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Data Published in Anticancer Research Show ChemoFx(R) Assay Results Correlate With Outcomes in Breast Cancer
Date:7/1/2008

Ability to Perform Testing on Biopsy-sized Specimens Allows for Greater

Clinical Utility in all Breast Cancer Settings

PITTSBURGH, July 1 /PRNewswire/ -- Precision Therapeutics Inc. announced today that results from the ChemoFx(R) Assay, a cell-based test that examines the response of a specific patient's tumor to various chemotherapies, correlate with pathologic complete response in breast cancer patients treated with neoadjuvant (pre-operative) chemotherapy. Data published in Anticancer Research show that the assay accurately predicted response to therapy 75% of the time. This study, done in conjunction with US Oncology, a leading cancer research and treatment network, represents the company's first publication in the breast cancer setting.

"Achieving pathologic complete response is an important goal for patients in the neoadjuvant breast cancer setting. Precision Therapeutics' data demonstrate that ChemoFx has the potential to predict which chemotherapy regimens will be most effective, thus potentially sparing patients from unnecessary toxicity associated with ineffective treatment," said Joyce O'Shaughnessy, MD, of Baylor-Sammons Cancer Center in Dallas and associate study investigator. Ongoing definitive trials are evaluating whether the promising results from our study with ChemoFx will help us design more personalized pre-operative treatment strategies."

Other major findings of the study addressed technical aspects of the assay, including the feasibility of performing the test on small amounts of tissue and the reproducibility of test results. The study demonstrated that the test could be successfully performed 84% of the time on tissue samples as small as 35 mg (2 14 gauge core needle biopsies). This finding is significant because historically chemoresponse assays have been limited by the need for a large amount of tissue (1-5 grams). The small tissue requirement demonstrated in this study is crucial in the breast c
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SOURCE Precision Therapeutics Inc.
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