Navigation Links
Dartmouth study uses the patient's tumor to form vaccine
Date:11/24/2010

cine treatment, 63% of the patients who developed an immune response against their own tumor were alive and tumor-free. In contrast, just 18% of the patients who did not develop an immune response against their own tumor were alive and tumor-free.

"We showed that a tumor lysate-pulsed DC vaccine can induce immune responses against the patient's own tumor in a high proportion of patients," stated Dr. Barth, who has been investigating DC-based vaccines in mice and patients for more than 10 years. "There were two basic questions we wanted to answer: one, can we generate an antitumor response, and two, does it matter? From our research, the answer to both questions is yes."

He said DC vaccines have been a research interest at many institutions, and previous studies showed that DC vaccines could not reduce or eliminate measurable metastatic tumor deposits. "It turned out we were asking the T-cells to do too much," he commented. "The small number of T-cells that are generated by a vaccine can't destroy a large tumor. However, what they may be able to do is search out and destroy tumor cells that exist as only microscopic tumor deposits. Once we brought patients into a measurable tumor-free condition with surgery, the anti-tumor T-cells induced by the DC vaccine may help keep them that way."

Follow-up studies are necessary to more fully understand the mechanisms of the DC vaccine and its impact on long-term survival rates, Dr. Barth said. He believes this study may open the door to a significant change in cancer treatment in the future. The DC vaccine is non-toxic, while traditional chemotherapies are highly toxic. "It's your own immune system doing the fighting," he commented. "I'm optimistic that this really will have an impact."


'/>"/>

Contact: Steven P. Bjerklie
steven.p.bjerklie@dartmouth.edu
603-653-9056
Dartmouth-Hitchcock Medical Center
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Despite Treatment, Employees with Depression Generate Higher Absentee Costs, According to Thomson Reuters Study
2. American Council on Exercise (ACE) Study Reveals Kettlebells Provide Powerful Workout in Short Amount of Time
3. TV drama can be more persuasive than news program, study finds
4. Study carried out into biological risks of eating reptiles
5. Neuroimaging study may pave way for effective Alzheimers treatments
6. Study finds racial gaps continue in heart disease awareness
7. Luth Researchs IndicatorEDG(TM) Study Finds Americans Hopes of Achieving Their Dreams Are Fading
8. First blinded study of venous insufficiency prevalence in MS shows promising results
9. Soothing infants with food focus of childhood obesity study
10. People with anxiety disorder less able to regulate response to negative emotions, study shows
11. American Heart Association Rapid Access Journal Report: Study Finds Racial Gaps Continue in Heart Disease Awareness, Low Knowledge of Heart Attack Warning Signs Among Women
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/1/2014)... NY (PRWEB) September 02, 2014 ... at Apex Healthcare, LLC as a 2014 Professional Woman ... prestigious distinction for leadership in office management. As the ... country, spanning virtually every industry and profession, the National ... community with over 600,000 members and nearly 300 Local ...
(Date:9/1/2014)... City, NY (PRWEB) September 02, 2014 ... Brinkley, Office Manager at Gibson Orthopedics ... Woman of the Year. Ms. Brinkley is recognized ... administration. As the largest, most-recognized networking organization of ... and profession, the National Association of Professional Women ...
(Date:9/1/2014)... Texas (PRWEB) September 02, 2014 Spine ... magazine’s annual Reader’s Choice ‘Best of 2014’ award based ... markets: Northeast Tarrant County, Las Colinas & Coppell, Rockwall ... Texas would like to thank our patients and the ... Team Texas as LIVING magazine’s ‘Best of 2014’ in ...
(Date:9/1/2014)... Washington State University study of deadly force were more ... But when it came time to shoot, participants were ... pull the trigger against them than against armed white ... Journal of Experimental Criminology , grow out of ... of ethnic and racial minorities shot by police. The ...
(Date:9/1/2014)... UWDress.com, a well-known wedding dress manufacturer and retailer, has ... dresses for its new and old clients. These ... category. What’s more, they are offered at very affordable ... specially launched to celebrate the coming of autumn. ... great appreciation from worldwide clients. Now, the company is ...
Breaking Medicine News(10 mins):Health News:National Association of Professional Women Announces Victoria Smith, Office Manager at Apex Healthcare, LLC, a 2014 Professional Woman of the Year 2Health News:National Association of Professional Women Announces Laura Brinkley, Manager, Gibson Orthopedics Pain Treatment & Cardiology Clinic, a 2014 Professional Woman of the Year 2Health News:Spine Team Texas chosen in LIVING Magazine’s Reader’s Choice Awards 2Health News:WSU 'deadly force' lab finds racial disparities in shootings 2Health News:WSU 'deadly force' lab finds racial disparities in shootings 3Health News:2014 Lime Green Bridesmaid Dresses Offered At UWDress.com 2
... ... being of patients by advocating for physician patient relationships which ensure optimal patient care ... and presentation of guidelines such as breast cancer screening that can negatively impact patients. ... (PRWEB) January ...
... ... Deepak Chopra, M.D. and David Simon, M.D. introduces a 100% natural lip balm based on ... ... ingredients, Adara Organic Lip Balm will keep your lips moisturized and smooth this winter season. ...
... , - More relief goods, staff arrive, but challenges ... , - Agency reports "race against clock" to save lives ... , Jan. 16 World Vision relief ... a boost as relief goods began arriving in Haiti,s quake-ravaged capital city ...
... , Pan ... , WASHINGTON , Jan. 16 The ... relief efforts using a new Portuguese website called www.AjudaPanamericana.org ... States announced. , AjudaPanamericana.org is the third language option offered by ...
... WASHINGTON , Jan. 16 The ... is sending additional specialists to Haiti to help ... of individuals in makeshift medical facilities are in dire need ... ) , Global Health Bureau,s Clydette Powell ...
... National PSA to run in all playoff games this Weekend on Fox ... The National Football League (NFL) and the NFL Players Association (NFLPA) are ... of the earthquake in Haiti . The NFL and its network ... valued at $1.5 million to promote donations. In addition, NFL ...
Cached Medicine News:Health News:Southern Medical Association Takes Position on Breast Cancer Screening 2Health News:Southern Medical Association Takes Position on Breast Cancer Screening 3Health News:Southern Medical Association Takes Position on Breast Cancer Screening 4Health News:Pamper and Soothe Your Lips with the Chopra Center's New Adara Certified Organic Lip Balm 2Health News:HAITI QUAKE: World Vision Situation Update 2Health News:HAITI QUAKE: World Vision Situation Update 3Health News:HAITI QUAKE: World Vision Situation Update 4Health News:Haiti Relief Site Now in Portuguese 2Health News:Haiti Relief Site Now in Portuguese 3Health News:USAID's Global Health Bureau Responds to Haiti's Medical Crisis 2Health News:USAID's Global Health Bureau Responds to Haiti's Medical Crisis 3Health News:NFL Donates More Than $2 Million for Red Cross Disaster Response in Haiti 2Health News:NFL Donates More Than $2 Million for Red Cross Disaster Response in Haiti 3Health News:NFL Donates More Than $2 Million for Red Cross Disaster Response in Haiti 4
(Date:8/29/2014)... DUBLIN , Aug. 29, 2014 ... the "China Orthopedic Instrument Industry Report, 2014-2017" ... accelerated aging population and rising proportion of reimbursement for ... been effectively released, with its scale presenting a CAGR ... joint products are three product segments of orthopedic instruments ...
(Date:8/29/2014)... , August 29, 2014 ... Oil Market by Extraction type (SFE, Cold Pressed, ... Personal Care, Pharmaceutical, Food Supplements, Fragrance, & Others) - ... MarketsandMarkets, defines and segments the Amaranth Seed Oil ... market size in terms of value. The Amaranth ...
(Date:8/29/2014)... SPRING, Md. , Aug. 29, 2014  United ... that the U.S. District Court for the District of ... its favor in the company,s case against Sandoz, Inc. ... Judge Peter Sheridan ruled that U.S. Patent ... Inc., and enjoined Sandoz from marketing its generic product ...
Breaking Medicine Technology:China Orthopedic Instrument Industry Report, 2014-2017 2Amaranth Seed Oil Market worth $700.6 Million by 2019 2Amaranth Seed Oil Market worth $700.6 Million by 2019 3Amaranth Seed Oil Market worth $700.6 Million by 2019 4District Court Decision Received In Remodulin Patent Case 2
... EyeScience(TM) ( www.eyescience.com ) announced today that ... and Dry Eye Formula(TM) are the only ... from their offices and through mass market retail. This announcement ... growing demand for the most complete eye vitamins available for ...
... (Nasdaq: HOLX ) today announced that Jack Cumming, Chairman, ... London on Tuesday, December 1, 2009, at 11:15am (GMT). ... audio webcast of Hologic,s investor presentation on the investor section ... An archive of the presentation will be available for replay ...
Cached Medicine Technology:EyeScience(TM) Announces New Program to Improve Patient Compliance and Practice Profits 2EyeScience(TM) Announces New Program to Improve Patient Compliance and Practice Profits 3
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
Medicine Products: