Navigation Links
Daily Gene Rhythms May Be Off in Depressed People
Date:5/13/2013

terns were too varied.

"This is very clear evidence that the 'clock' in the brain is disrupted in depression," Akil said.

That makes sense, since doctors and researchers have long seen signs of a disturbed circadian rhythm in people with depression, said Eva Redei, a professor of psychiatry at the Northwestern University Feinberg School of Medicine in Chicago.

Those signs, Redei said, include sleep problems -- like sleeping too much or too little -- and abnormal activity in the "stress hormone" cortisol, which follows a daily rhythm. There also is a form of depression known as seasonal affective disorder (SAD) in which people suffer symptoms during the short days of winter but feel better during the sunnier seasons.

Experts do not know the precise cause of SAD, but Redei said it involves problems with the circadian rhythms.

This study, Redei said, "very nicely proves" that a disruption in the brain's daily gene activity exists in depression.

Both she and Akil said a big unknown is whether out-of-sync brain genes are an initial cause of depression or a result of the disorder.

Either way, Akil said she thinks the out-of-sync genes would feed people's symptoms. Think about how bad you feel, she said, when the body's normal rhythms are thrown off due to jet lag.

In the future, Akil said, the findings might help lead to new "biomarkers" for diagnosing depression or tracking how well the disorder is responding to treatment. But first, Redei said, researchers would have to see if the altered gene activity in the brain correlates with something doctors can actually measure -- such as something they can see in brain imaging or something they can analyze in the blood.

The findings might also help identify new "molecular targets" for depression treatment, Akil said.

Right now, antidepressant drugs target certain chemicals in the brain believed to contribute to depression -- most famously, the mood-regulating chemical
'/>"/>

Copyright©2012 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3

Related medicine news :

1. Karen Brimeyer’s Natural Leaky Gut Cure Review and Diet Plan Revealed by Daily Gossip
2. Aquaponics 4 You Review And Step By Step Aquaponics Secrets Exposed By Daily Gossip
3. New Jason Ferruggia Renegade Diet Review and Results Exposed by Daily Gossip
4. Heartburn No More Holistic Treatment System Review And Secrets Exposed Via Daily Gossip
5. How we decode noisy language in daily life
6. Depression in Alzheimers patients associated with declining ability to handle daily activities
7. DailyWorth.com and CutandBlow.com Team-Up to Make Annual Tax Deadline a Day to Get Excited About
8. Daily Aspirin Linked to Lower Risk for Deadly Skin Cancer in Women
9. Daily-use HIV prevention approaches prove ineffective among women in NIH study
10. Study of tenofovir vaginal gel shows daily dosing ineffective due to lack of adherence
11. Premium Astrology Client Care Team Leads Norah Guide to New Reviews Daily
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Daily Gene Rhythms May Be Off in Depressed People
(Date:8/28/2014)... FL (PRWEB) August 28, 2014 ... Recovery Month throughout September. This month will be ... treatment and mental health services. Along with other ... Group is helping to spread the word about ... in 1989, honoring the work of treatment and ...
(Date:8/28/2014)... THURSDAY, Aug. 28, 2014 (HealthDay News) -- Arguments between ... new study indicates. Parents in more than 200 ... 15 days. At the end of each day, mothers ... their relationship with their children. On days when ... dealings with their children were also strained, according to ...
(Date:8/28/2014)... (PRWEB) August 28, 2014 Biotronic, a ... leading intraoperative neurophysiology monitoring ("IONM") company, today announced the ... position of Chief Executive Officer effective immediately. Mr. Gecsey ... President and CFO in 2013 and has been an ... , “Bill’s efforts and achievements since joining the company ...
(Date:8/28/2014)... 28, 2014 Bank lending to the private ... down by 0.13% in real terms, and continuing to fall ... study by UHY, the international accountancy network. , UHY warns ... in particular, the credit crunch lingers on. , UHY says ... last year have been wiped out by inflation. Over the ...
(Date:8/28/2014)... is "stuck fermentation," when yeast that should be busily ... shuts down, leaving the remaining sugar to instead be ... A team of researchers including UC Davis yeast geneticist ... this problem. Working through a prion -- an ... system enables bacteria in fermenting wine to switch yeast ...
Breaking Medicine News(10 mins):Health News:Millennium Treatment Group Celebrates National Recovery Month 2Health News:Parents' Fights May Strain Bonds With Their Kids 2Health News:Biotronic NeuroNetwork Announces the Promotion of Bill Gecsey to CEO 2Health News:UHY Study Shows Bank Lending In USA Falling Behind G7 Peers 2Health News:UHY Study Shows Bank Lending In USA Falling Behind G7 Peers 3Health News:UHY Study Shows Bank Lending In USA Falling Behind G7 Peers 4Health News:UHY Study Shows Bank Lending In USA Falling Behind G7 Peers 5Health News:UHY Study Shows Bank Lending In USA Falling Behind G7 Peers 6Health News:UHY Study Shows Bank Lending In USA Falling Behind G7 Peers 7Health News:Prions can trigger 'stuck' wine fermentations, researchers find 2
... ... current overview and future projections of the US hospital information technology market , ... Chicago, IL (Vocus) June 2, 2009 -- ... electronic medical record, HIMSS Analytics cuts through the information clutter to clarify which ...
... 2 Darwin National,Assurance Company, a member company of ... AWH ), today announced that Kim Lloyd, Vice President,Healthcare ... at the American Hospital Association (AHA) Solutions Roundtable in,Chicago ... "Market, Claims,and Healthcare Risk Management Update - Measuring Your ...
... solution - Premerus(SM) Diagnostic Accuracy - at AHIP; demonstrates key ... , , FRANKLIN, Tenn., June 2 ... of medical cost management services, will highlight its groundbreaking solution ... America,s Health Insurance Plans (AHIP) Institute 2009. An industry first, ...
... 28, 2009Scientists at Columbia University,s Mailman School of ... Communicable Diseases of National Health Laboratory Service (NICD-NHLS), ... and Roche,s 454 Life Sciences Corporation have discovered ... hemorrhagic fever outbreak in Zambia and South Africa ...
... HARRISBURG, Pa., June 2 Governor Edward G. ... for the Lottery-funded PACENET prescription drug benefit for older Pennsylvanians, ... or no drug coverage now. , , "As ... economic times, providing comprehensive prescription medication coverage is more important ...
... top priority for PA Professional Fire Fighters Association through ... , HARRISBURG, Pa., June 2 The Pennsylvania ... will become the first Fire Fighter State Association to ... This program is part of its long standing commitment ...
Cached Medicine News:Health News:Understand ARRA Spending Allocations with HIMSS Analytics™ Market Intelligence 2Health News:Understand ARRA Spending Allocations with HIMSS Analytics™ Market Intelligence 3Health News:Darwin's Kim Lloyd to Speak on Panel at American Hospital Association Solutions Roundtable, June 3, 2009 2Health News:Darwin's Kim Lloyd to Speak on Panel at American Hospital Association Solutions Roundtable, June 3, 2009 3Health News:MedSolutions: Accurate Diagnosis Is Critical to Reducing Healthcare Costs 2Health News:MedSolutions: Accurate Diagnosis Is Critical to Reducing Healthcare Costs 3Health News:MedSolutions: Accurate Diagnosis Is Critical to Reducing Healthcare Costs 4Health News:New arenavirus discovered as cause of hemorrhagic fever outbreak in South Africa and Zambia 2Health News:New arenavirus discovered as cause of hemorrhagic fever outbreak in South Africa and Zambia 3Health News:Governor Rendell Proposes Offering Prescription Help to 30,000 More Older Adults as Part of Plan to Save $60 Million 2Health News:PA Professional Fire Fighters Association is First State Association in Nation to Offer Smoking Cessation Program 2Health News:PA Professional Fire Fighters Association is First State Association in Nation to Offer Smoking Cessation Program 3Health News:PA Professional Fire Fighters Association is First State Association in Nation to Offer Smoking Cessation Program 4
(Date:8/28/2014)... Takeda Pharmaceutical Company Limited ("Takeda") today announced ... of data from a 10-year epidemiology study to ... (U.S.) Food and Drug Administration (FDA), ... Ministry of Health, Labour, and Welfare (MHLW) / ... for pioglitazone containing medicines, including ACTOS (pioglitazone HCl). ...
(Date:8/28/2014)... -- Decision Resources Group finds that the market for colorectal cancer ... 2023 in the United States , ... Italy , Spain , the ... . The biosimilar erosion of Roche/Genentech/Chugai,s Avastin and Bristol-Myers ... launch of Eli Lilly,s Cyramza, Taiho Pharmaceutical,s Lonsurf, Alchemia,s HA-irinotecan ...
(Date:8/28/2014)... , Aug. 28, 2014  A candidate Ebola vaccine could be ... and Mali as early as ... vaccines aimed at preventing the disease that has killed more than ... . Human trials of this candidate vaccine, being ... are to be accelerated with funding from an international consortium in ...
Breaking Medicine Technology:Takeda Announces Completion of the Post-Marketing Commitment to Submit Data to the FDA, the EMA and the PMDA for Pioglitazone Containing Medicines Including ACTOS 2Takeda Announces Completion of the Post-Marketing Commitment to Submit Data to the FDA, the EMA and the PMDA for Pioglitazone Containing Medicines Including ACTOS 3Takeda Announces Completion of the Post-Marketing Commitment to Submit Data to the FDA, the EMA and the PMDA for Pioglitazone Containing Medicines Including ACTOS 4Takeda Announces Completion of the Post-Marketing Commitment to Submit Data to the FDA, the EMA and the PMDA for Pioglitazone Containing Medicines Including ACTOS 5Takeda Announces Completion of the Post-Marketing Commitment to Submit Data to the FDA, the EMA and the PMDA for Pioglitazone Containing Medicines Including ACTOS 6The Colorectal Cancer Market Will Remain Steady at $7.7 Billion by 2023, With Biosimilar Erosion Of Key Agents Being Balanced Out By the Launch Of Premium-Priced Therapies 2Ebola vaccine trials fast-tracked by international consortium 2Ebola vaccine trials fast-tracked by international consortium 3Ebola vaccine trials fast-tracked by international consortium 4Ebola vaccine trials fast-tracked by international consortium 5Ebola vaccine trials fast-tracked by international consortium 6Ebola vaccine trials fast-tracked by international consortium 7
... 2010 Spectrum Control, Inc. (Nasdaq: SPEC ), ... systems, announced today that it will release its fourth quarter ... after the close of the market. Following the release, Spectrum ... Time, to discuss the Company,s operating results for the quarter ...
... 29, 2010 Pfizer Animal Health today announced ... SYNB ), a privately held, Kansas ... of immunodiagnostic tests for companion and food production ... Veterinary immunodiagnostics, a methodology using antigen-antibody reaction to ...
Cached Medicine Technology:Pfizer Animal Health to Acquire Synbiotics Corporation, Entering Diagnostics Sector 2Pfizer Animal Health to Acquire Synbiotics Corporation, Entering Diagnostics Sector 3Pfizer Animal Health to Acquire Synbiotics Corporation, Entering Diagnostics Sector 4
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products: