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Daiichi Sankyo Quietly Grows While Other Pharmaceutical Firms Downsize
Date:10/1/2007

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The primary focus of Daiichi Sankyo's research and development is cardiovascular disease, including therapies for dyslipidemia, hypertension, diabetes, and acute coronary syndrome. The company is also pursuing the discovery of new medicines in the areas of glucose metabolic disorders, infectious diseases, cancer, bone and joint diseases, and immune disorders.

For more information, visit http://www.dsus.com.

About AZOR(TM)

AZOR was approved by the Food and Drug Administration (FDA) in September 2007 as a fixed combination of two antihypertensive drugs, the calcium channel blocker amlodipine and the angiotensin receptor blocker olmesartan medoxomil. AZOR is indicated for the treatment of hypertension, alone or with other antihypertensive agents. AZOR is not indicated for initial therapy of hypertension. AZOR is a convenient, once daily, single tablet combination of amlodipine, the number one prescribed calcium channel blocker (CCB) on the market, and olmesartan medoxomil. The combination of these two medications will give doctors a powerful new treatment option for patients with hypertension who need to reduce their blood pressure levels or who are uncontrolled on other medications.

In clinical trials, AZOR produced significant mean reductions in seated systolic and diastolic blood pressure in patients with hypertension. According to the pivotal registrational trial, AZOR 10/40 mg reduced systolic blood pressure an average of 30.1 mm Hg and the diastolic reading an average of 19.0 mm Hg. These results were in comparison with mean reductions of 19.7 mm Hg systolic/12.7 mm Hg diastolic for amlodipine 10 mg alone (placebo = 4.8/3.1 mm Hg). When compared to amlodipine 10 mg alone, AZOR 10/40 mg resulted in a 53 percent greater reduction in the mean change of systolic blood pressure.

IMPORTANT SAFETY INFORMATION ABOUT AZOR

USE IN PREGNANCY

When used in pregnancy during the s
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SOURCE Daiichi Sankyo, Inc.
Copyright©2007 PR Newswire.
All rights reserved

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