Expansion Through 2023 2Brazilian, Russian, Indian and Chinese Markets for Peripheral Vascular Devices Will See Strong Expansion Through 2023 3Small Denver Company Pharmatech driving a large revolution in how cancer clinical trials are managed 2
... , April 27, 2010 Shire plc (LSE: ... it has received a Paragraph IV Notice Letter from Anchen,Pharmaceuticals, ... Application ("ANDA") for a generic version of Shire,s 1 mg, ... tablets, INTUNIV(TM).,Shire had previously reported in March 2010 ...
... April 27 For a second consecutive year, following the ... Auto Thefts) is cautioning Michigan drivers, and now auto dealers ... theft-related crimes.   , , ... increased vehicle security features, and the continuing success of Michigan ...
Cached Medicine Technology:Shire Receives INTUNIV(TM) Paragraph IV Notice Letter From Anchen 2Shire Receives INTUNIV(TM) Paragraph IV Notice Letter From Anchen 3H.E.A.T. Warns Drivers, Auto Dealers of Continuing Trend in Unconventional Auto Crimes 2H.E.A.T. Warns Drivers, Auto Dealers of Continuing Trend in Unconventional Auto Crimes 3
Archimedes is an innovative specialty calculator. Forget having to remember complicated formulas, just enter the values and out come the results....
A handy, quick reference for physicians, nurses, and other health care providers treating cancer patients....
A handy quick-reference tool for busy residents and clinicians with key facts and points essential for day-to-day patient care....
Provides reliable information on the most commonly prescribed drugs, their side effects, interactions and cost of therapy....
Medicine Products: