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Data Show Common Allergy Tests Are Not Interchangeable
Date:5/8/2008

- Results Vary Widely Compared to Established Clinical Standards Using

ImmunoCAP -

PORTAGE, Mich., May 8 /PRNewswire/ -- Data published in the May issue of the Journal of Allergy and Clinical Immunology revealed variations in the results of three common allergy diagnostic blood tests used to quantify sensitivities to allergens. The study, conducted by allergy specialists at Mount Sinai School of Medicine, determined that the laboratory results from two other commercial tests for specific IgE were not equivalent to those measured by ImmunoCAP(R) Specific IgE blood test.

Previously published studies from thought-leading allergists have established threshold values for many food allergens. These values are often used to guide decisions about the severity of a patient's food allergy and subsequent management strategies. These published data are based upon values determined using ImmunoCAP technology, which have become well-established.

"Test results from the three different specific IgE assays are not interchangeable. This study underscores the importance of knowing which test is being used to generate the patient's results, particularly with food allergies, which can be life-threatening," said Robert Reinhardt, MD, professor of family medicine for Michigan State University College of Human Medicine and U.S. Medical Affairs Director, Phadia U.S. Inc.

Specific IgE is produced in the blood as a result of sensitization to an allergen and typically increases with exposure to that substance. High concentrations of food-specific IgE levels are predictive of a food-induced allergic reaction. These ImmunoCAP derived values provide a quantitative assessment of allergen-specific IgE antibody, helping clinicians determine the severity of an allergy and guide patient management strategies.

The assays used in this study included ImmunoCAP, Turbo-MP (Agilent Technologies offered by LabCorp (Laboratory Corporat
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SOURCE Phadia U.S. Inc
Copyright©2008 PR Newswire.
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