Navigation Links
Dana-Farber/Provenge: Approval of prostate cancer immunotherapy-new era of cancer treatments
Date:4/29/2010

BOSTONToday's announcement that the U.S. Food and Drug Administration has approved Provenge, a new form of therapy for some prostate cancer patients, marks the beginning of an era in which patients' own immune systems become part of the standard therapeutic arsenal against cancer, say Dana-Farber Cancer Institute investigators who led a study of the treatment's effectiveness in patients.

The study the results of which were presented most recently at the 2010 Genitourinary American Society of Clinical Oncology's annual meeting is the first large, controlled clinical trial to show that an immune system-based therapy can extend the lives of cancer patients, according to the trial's leader, Philip Kantoff, MD, of Dana-Farber.

"For more than 20 years, scientists have been working on harnessing the immune system in a way that has beneficial effects for cancer patients, notably the prolongation of survival," Kantoff said. "Our study provides proof that such an approach can work."

Unlike preventive vaccines, which bolster the immune system to protect people from contracting an illness, Provenge is an "autologous cellular immunotherapy," or a therapeutic vaccine, that marshals the immune system's disease-fighting forces for people who already have prostate cancer.

The immunotherapy is produced by removing some of a patient's white blood cells a process called leukapheresis and then exposing them to a protein from prostate cancer cells and a stimulatory molecule. The process primes the white blood cells to stimulate the immune system and attack prostate cancer when they are re-injected into the body.

The clinical study, a Phase III trial conducted at cancer treatment centers across the country, enrolled 512 patients with advanced prostate cancer that had spread beyond the prostate gland and that grew even when deprived of the hormone androgen, a condition known as metastatic hormone-resistant prostate cancer. Patients
'/>"/>

Contact: Teresa Herbert
teresa_herbert@dfci.harvard.edu
617-632-5653
Dana-Farber Cancer Institute
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. FDA Approval of new Prostate Treatment Shows Promise of Cancer Immunotherapy
2. Prostate Cancer Vaccine Gains FDA Approval
3. Third European Novel Food Approval Received by Tahitian Noni International
4. Prostate Cancer Vaccine May Get FDA Approval
5. Almac to Improve Label Approval Process in Clinical Trials
6. Mega Stock Picks (megastockpicks.com) Initiates Coverage on FDA Approval for POZEN, Inc.(NasdaqGM: POZN) Drug Vimovo with Immediate Buy Recommendation
7. Yondelis(R) Receives Five New Approvals Outside the European Economic Area
8. Hard to Treat Diseases (HTDS) Acquired Varicella Approval in Guatemala
9. Physician calls for more rigorous standards for drugs up for FDA approval
10. Approval of Kansas Smoke-Free Legislation Is Historic Win for Health
11. FDA Cancer Drug Approval Rate Highlighted in JNCI
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/1/2015)... 01, 2015 This year for Oral Cancer ... Cancer Foundation for an Open House to offer complimentary oral ... to 4 p.m. An appointment is required and can be ... at 212-689-0024. In addition, Herald Square Dental and The ... entire month of April at the reduced cost of $39 ...
(Date:4/1/2015)... 01, 2015 Bird B Gone, the ... residential applications now offers a complete line of ... of bird netting products quickly, safely and efficiently. , ... of any bird netting installation. It’s important to determine ... stages of a project. This includes deciding whether to ...
(Date:4/1/2015)... After a particularly harsh winter, many roads are now littered ... damage, so Amica Insurance has tips to help ... from AAA: , , Inspect tires: Tires ... manufacturer’s recommended levels. , Inspect suspension: ... wear can be signs of bad shocks or struts. Have ...
(Date:4/1/2015)... 2015 Taking an important step forward ... for Nursing Commission for Nursing Education Accreditation (NLN CNEA) ... first NLN CNEA Board of Commissioners. Working with executive ... 15-member board will provide leadership and direction to accreditation ... decisions for nursing programs that seek accreditation from the ...
(Date:4/1/2015)... 2015 BioPlus Specialty Pharmacy ... has released a new app to keep health care ... chronic hepatitis C virus (HCV) infection. This ‘HCV Treatment ... from the American Association for the Study of Liver ... new direct-acting oral medications to treat HCV have been ...
Breaking Medicine News(10 mins):Health News:Herald Square Dental Celebrates Oral Cancer Awareness Month 2Health News:Bird B Gone Now Carries Complete Bird Netting Hardware 2Health News:Bird B Gone Now Carries Complete Bird Netting Hardware 3Health News:Prepare for potholes with 7 tips from Amica Insurance 2Health News:NLN Commission for Nursing Education Accreditation (NLN CNEA) Announces Inaugural Commissioners 2Health News:NLN Commission for Nursing Education Accreditation (NLN CNEA) Announces Inaugural Commissioners 3Health News:BioPlus Specialty Pharmacy Releases ‘HCV Treatment Path’ App for Hepatitis C Providers 2
... May 22 Setaram Inc., a leading,manufacturer ... gas sorption and high pressure mass spectroscopy ... to announce the,appointment of Bruce Jamieson as ... recent acquisition of Hy-Energy LLC (Newark, CA), ...
... Minimally Invasive P3(TM) (Pioneer Peek-on-Peek) ... Technology Motion Preservation Device, DRIEBERGEN, ... announced the BacJac(TM),Interspinous Decompression System (IDS) will be market ... Switzerland., The BacJac system is designed to relieve ...
... HHS Secretary Mike,Leavitt today announced efforts underway at ... Centers for Medicare & Medicaid Services (CMS),that will ... the quality,of medical care., "This initiative will ... of medical products on the market," Secretary Leavitt ...
... 21, 2008 If you were sick, wouldnt you ... you" Or a treatment that prevents you from ever ... of clinical and translational science provides the bridging force ... Editor, Scott A. Waldman, MD, PhD, and Executive Editor, ...
... 22 Accenx Technologies, Inc.,announced today that ... Authorized,Subcontractor Program and is now part of ... services to the healthcare industry. From,this new ... to its already robust client roster, develop ...
... The topic of today,s,congressional subcommittee hearing on animal-disease ... Kansas and should serve several,purposes:, * Underscore ... combat the real and present threat of diseases ... economy., * Demonstrate the urgency of addressing ...
Cached Medicine News:Health News:Setaram Inc. Appoints New CEO/VP 2Health News:Pioneer(R) Surgical Technology Introduces the BacJac(TM) Interspinous Decompression System to the European Spine Market 2Health News:New Efforts to Help Improve Medical Products for Patient Safety and Quality of Medical Care 2Health News:New Efforts to Help Improve Medical Products for Patient Safety and Quality of Medical Care 3Health News:New Efforts to Help Improve Medical Products for Patient Safety and Quality of Medical Care 4Health News:Unlocking the promise of clinical and translational science 2Health News:Accenx Technologies Joins Sun's Authorized Subcontractor Program 2Health News:Tip Sheet: Kansas Responds to Congressional Hearing on Animal Disease Research 2
(Date:4/1/2015)... NEW YORK , April 1, 2015  The ... ("ASPX" or the "Company") by Teva Pharmaceutical Industries ("Teva") ... action, shareholder rights law firm.  The investigation focuses on ... law by the Board of Directors of ASPX for ... 30, 2015, the Company announced a definitive agreement for ...
(Date:4/1/2015)... April 1, 2015 Oramed Pharmaceuticals ... clinical-stage pharmaceutical company focused on the development of oral ... been enrolled in its Glucose Clamp Study. The study ... Science Center at San Antonio ... supervision of Professor Ralph DeFronzo . ...
(Date:4/1/2015)... KONG , April 1, 2015 Jintian ... code: 2211) announced that Mr. Jin Dongtao, chairman and ... the Company, representing 2% of the existing entire issued ... at HK$2.82 per share with the total amount of ... Mr. Jin Dongtao,s shareholding will increase from 45.17% to ...
Breaking Medicine Technology:WeissLaw LLP: Auspex Pharmaceuticals Inc. Acquisition By Teva Pharmaceutical Industries May Not Be In The Best Interest of ASPX Shareholders 2Oramed Enrolls First Patient in its Glucose Clamp Study for Oral Insulin 2Oramed Enrolls First Patient in its Glucose Clamp Study for Oral Insulin 3Chairman of Jintian Pharmaceutical Purchased Approximately HK$113 Million Worth of Shares Citing Confidence in Company's Development in Online and Offline MacroHealth Business 2Chairman of Jintian Pharmaceutical Purchased Approximately HK$113 Million Worth of Shares Citing Confidence in Company's Development in Online and Offline MacroHealth Business 3Chairman of Jintian Pharmaceutical Purchased Approximately HK$113 Million Worth of Shares Citing Confidence in Company's Development in Online and Offline MacroHealth Business 4Chairman of Jintian Pharmaceutical Purchased Approximately HK$113 Million Worth of Shares Citing Confidence in Company's Development in Online and Offline MacroHealth Business 5
... BNVI ) announced today that it will release ... ended September 30, 2010 on Thursday, November 11, 2010. The ... the financial results on Thursday, November 11, 2010 at 5:00 ... by dialing (877) 317-6789 or (412) 317-6789, or can listen ...
... Eli Lilly and Company (NYSE: LLY ) ... today presented an $11.6 million check to the United ... employees and retirees and a matching gift amount from ... Central Indiana chapter and other United Way chapters, 2010 ...
Cached Medicine Technology:Lilly Surpasses United Way 2010 Campaign Goal 2
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
Medicine Products: