Navigation Links
Daily aspirin usage associated with lower cancer mortality
Date:8/10/2012

Daily aspirin usage is associated with lower overall cancer mortality, but the association may be smaller than what was previously believed, according to a study published August 10 in the Journal of the National Cancer Institute.

A recent pooled analysis of randomized trials looking at the effects of daily aspirin use as a preventive measure for vascular events found a significant decrease in overall cancer mortality, of 37%, during a 5-year follow-up analysis, and 15% during a ten-year follow-up. Despite this finding, the effects of long-term daily aspirin use on cancer mortality remain largely unknown.

In order to determine the effects that long-term daily aspirin use has on overall cancer mortality, Eric J. Jacobs, Ph.D., of the Epidemiology Research Program at the American Cancer Society in Atlanta and colleagues looked at data on 100,139 men and women from the Cancer Prevention Study II Nutrition Cohort who had no prior history of cancer and had been taking a daily dose of aspirin. They used follow-up questionnaires to investigate peoples' aspirin intake.

The researchers found that among 5,138 participants who died because of cancer, daily aspirin usage was linked with slightly lower cancer mortality and was unrelated to the length of daily use. "Our results are consistent with an association between recent daily aspirin use and modestly lower cancer mortality," the authors write. However, the estimated reduced risk of 16% was much lower than the 37% reduction seen during the five-year follow-up period in the pooled analysis. Still, the researchers write, "Even a relatively modest benefit with respect to overall cancer mortality could still meaningfully influence the balances of risk and benefits of prophylactic aspirin use."

The authors do point out a potential limitation of their studynamely that it was an observational study, not a randomized trial, so they could have either underestimated or overestimated the size of reduction in cancer mortality from aspirin usage because of confounding factors.

In an accompanying editorial, John A. Baron, M.D., of the Department of Medicine at the University of North Carolina School of Medicine writes that the findings of the study reinforce the idea that there is a link between daily aspirin use and reduced cancer mortality. "The drug clearly reduces the incidence and mortality from luminal gastrointestinal cancers, and it may similarly affect other cancers," he writes, and noted that the findings from the American Cancer Society study may be "conservative." However, he cautions that, "As for any preventative intervention, the benefits must be balanced against the risks, particularly when the benefits are delayed whereas the risks are not."


'/>"/>
Contact: Zachary Rathner
Zachary.Rathner@oup.com
301-841-1286
Journal of the National Cancer Institute
Source:Eurekalert

Related medicine news :

1. Study adds to evidence daily aspirin linked to lower cancer mortality
2. Intuitive Number Sense Makes Daily Life Easier
3. Some Diabetics May Not Benefit From Daily Aspirin
4. Daily Coffee May Help Keep Grim Reaper Away
5. How the brains daily clock controls mood: A new project
6. U.S. Children Exposed to Hours of Background TV Daily
7. Women Less Apt Than Men to Get Recommended Daily Exercise
8. Aspirin protects against Barretts esophagus
9. Aspirin as Effective as Warfarin for Heart Failure: Study
10. Report says new evidence could tip the balance in aspirin cancer prevention care
11. Fertility drug usage and cancer risk
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/22/2017)... ... , ... Nurses at Apple Rehab Watch Hill , a nursing and ... certification in Closed Pulse Irrigation™ (CPI) for wound care. This qualifies ... for Medicare and Medicaid Services, to have a CPI machine that will provide better ...
(Date:8/22/2017)... ... , ... “Covert Awakening”: Walid’s spiritual journey from Islamic terrorist ... a consultant for the Intelligence Community. For more than ten years, she ... region. Julianne has written hundreds of reports for the US government analyzing ...
(Date:8/22/2017)... ... 2017 , ... Although Labor Day is not as popular for fireworks as ... displays, and numerous households celebrate the unofficial end of summer with backyard fireworks shows. ... , Kris Zambo, owner of Dynamite Fireworks in Hammond, Indiana, provides ...
(Date:8/21/2017)... ... , ... FCPX LUT Monochromatic Volume 2 is an all-new Look-Up Table color-grading ... grades to footage. A LUT is a Lookup Table that contains a mathematical formula ... indicated by the table. This pack comes with 60 different monochromatic CUBE LUT files. ...
(Date:8/21/2017)... CA (PRWEB) , ... August 21, 2017 , ... The ... how exactly are we supposed to get things done in a healthy way these ... And, they’re launching a crowdfunding campaign on August 28 to introduce Deskcise Pro™– the ...
Breaking Medicine News(10 mins):
(Date:8/15/2017)... -- Diplomat Pharmacy, Inc. (NYSE: DPLO), is now dispensing ... residents. Naloxone is available without a prescription ... G-3320 Beecher Road. ... is intended to block or reverse the effects of ... consciousness. The medication is often carried by first responders ...
(Date:8/11/2017)... CAESAREA, Israel , Aug. 11, 2017 ... company with mobile health and big data solutions, today ... results on Monday, August 14 and host a conference ... second quarter 2017 operating and financial results and its ... call will be hosted by Erez Raphael , ...
(Date:8/7/2017)... Zimmer Biomet Holdings, Inc. (NYSE and SIX: ZBH), ... Board of Directors has approved the payment of a quarterly ... The cash dividend of ... 27, 2017 to stockholders of record as of the close ... are subject to approval of the Board of Directors and ...
Breaking Medicine Technology: