Navigation Links
Daily Aspirin May Cut Cancer Deaths, Another Study Finds
Date:8/11/2012

By Steven Reinberg
HealthDay Reporter

FRIDAY, Aug. 10 (HealthDay News) -- People who take a low-dose aspirin daily may not only be helping their hearts, but also reducing their odds of dying from cancer, according to American Cancer Society researchers.

The lower risk of dying from cancer associated with aspirin, however, may not be as great as previously thought, say the authors of the large new study.

And aspirin's possible side effects -- notably the higher risk of bleeding episodes -- need to be taken into account when considering its use, they added.

"Expert committees that develop clinical guidelines will consider the totality of evidence about aspirin's risks and benefits when guidelines for aspirin use are next updated," said lead researcher Eric Jacobs, the society's strategic director of pharmacoepidemiology.

Jacobs said, until there are new guidelines, he doesn't recommend taking aspirin for cancer prevention.

"Although recent evidence about aspirin use and cancer is encouraging, it is still premature to recommend people start taking aspirin specifically to prevent cancer," he said.

Even low-dose aspirin can substantially increase the risk of serious gastrointestinal bleeding, Jacobs pointed out.

"Decisions about aspirin use should be made by balancing the risks against the benefits in the context of each individual's medical history. Any decision about daily aspirin use should be made only in consultation with a health care professional," he added.

The study was published in the Aug. 10 online issue of the Journal of the National Cancer Institute.

To look at the potential effect of daily aspirin use on cancer deaths, Jacobs' team used data from the Cancer Prevention Study II Nutrition Cohort, part of a larger long-term study on the effects of lifestyle factors on mortality.

This study included more than 100,000 men and women without a history of cancer, some of whom were taking aspirin daily.

Of the study participants, 5,138 eventually died from cancer.

Aspirin use was associated with an up to 16 percent lower risk of dying from cancer, which, however, was less than seen in another recent study, the researchers noted. In that analysis of randomized trials (where people were randomly assigned to either take aspirin or not take aspirin), aspirin use reduced cancer deaths by 37 percent during five years of follow-up and 15 percent during 10 years of follow-up, the authors noted in the report.

Nevertheless, "even a relatively modest benefit with respect to overall cancer mortality could still meaningfully influence the balances of risk and benefits of prophylactic [preventative] aspirin use," Jacobs' team concluded.

A limitation of the study is that it was an observational study, not a randomized trial. This could mean that the reduction in cancer deaths tied to aspirin use may be over- or under-estimated, the researchers noted.

Dr. John Baron, a professor of medicine at the University of North Carolina at Chapel Hill School of Medicine, who authored an accompanying journal editorial, said, "It's a remarkable idea that something that's in medicine cabinets around the world, and has been around for more than a century, can prevent cancer."

However, Baron is not recommending that people start taking aspirin to cut their odds for malignancy.

Why it works against cancer isn't known, Baron said, and he noted that the effect of aspirin is seen over time. For example, aspirin might start preventing colon cancer after a person had taken it for about 10 years.

During that time, however, that person might have gastrointestinal or brain bleeding caused by aspirin. So those risks and benefits need to be balanced, he noted.

The question is no longer whether aspirin prevents cancer, according to Baron, but rather whether the risks associated with aspirin are overshadowed by its benefits, he suggested. "But even the most pessimistic study shows a meaningful reduction," he added.

But while the new study found an association between aspirin use and reduced cancer risk, because it is not a randomized, controlled trial -- the "gold standard" for research -- it did not prove a cause-and-effect relationship.

More information

To learn more about aspirin and cancer, visit the U.S. National Cancer Institute.

SOURCES: Eric J. Jacobs, Ph.D., strategic director, pharmacoepidemiology, American Cancer Society; John A. Baron, M.D., professor of medicine, University of North Carolina at Chapel Hill School of Medicine; Aug. 10, 2012, Journal of the National Cancer Institute


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Daily aspirin usage associated with lower cancer mortality
2. Study adds to evidence daily aspirin linked to lower cancer mortality
3. Intuitive Number Sense Makes Daily Life Easier
4. Some Diabetics May Not Benefit From Daily Aspirin
5. Daily Coffee May Help Keep Grim Reaper Away
6. How the brains daily clock controls mood: A new project
7. U.S. Children Exposed to Hours of Background TV Daily
8. Women Less Apt Than Men to Get Recommended Daily Exercise
9. Aspirin protects against Barretts esophagus
10. Aspirin as Effective as Warfarin for Heart Failure: Study
11. Report says new evidence could tip the balance in aspirin cancer prevention care
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Daily Aspirin May Cut Cancer Deaths, Another Study Finds
(Date:9/19/2017)... ... September 19, 2017 , ... ... a neurosurgeon, has received a big bump in sales after recently going ... currently available on the Wal-Mart Stores-owned Jet.com, StackedNutrtion.com, RonnieColemanNutrition.com, RevNutrition.com and Go4ItNutrition.com. ...
(Date:9/19/2017)... Glen Cove, New York (PRWEB) , ... September 19, 2017 , ... ... that its dentist, Dr. Andrew Sami, was recently named one of the best dentists ... the leading lifestyle magazine for dental professionals nationwide. Every fall, the magazine features the ...
(Date:9/19/2017)... (PRWEB) , ... September 19, 2017 , ... ... update their mobile app offering. The new app provides a modern design with ... the overall shopping experience. , The fred’s Pharmacy mobile app includes hundreds of ...
(Date:9/18/2017)... ... September 19, 2017 , ... Food ... market , expected to grow at the fastest CAGR of 9.1% over the ... Food Protein Trends & Growth Opportunities in Asia’ – highlighting alternative proteins, sustainable ...
(Date:9/18/2017)... ... September 18, 2017 , ... Allegheny Health Network’s (AHN) string of standout ... fifth consecutive year, AHN earned more honors than any health care provider in the ... dinner Sept. 14 at the Omni William Penn Hotel in downtown Pittsburgh included:, ...
Breaking Medicine News(10 mins):
(Date:9/5/2017)... Oramed Pharmaceuticals Inc. (NASDAQ: ORMP ) (TASE: ... on the development of oral drug delivery systems, announced ... the U.S. Food and Drug Administration (FDA) regarding ORMD-0801, ... At the meeting, the FDA gave ... ORMD-0801, would be a Biologics License Application (BLA).  Such ...
(Date:9/1/2017)... , Sept. 1, 2017  Bayer will present the latest ... Society for Medical Oncology (ESMO) 2017 Congress, September 8-12 in ... include new preclinical and clinical data on Bayer,s marketed portfolio ... pipeline projects. "We ... minds in cancer research at ESMO," said Carsten Brunn ...
(Date:8/29/2017)... , Aug. 29, 2017 In a ... security, and regulatory compliance for veterinary practices of all ... a new partnership that makes TITAN,s expertise in physical ... available to Cubex,s clients nationally. ... buying and handling controlled substances is at risk today," ...
Breaking Medicine Technology: