Navigation Links
DREAM and Sage Bionetworks tap the wisdom of the crowd to impact breast cancer prognosis
Date:4/17/2013

Two new reports issuing in Science Translational Medicine (STM) today showcase the potential of teams of scientists working together to solve increasingly complex medical problems. The results demonstrate that better predictors of breast cancer progression than those currently available can be rapidly evolved by running open Big Data Challenges such as The Sage Bionetworks/DREAM Breast Cancer Prognosis Challenge (BCC).

In breast cancer, a key undertaking is determining those patients whose disease is most likely to progress rapidly and therefore tailor the best course of treatment for them. Currently oncologists are using gene-expression based assays such as MammaPrint and Oncotype Dx, that are based on 10 year old science, and both do better with breast cancer risk prediction than models based only on clinical data.

Dr. Stephen Friend, the Founder of Sage Bionetworks and one of the organizers of the BCC reflects, Ten years ago, members of our research group used gene expression profiling to build one of the first breast cancer predictors. Mammaprint and Oncotype Dx were developed off of that but further improvement seems to have stalled. We wondered if running a Challenge like BCC would motivate lots ofdifferent groups to tackle this problem, some working collaboratively, and if that might be more fruitful than the current go it alone single researcher approach.

To push the envelope on all the innovations that could be incorporated into the BCC, Sage partnered with the DREAM Project, a visionary distributed systems biology group that has run 24 successful open computational challenges over the last five years.

DREAMs founder and leader, Dr. Gustavo Stolovitzky saw the BCC as an opportunity to, refocus our efforts to create a collaborative research environment that fosters a complementary way of doing science, which accelerates the pace of discovery with the goal of contributing to a fas
'/>"/>

Contact: Regina Warmoth
warmoth@sagebase.org
206-667-2102
Sage Bionetworks
Source:Eurekalert

Page: 1 2 3 4

Related medicine news :

1. Vall d’Hebron, VHIO and SOLTI head up an international dream team against breast cancer
2. Mechanism of breathing muscle paralysis in dreaming sleep identified
3. 4th AND GOAL: One Man’s Quest to Recapture his Dream, By Monte Burke
4. SU2C, Cancer Research Institute announce new immunology translational research dream team
5. Dreamcloud Productions Says New Sound-Reducing Sleep Mask May Be World’s Best Sleep Aid
6. Give the Gift of Great Food: The Hamptons & Long Island Homegrown Cookbook is a Perfect Holiday Gift under $30 for Food & Garden Lovers Dreaming of Homegrown Recipes
7. Contemporary Heaven Adds New Products to Dreamweavers Executive Range
8. New Dreamweavers Range of Cushions Introduced at Contemporary Heaven
9. The HearStrong Foundation Makes a HearStrong Champion’s Dreams Come True in New Orleans
10. Acting Out Dreams During Sleep May Signal Dementia
11. YourPleasurableSecrets.com, a leading retailer of Pipedream Products, Adult Toys & Novelties, is replenishing their lineup of adult movies Kay Parker has starred in.
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... Gabe’s Chemo Duck Program is pleased to announce ... ever created for kids with cancer. The Chemo Duck App, available ... filled with enjoyable games to help children of all ages living ... helps to keep kids entertained, educated and at ease while waiting ...
(Date:1/22/2015)... Blue Cross and Blue Shield of Minnesota (Blue Cross) wants ... “Live Fearless.” , The “Faces of Fearless” campaign ... how they or someone they know has faced a challenge, ... moment. By telling these types of stories through livefearlessmn.com, participants ...
(Date:1/22/2015)... 22, 2015 Thousand of GranuFlo lawsuits ... recalled its GranuFlo and NaturaLyte dialysis concentrates continue to ... U.S. District Court, District of Massachusetts, Bernstein Liebhard LLP ... Court has remanded a case filed by the state ...
(Date:1/22/2015)... January 22, 2015 A study ... Medicine flagship journal Medicine & Science in Sports ... exercise may help reduce gastrointestinal (GI) problems associated ... , Participants in the double-blind, placebo-controlled study took ...
(Date:1/22/2015)... 22, 2015 Payday lending practices in ... and cause financial distress to the states that permit ... Howard University’s Center on Race and Wealth. , While ... activity, payday loans at the same time substantially depress ...
Breaking Medicine News(10 mins):Health News:Chemo Duck Launches First App Ever Created for Kids with Cancer 2Health News:Chemo Duck Launches First App Ever Created for Kids with Cancer 3Health News:Blue Cross and Blue Shield of Minnesota to Showcase “Faces of Fearless” 2Health News:Court Overseeing Federal GranuFlo Lawsuits Remands Louisiana Claim Back to State Court, Bernstein Liebhard LLP Reports 2Health News:Court Overseeing Federal GranuFlo Lawsuits Remands Louisiana Claim Back to State Court, Bernstein Liebhard LLP Reports 3Health News:Court Overseeing Federal GranuFlo Lawsuits Remands Louisiana Claim Back to State Court, Bernstein Liebhard LLP Reports 4Health News:Study Shows Kyowa Hakko’s L-Citrulline May Help Reduce Gastrointestinal Injury During Strenuous Exercise 2Health News:Study Shows Kyowa Hakko’s L-Citrulline May Help Reduce Gastrointestinal Injury During Strenuous Exercise 3Health News:Howard University Spotlights the Economic Impact of Payday Lending in Southern States 2
... to a new study, patients with lung disease suffered more ... Texas studied a group of 200 patients with chronic obstructive ... steroids, to manage their condition, for a period of four ... received a placebo inhaler for the next five months. ...
... a report, giving radiation to surgical treatment for rectal ... of patients. But the findings suggest that the radiation ... quality of life by reducing the rate of cancer ... the rectum. ,In about 15% to 45% of ...
... to cook food. At first the cooked food was probably provided ... dominates our tables. Even now, centuries later, our taste buds do ... course arrives or at home as a filler,no meal is complete ... from the usual salads of cucumber - tomato - onion etc., ...
... cytomegalovirus could be involved in the development of colon ... colon cancer, the majority of cases arise for no ... have now exposed a link between viral infection and ... studies that show how human cytomegalovirus (CMV) can disrupt ...
... with high levels of hostility have a greater risk of ... Researchers in the US conducted a survey of 720 men, ... and the world around them.// They also asked them about ... weight to hip ratio. ,They found that among ...
... high blood pressure is a major factor accounting for ... well known that black people live, on average, six ... not complete //high school are at a similar disadvantage ... time, a study has identified the major health factors ...
Cached Medicine News:Health News:Keep fit with salads 2Health News:Keep fit with salads 3
(Date:1/23/2015)... 2015 Gem Pharmaceuticals announced today that the initial ... the Company,s Phase 2 clinical trial.  This open-label study ... compound, GPX-150 (an investigational medication), in approximately 30 adults ... Logo - http://photos.prnewswire.com/prnh/20150123/170966LOGO ...
(Date:1/23/2015)... , Jan. 23, 2015 Tianyin Pharmaceutical Inc. ... that specializes in the development and sale of patented ... and active pharmaceutical ingredients (API) today announced the business ... API operation. 1. Following the September 2014 ...
(Date:1/22/2015)... 2015  BiOptix is pleased to announce the appointment of ... Chemistry and Biochemistry. Scott joins the company after previous scientific ... throughout the course of his nearly 20 year career ... a nationally recognized thought leader in the biosensor field ...
Breaking Medicine Technology:Gem Pharmaceuticals Announces Enrollment of Initial Patients in its Phase 2 Clinical Trial to Assess the Efficacy and Safety of GPX-150 in Sarcoma Patients 2TPI's JCM Updates on Import Registration for International Clients 2TPI's JCM Updates on Import Registration for International Clients 3TPI's JCM Updates on Import Registration for International Clients 4BiOptix Expands Leadership Team with the Appointment of Dr. Scott Klakamp as Vice President of Chemistry and Biochemistry 2
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
Medicine Products: