Navigation Links
Dartmouth researcher finds novel genetic patterns that make us rethink biology and individuality
Date:11/7/2013

to exhibit the same mutations. Williams and colleagues analyzed the same 10 tissue samples in two unrelated people. They found several identical mutations, and detected these repeated mutations only in kidney, liver and skeletal body tissues. Their research examined "mitochondrial DNA" (mtDNA)a part of DNA that is only inherited from the mother.4 Technically all women would share mtDNA from one common female ancestor, but mutations have resulted in differences. The importance of Williams' finding is that these tissue-specific, recurrent, common mutations in mtDNA among unrelated study subjectsonly detected in three body tissuesare "not likely being developed and maintained through purely random processes," according to Williams. They indicate "a completely different model . a decidedly non-random process that results in particular mutations, but only in specific tissues."

If our human DNA changes, or mutates, in patterns, rather than randomly; if such mutations "match" among unrelated people; or if genetic changes happen only in part of the body of one individual, what does this mean for our understanding of what it means to be human? How may it impact our medical care, cancer screening, or treatment of disease? We don't yet know, but ongoing research may help reveal the answers.

Christopher Amos, PhD, Director of the Center for Genomic Medicine and Associate Director for Population Sciences at the Cancer Center, says, "This paper identifies mutations that develop in multiple tissues, and provides novel insights that are relevant to aging. Mutations are noticed in several tissues in common across individuals, and the aging process is the most likely contributor. The theory would be that selected mutations confer a selective advantage to mitochondria, and these accumulate as we age." Amos, who is also a Professor of Community and Family Medicine at Geisel, says, "To confirm whether aging is to blame, we would need to study tissues from
'/>"/>

Contact: Derik Hertel
derik.hertel@dartmouth.edu
603-650-1203
The Geisel School of Medicine at Dartmouth
Source:Eurekalert

Page: 1 2 3 4 5

Related medicine news :

1. Clemson, Dartmouth use $1.5M grant to develop mobile health technology
2. Dartmouth researchers receive $5.9 million grant from NIH for lung research
3. Dartmouth researchers develop molecular switch that changes liquid crystal colors
4. Dartmouth researchers test safety of Nivolumab in kidney cancer
5. Leap in leukemia treatment reported by Dartmouth researchers
6. Dartmouth medical research closes in on new tuberculosis vaccine
7. Mayo Clinic, Dartmouth-Hitchcock announce collaboration
8. Dartmouth researchers investigate the cognitive effects of athlete head impacts
9. UT Southwestern researchers discover a new driver of breast cancer
10. Sanders-Brown researchers produce new research on little-understood brain disease
11. UCSF researchers offer solutions to looming health-care provider shortage
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/25/2014)... New York, NY (PRWEB) October 26, 2014 ... aesthetic treatments, announces the most advanced and improved laser ... their effective and safe treatments like the lip ... treatments in keeping with specific focus areas of each ... services like cellulite reduction NYC . The company ...
(Date:10/25/2014)... Background: , In 1998 Bob Savage ... a pioneer in the field of establishing recovery community organizations. ... system and when he retired, he set out to answer ... service. , 1. Where are the people ... , 2. Can the recovery community be organized to ...
(Date:10/25/2014)... (PRWEB) October 25, 2014 Homeowners that ... has ‘gone bad’ need wonder no more. Clean Crawls ... homeowners should watch out for when it comes to ... according to the article released by Clean Crawls, can ... homeowners that any insulation that has deteriorated, become damp, ...
(Date:10/25/2014)... HealthDay Reporter FRIDAY, Oct. 24, ... sores -- herpes simplex -- might increase the risk of ... fact, being a carrier of certain antibodies to the virus ... "The identification of a treatable cause [herpes simplex] ... lead researcher Dr. Hugo Lovheim, an associate professor in the ...
(Date:10/25/2014)... HealthDay Reporter FRIDAY, Oct. 24, ... that spot increased risks for certain cancers, one might think ... But a new study suggests that, at least with ... out their genes doubled their risk of colon cancer were ... screened. "It didn,t make any difference, not at all," ...
Breaking Medicine News(10 mins):Health News:BioSkinLaser.Com Now Offers Advanced Medical Aesthetics Procedures 2Health News:BioSkinLaser.Com Now Offers Advanced Medical Aesthetics Procedures 3Health News:CCAR Accepting Nominations for the Bob Savage Recovery Advocate of the Year Award 2Health News:5 Signs Indicating That Insulation Needs Replacing as Told By Clean Crawls in Recent Article 2Health News:Studies Link Cold Sore Virus to Alzheimer's Risk 2Health News:Studies Link Cold Sore Virus to Alzheimer's Risk 3Health News:Knowing Genetic Risk for Cancer May Not Change Behavior 2
... of Thailand government. The country’s health minister Mongkol Na Songkhla ... rest of the nation. ,In a conference promoting ... rise at an alarming rate which leads to diabetes and ... said to suffer from diabetes. ,According to him ...
... that the same genetic regulator that triggers growth of ... role in the development of the lethal brain cancer ... they showed that knocking out the function of a ... ,The researchers said their findings suggest that targeting ...
... rights to commercial companies over clinical and preclinical trial ... medicines and harm public health, says Karin Timmermans of ... PLoS Medicine. ,Writing in a personal capacity, ... to produce generic versions of the "flu drug" oseltamivir ...
... a prominent hospital in Toronto for people with chronic diseases ... the Norwalk virus.// ,Diane Whidden, a spokesperson for ... affected. ,The hospital usually has hundreds of patients, ... are 20 active cases only in a capacity of 500-beds. ...
... mathematical model of disease cycles developed at the University ... ,Speaking in a symposium titled "New Vistas in ... meeting of the American Association for the Advancement of ... discuss how models that she and coworkers have developed ...
... dominated, the retro Sadhana cut and Dev Anand cowlick made ... gurus. ,Hair salons registered up to 75 percent ... spruced up on grooming rituals in preparation for Valentine's Day. ... went for a special hairdo - a crazy and more ...
Cached Medicine News:Health News:'Gateway' Gene Discovered for Brain Cancer 2Health News:Drug Companies Should Not Have a Monopoly Over Clinical Trial Data 2Health News:Mathematical Model Predicts Cholera Outbreaks 2Health News:Red Ribbons, Curls and Retro Hairstyles Popular on Valentine's Day 2
(Date:10/22/2014)... IRVINE, Calif. , Oct 22, 2014 ... Irvine, California , announced the receipt ... Small Business Innovation Research award (SBIR) from the National Institute of ... will fund the development of a Pan-HIV Protein Microarray ... the HIV-1 and HIV-2 subtypes and aid in the ...
(Date:10/22/2014)... , Oct. 22, 2014 Moms are ... health trackers for themselves and their kids, according to ... Report: Health & Fitness Go Mobile for Moms, the ... Series. BabyCenter, the number 1 pregnancy and parenting web ... that 55 percent of moms surveyed say they can,t ...
(Date:10/22/2014)... PORTLAND, Oregon , October 22, 2014 ... titled, "Global Disposable Gloves Market (Product type, Form, End ... Company Profiles, Demand, Insights, Analysis, Research, Report, Opportunities, Segmentation ... the global disposable gloves market. Based on key trends ... to be valued at $7.9 billion by 2020, registering ...
Breaking Medicine Technology:Biomarker Discovery Company, Antigen Discovery Inc., Awarded an NIH Phase I Small Business Innovation Research Grant to Develop a Pan-HIV Protein Microarray Chip 2BabyCenter Finds Mom Ready to Live the "Measured Life" in its U.S. Mobile Mom 2014 Report: Health & Fitness Go Mobile for Moms 2BabyCenter Finds Mom Ready to Live the "Measured Life" in its U.S. Mobile Mom 2014 Report: Health & Fitness Go Mobile for Moms 3BabyCenter Finds Mom Ready to Live the "Measured Life" in its U.S. Mobile Mom 2014 Report: Health & Fitness Go Mobile for Moms 4Global Disposable Gloves Market Expected to Grow to $7.9 Billion by 2020 - Allied Market Research 2Global Disposable Gloves Market Expected to Grow to $7.9 Billion by 2020 - Allied Market Research 3Global Disposable Gloves Market Expected to Grow to $7.9 Billion by 2020 - Allied Market Research 4
Latex agglutination slide test for the qualitative and semi-quantitative in vitro determination of Rheumatoid Factor in serum....
For the quantitative in vitro determination of Carbon Dioxide in serum and plasma....
For the quantitative in vitro determination of Uric Acid in serum, plasma and urine...
The BUN method used on the Dimension clinical chemistry system is an in vitro diagnostic test intended for the quantitative determination of urea nitrogen in serum, plasma and urine....
Medicine Products: