Navigation Links
Daily Dialysis Has Risks, Benefits for Kidney Disease Patients

THURSDAY, Feb. 7 (HealthDay News) -- While daily dialysis can boost the overall health of kidney disease patients, it also can put them at higher risk for certain complications, a new study finds.

About 2 million people worldwide receive dialysis treatments. In dialysis, patients use a machine to artificially do what healthy kidneys should: eliminate waste and unwanted water from the blood. Standard dialysis involves three treatments a week, while frequent dialysis involves treatment once each day.

Of course, frequent dialysis requires accessing the blood more often, which typically is done using a long-lasting puncture site through which blood can be removed and returned.

Having the blood cleansed more frequently does typically improve patients' health and quality of life. It wasn't known, however, whether these patients also had any higher risk for complications related to repeated use of the blood-access site.

In this study, researchers led by Dr. Rita Suri, of Western University and Lawson Health Research Institute in London, Canada, conducted two 12-month clinical trials involving 245 patients. The patients were randomly selected to receive either in-center daily dialysis (six days a week) or standard dialysis (three days per week). Another 87 patients received either frequent home-based dialysis or standard dialysis.

In the first hospital-based trial, 31 percent of the 245 patients had to undergo repair of the blood-access site, lost use of the site or were hospitalized due to problems with the site. Complication rates were higher among the frequent-dialysis group: There were 33 repairs and 15 losses in the frequent-dialysis group compared with 17 repairs, 11 losses and one hospitalization in the standard-dialysis group.

Overall, the risk for a problem with the blood-access site was 76 percent higher in the frequent-dialysis group than in the standard-dialysis group, the researchers reported.

Similar trends were seen in the home-based trial, but the results were not statistically significant, according to the study results, which were published online Feb. 7 in the Journal of the American Society of Nephrology.

The findings are the first to show that frequent dialysis may have potentially harmful effects on the blood-access site, and provide valuable information for dialysis patients and their doctors, Suri said in a journal news release.

Two kidney experts said the results are not surprising, since dialysis is always a balancing act between risks and benefits.

"Frequent dialysis has been an area of intense interest since the publication in 2010 of a study from the Frequent Hemodialysis Network (FHN) that found a reduced rate of death and other events with frequent dialysis," said Dr. Steven Fishbane, director of clinical research in the department of medicine at North Shore-LIJ Health System in Great Neck, N.Y.

But he said the new study is a reminder that there is a downside in terms of complications. "Further work will be necessary to determine how to reduce these complications given the important improvement in patient health with frequent dialysis," he said.

Dr. Brian Radbill is associate professor of medicine in the department of nephrology at the Icahn School of Medicine at Mount Sinai, in New York City. He was also involved in the FHN trial that helped confirm the benefits of daily dialysis. Radbill said it was "not surprising" that daily treatments also increased patients' risk for complications.

The needles used to gain access to the bloodstream are relatively large and frequent use raises the odds of complications such as clots and aneurysms, Radbill said. In turn, those complications may lead to burdensome surgeries or loss of the blood-access site altogether.

Still, despite these risks, large clinical trials have "suggested an improvement in self-reported health-related quality of life in those patients who underwent more frequent [dialysis] as compared to those on conventional dialysis," Radbill said. That means that any risks, "must be weighed against the potential benefit of a better quality of life."

More information

The National Kidney Foundation has more about dialysis.

-- Robert Preidt

SOURCES: Brian Radbill, M.D., associate professor of medicine, department of nephrology, Icahn School of Medicine at Mount Sinai, New York City; Steven Fishbane M.D., director, clinical research, department of medicine, North Shore-LIJ Health System, Great Neck, N.Y., Journal of the American Society of Nephrology, news release, Jan. 7, 2013

Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Women Less Apt Than Men to Get Recommended Daily Exercise
2. U.S. Children Exposed to Hours of Background TV Daily
3. How the brains daily clock controls mood: A new project
4. Daily Coffee May Help Keep Grim Reaper Away
5. Some Diabetics May Not Benefit From Daily Aspirin
6. Intuitive Number Sense Makes Daily Life Easier
7. Study adds to evidence daily aspirin linked to lower cancer mortality
8. Daily aspirin usage associated with lower cancer mortality
9. Daily Aspirin May Cut Cancer Deaths, Another Study Finds
10. Working moms spend less time daily on kids diet, exercise, study finds
11. Daily Aspirin May Help Fight Prostate Cancer, But Not Breast Cancer
Post Your Comments:
Related Image:
Daily Dialysis Has Risks, Benefits for Kidney Disease Patients
(Date:11/24/2015)... ... November 24, 2015 , ... The ... waive paid entry and parking fees at several of their most popular properties, ... Great Barrington in support of REI’s Black Friday #OptOutside Campaign. The Trustees encourage ...
(Date:11/24/2015)... ... November 24, 2015 , ... In response to recent news ... deaths from prescription opioids in the United States grew 400 percent between 1999 and ... opioids were involved in 37 percent of all fatal drug overdoses. (1) , While ...
(Date:11/24/2015)... ... November 24, 2015 , ... Cancer patients, survivors, caregivers, ... at a live taping of the next CURE Connections® video series ... Cancers 2015 Symposium at Georgetown University Hotel & Conference Center in Washington, D.C. ...
(Date:11/24/2015)... AL (PRWEB) , ... November 24, 2015 , ... American ... announced today the opening of a holiday pop-up clinic located in Metro Atlanta’s North ... needs in a new and different way. The location is scheduled to operate through ...
(Date:11/24/2015)... ... November 24, 2015 , ... With Thanksgiving right around the ... safety tips to help protect your family and vehicle. , According to the National ... Thanksgiving holiday weekend. Amica is sharing the following safety tips from the NHTSA: ...
Breaking Medicine News(10 mins):
(Date:11/24/2015)... 24, 2015  Figure 1, a free mobile-first network ... cases, has launched a new completely redesigned web version ... allows radiologists, who work primarily on a desktop, to ... with its radiologist user base, Figure 1 is hosting ... North America (RSNA) Annual Meeting. ...
(Date:11/24/2015)... , Nov. 24, 2015  Family Rentals, a ... announced the launch of their newly designed, mobile-responsive ... --> Logo ... --> --> Now, renting essential ... and vacation, just got a whole lot easier ...
(Date:11/24/2015)... The uptake of recently approved and pipeline premium products for Type 1 ... 2021, says GBI Research . --> ... Diabetes Mellitus (T1DM), will be a key driver of market growth to ... The uptake of recently approved and pipeline premium products for Type ... to 2021, says GBI Research . ...
Breaking Medicine Technology: