Navigation Links
Data Supporting Boceprevir Response Guided Therapy Presented at American Association for the Study of Liver Diseases (AASLD) Annual Meeting
Date:11/1/2009

ribavirin therapy (defined as <1 log decrease in HCV viral load) after the 4-week lead-in period. Overall, 38 percent of null responders achieved SVR (19/50), with 25 percent (7/28) of patients who received 28 weeks of therapy and 55 percent (12/22) of patients who received 48 weeks of therapy achieving SVR. Patients with null response to peginterferon and ribavirin are considered to be among the most difficult to treat successfully and historically achieve a low rate of SVR.

"Although the numbers are small, this analysis of the HCV SPRINT-1 study data showed that it was possible to achieve SVR in a proportion of null responders to peginterferon and ribavirin when boceprevir was added to their backbone regimen," said Paul Kwo, M.D., associate professor of medicine and medical director, liver transplantation, Department of Medicine, Division of Gastroenterology/Hepatology, Indiana University School of Medicine, Indianapolis, and lead investigator of the study. "However, the risk of developing viral resistance to protease inhibitors in patients who do not achieve SVR must be carefully weighed against the potential benefits of treatment with this new class of direct antiviral agents. With the lead-in strategy, initial peginterferon and ribavirin responsiveness is determined prior to the addition of a protease inhibitor, thus allowing the physician to take into account the potential for the development of resistance."

The ongoing Phase III boceprevir registration studies employ the lead-in strategy for all patients and will provide greater insight into the relationship between peginterferon and ribavirin responsiveness and the likelihood of achieving SVR in a diverse patient population. These Phase III studies, in treatment-naïve patients (HCV SPRINT-2) and patients who failed prior treatment (HCV RESPOND-2), prospectively evaluate the use of rapid viral response (RVR) to determine which boceprevir patients can stop all treatment at
'/>"/>

SOURCE Schering-Plough Corporation
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8 9 10 11

Related medicine news :

1. Canary Foundation Commits to Supporting New Platform for Cancer Diagnostics
2. Food 4 Less Stores Giving Hope a Hand(R) in October by Supporting Breast Cancer Awareness Initiatives
3. Ralphs Stores Giving Hope a Hand(R) in October by Supporting Breast Cancer Awareness Initiatives
4. AstraZeneca Accepts Secretary of Defense Award for Supporting Employees Serving in National Guard and Reserve
5. Anthem Blue Cross and Blue Shield Foundation Grant Supporting American Diabetes Associations Family Link Program In Connecticut
6. livethesource(TM) Hosts Company Launch Event While Supporting The Brent Shapiro Foundations Annual Sober Night Out
7. CMSA Announces New Model ACT Supporting Case Management Programs
8. Hospice Foundation of America Presents New Educational Webinar on Supporting People with Intellectual Disabilities through Illness, Grief and Loss
9. The Sensory Research Center (SRC) Offers 2 for 1 Tickets for Benefit Concert Supporting Autism, Downs Syndrome, Cerebral Palsy and Other Disabilities.
10. Trust for Americas Health Praises Major Foundations for Supporting Prevention as a Central Part of Health Reform
11. American Humane Association Launches Innovative Therapy Animals Supporting Kids (TASK)(TM) Program
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/25/2014)... 25, 2014 The Little Gym of ... on Sunday, July 27 at Discovery Green in downtown ... Copperfield, Katy, Pearland, Friendswood, Spring, The Woodlands, Sugarland-Missouri City, ... , “We’re thrilled to be attending and performing ... Belcher who owns the Sugarland-Missouri City location. “We believe ...
(Date:7/25/2014)... (PRWEB) July 25, 2014 AttorneyOne.com, a recognized ... latest information from the FDA on Ibuprofen and Oxcarbazepine ... that one lot of Ibuprofen and one lot of Oxcarbazepine ... due to mislabeled packaging. Oxcarbazepine is used for the treatment ... , The reason for the recall is that Lot ...
(Date:7/25/2014)... Ticket Down is a reliable ... in Berkeley at California Memorial Stadium. With the post-World ... football, the organizers of the 2014 Guinness International Champions Cup ... North America. With teams representing La Liga, English Premier League, ... of the best football players from around the world to ...
(Date:7/25/2014)... On July 22, 2014, CEDR ... the nation’s number one provider of legally-compliant, individually ... partnership with TransAct Merchant Solutions’ National Association Program ... Chase Paymentech Solutions, LLC, which provides sales and ... are members of TransAct’s National Association Program (NAP) ...
(Date:7/25/2014)... 25, 2014 Hastings and Hastings, ... attorney’s fees with regard to personal injury claims, announces ... wide range of legal services for those that have ... another individual or corporation. Free initial consultation services gives ... of a potential personal injury claim . It ...
Breaking Medicine News(10 mins):Health News:The Little Gym of Houston to Attend Houston Family Magazine’s Family Fun Fest 2014 2Health News:Ibuprofen and Oxcarbazepine Tablets Recalled: AttorneyOne Monitors and Keep Consumers Informed 2Health News:Real Madrid vs. Inter Milan Tickets Berkeley: Ticket Down Slashes Ticket Prices on Guinness International Champions Cup Tickets at California Memorial Stadium 2Health News:Real Madrid vs. Inter Milan Tickets Berkeley: Ticket Down Slashes Ticket Prices on Guinness International Champions Cup Tickets at California Memorial Stadium 3Health News:Nuanced Media Client, CEDR HR Solutions, Partners with TransAct to Serve Medical, Dental, and Eye Care Professionals 2Health News:Hastings and Hastings Announces Complimentary Consultation Services 2Health News:Hastings and Hastings Announces Complimentary Consultation Services 3
... Business Coalition on Health releases nationwide eValue8,findings, ... to the eValue8,(TM) report of health plan ... Coalition on Health (NBCH), health plans could ... with their customers, enabling,improvements in patient safety, ...
... Nicotine Cessation Expert and ... Former ... just a,habit; it,s an addiction. Hazelden has been helping alcoholics and ... principles,of the Hazelden treatment experience help tobacco users find recovery, too. ...
... University Hospitals Case Medical Center finds that Deep ... Tourette Syndrome (TS). This first-of-its-kind study of five ... tic frequency and severity in some people who ... is a neurobehavioral disorder characterized by sudden, repetitive ...
... kill them, study finds , , MONDAY, Nov. 12 (HealthDay ... weapons that helps make community-associated methicillin-resistant Staphylococcus aureus ... be done, the study "provides a partial explanation of ... and gives a starting point in the development of ...
... dental mercury uses contribute to high mercury,levels in fish ... first time, that dental mercury air,emissions may be more ... WASHINGTON, Nov.12 The U.S. House,Subcommittee on Domestic ... a hearing on Wednesday, Nov. 14, to discuss FDA,s,responsibility ...
... Gov. Mitch,Daniels joined executives from Medco Health Solutions, ... company,s plans to build the world,s largest and ... growing,nationwide demand for lower-cost medicines. The new 318,000-square-foot,pharmacy, ... an area equivalent to,six and a half football ...
Cached Medicine News:Health News:National Survey Finds Employers are Challenging Health Plans to Better Use Resources to Prevent Illness and Improve Patient Safety 2Health News:National Survey Finds Employers are Challenging Health Plans to Better Use Resources to Prevent Illness and Improve Patient Safety 3Health News:National Survey Finds Employers are Challenging Health Plans to Better Use Resources to Prevent Illness and Improve Patient Safety 4Health News:Quit Smoking Tips For The Great American Smokeout Day - November 15 2Health News:University Hospitals Case Medical Center finds new treatment holds promise for Tourette syndrome 2Health News:University Hospitals Case Medical Center finds new treatment holds promise for Tourette syndrome 3Health News:Key to MRSA Virulence in Community Discovered 2Health News:Key to MRSA Virulence in Community Discovered 3Health News:Environmental Impacts of Dental Mercury Focus of U.S. House Oversight Hearing Wednesday 2Health News:Medco to Build World's Largest, Most Advanced Automated Pharmacy in Central Indiana 2Health News:Medco to Build World's Largest, Most Advanced Automated Pharmacy in Central Indiana 3Health News:Medco to Build World's Largest, Most Advanced Automated Pharmacy in Central Indiana 4Health News:Medco to Build World's Largest, Most Advanced Automated Pharmacy in Central Indiana 5
(Date:7/25/2014)... 2014 /PRNewswire-iReach/ -- "Australia Capsule Endoscopy Systems Market Outlook ... Capsule Endoscopy Systems market. The report provides value, in ... prices (in US dollars) within market segments: ... Capsule Endoscopes , Capsule Endoscopy Data Recorders ... also provides company shares and distribution shares data for ...
(Date:7/25/2014)... 25, 2014  Smile Train and its technology partner ... Virtual Surgery Simulator among leading global health innovations in ... in Washington, D.C. at The ... "Smile Train is honored to be represented ... of innovators in health and medicine that TEDMED unites ...
(Date:7/25/2014)... Calif. , July 25, 2014 /PRNewswire-iReach/ -- ... Nieto as the new Vice President of Business ... over 30 years in a number of different business ... the industry. These positions were primarily related to business ... over the past 30 years makes him a key ...
Breaking Medicine Technology:Australia Capsule Endoscopy Systems Market Analysis and Forecast to 2020 2Australia Capsule Endoscopy Systems Market Analysis and Forecast to 2020 3Australia Capsule Endoscopy Systems Market Analysis and Forecast to 2020 4Australia Capsule Endoscopy Systems Market Analysis and Forecast to 2020 5Smile Train and BioDigital Selected to Showcase Virtual Surgery Simulator in The Hive at TEDMED 2014 2Smile Train and BioDigital Selected to Showcase Virtual Surgery Simulator in The Hive at TEDMED 2014 3Contract Research Organization WCCT Global Welcomes Peter Nieto as Vice President of Business Development 2
... Feb. 2 InterMune, Inc.,(Nasdaq: ITMN ) ... Phase 3,CAPACITY program of pirfenidone in idiopathic pulmonary fibrosis ... InterMune will conduct a conference,call and webcast, with accompanying ... 8:00 a.m. EST (5:00 a.m. PST) on Tuesday,February 3. ...
... who experience erectile dysfunction between the ages of 40 and ... men without dysfunction, according to a new Mayo Clinic study. ... 80 percent higher risk of heart disease. "The highest risk ... Jennifer St. Sauver, Ph.D. The study was published in the ...
Cached Medicine Technology:InterMune to Announce Results of Phase 3 CAPACITY Program of Pirfenidone in IPF Tomorrow, February 3 2Mayo Clinic Study Finds Younger Men With Erectile Dysfunction at Double Risk of Heart Disease 2Mayo Clinic Study Finds Younger Men With Erectile Dysfunction at Double Risk of Heart Disease 3
... been selling replacement bulbs on ... we are extremely proud of ... out our catalog of replacement ... light bulbs specials. ,Check ...
... has been selling replacement bulbs ... and we are extremely proud ... Check out our catalog of ... discount light bulbs specials. ...
... been selling replacement bulbs on ... we are extremely proud of ... out our catalog of replacement ... light bulbs specials. ,Check ...
... has been selling replacement bulbs ... and we are extremely proud ... Check out our catalog of ... discount light bulbs specials. ...
Medicine Products: