Navigation Links
DNDi receives the BBVA Foundation Frontiers of Knowledge Award in Development Cooperation
Date:6/19/2013

e it is supposed to cure. The new treatment is already available in the twelve African countries which account for 99% of reported sleeping sickness cases.

DNDi is also working with partners on two new chemical entities for this disease: oxaborole SCYX-7158 and fexinidazole. The first is an oral compound which is currently concluding Phase I clinical studies, while fexinidazole, also an oral treatment, began Phase II/III studies in the Democratic Republic of the Congo and Central African Republic in October 2012.

"A safe, effective, oral-only treatment would simplify the way the disease is managed," Pcoul explains, "as well as supporting the WHO's target to eliminate sleeping sickness by 2020."

Leishmaniasis and Chagas

DNDi is also about to start Phase II studies testing efficacy and safety on the use of fexinidazole in visceral leishmaniasis patients in East Africa.

Ten years ago, the standard treatment for visceral leishmaniasis was a month-long course of painful daily injections, a treatment schedule that is difficult to manage in poorly equipped health centers in the remote areas where the disease is found. The combined therapy delivered by DNDi has already shortened the treatment duration to 17 days, but the goal remains to come up with an oral treatment.

In the case of Chagas disease, a decade ago there were no pediatric formulations. DNDi's dosage form for children up to the age of two is oral, inexpensive, and easy-to-use. It is also designed for home administration: an important pro-compliance factor in what is a lengthy two-month treatment.

Another oral drug, E1224, is currently being tested on adult patients in Bolivia. "If successful," Pcoul says, "this drug could be the oral, easy-to-use, affordable and safe treatment option that Chagas patients need and deserve."

These ongoing projects are joined by an early-stage pipeline of twelve entirely new chemical entities.

'/>"/>
Contact: Violaine Dällenbach
vdallenbach@dndi.org
41-794-241-474
Drugs for Neglected Diseases Initiative
Source:Eurekalert

Page: 1 2 3 4 5

Related medicine news :

1. Loyola Cancer Center receives Outstanding Achievement Award
2. MU receives national award for using mind-body approach to improve health
3. Neuropsychologist receives University of Houstons highest faculty honor
4. Boston researcher, surgical oncologist receives national award
5. LA BioMed receives Grand Challenges Explorations grant
6. Lawson researcher receives 1 of first-ever Pfizer Psychiatry Research Awards
7. Dr. Arthur Slutsky, vice-president of research at St. Michaels, receives lifetime award
8. UC San Diego Superfund Research Program receives $15 million grant renewal
9. Markey receives $6.25 million to study deadly blood and bone marrow disease
10. Feola, at University of Kentucky, receives NIH grant to study cystic fibrosis
11. UC Santa Barbaras Kavli Institute receives 2 grants to explore interface of physics and biology
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/20/2014)... Angeldress.co.uk, the distinguished wedding dress manufacturer ... dress fans. The company has recently updated its official ... the holiday season, Angeldress Blog has recommended ... , Angeldress.co.uk prides itself in offering a huge selection ... All the company’s outfits are very carefully selected based ...
(Date:12/20/2014)... York, NY (PRWEB) December 20, 2014 The ... has caused quite a stir, not only in Hollywood, but ... on December 18th , the ripples of that attack are ... executives’ very jobs at risk. But they are not ... correspondences exposed could be in for some embarrassing times ahead, ...
(Date:12/20/2014)... Xarelto bleeding lawsuits filed by men ... and other serious side effects will be consolidated in ... coordinated pretrial proceedings, Wright & Schulte LLC reports. The ... order Friday to transfer 21 Xarelto lawsuits and over ... to the Louisiana district court for coordination by Judge ...
(Date:12/20/2014)... Today, Balfleet.com, one of the most outstanding dressmakers in ... on its Mother of the Bride Dresses ... bride dresses from Balfleet.com feature gorgeous looks and delicate ... pride in providing high quality dresses to its clients ... on our mother of the bride dresses, and we ...
(Date:12/19/2014)... Sweetdressy.com , a leading wedding dress manufacturer ... of cheap prom dresses for ladies worldwide. The prom ... and clients can buy these dresses at the website ... cool cuts and delicate craftsmanship, and most of them ... Discount shipping costs are available for all of their ...
Breaking Medicine News(10 mins):Health News:Trendy Professional Wedding Apparel Recommended by Angeldress Blog 2Health News:Sony Pictures Hack Perfect Example of the Reach a Single Cyber Attack Can Have 2Health News:Sony Pictures Hack Perfect Example of the Reach a Single Cyber Attack Can Have 3Health News:Sony Pictures Hack Perfect Example of the Reach a Single Cyber Attack Can Have 4Health News:Sony Pictures Hack Perfect Example of the Reach a Single Cyber Attack Can Have 5Health News:Xarelto Bleeding Lawsuits Consolidated To Louisiana Federal Court For Multi-District Litigation Reports Wright & Schulte LLC 2Health News:Xarelto Bleeding Lawsuits Consolidated To Louisiana Federal Court For Multi-District Litigation Reports Wright & Schulte LLC 3Health News:Xarelto Bleeding Lawsuits Consolidated To Louisiana Federal Court For Multi-District Litigation Reports Wright & Schulte LLC 4Health News:Balfleet.com is Offering 50%-70% Off of its Mother of the Bride Dresses 2Health News:Cheap Prom Dresses Online Now at Sweetdressy.com 2
... in midlife underreport the number of hot flashes that they ... are linked to poor verbal memory, according to a study ... The study is published online and will appear in the ... is the first study to explore the relationship between objectively ...
... 16 The American,Association for Homecare (AAHomecare) applauded ... that will delay for at least 18 months ... home,medical equipment and services. The bill, H.R. 6252, ... of 2008.", The competitive acquisition or "competitive ...
... as surgery and pharmaceuticals were important to medicine in the ... the 21st century,and biofeedback is an important component of Behavioral ... Basmajian, Member ... One of the World,s Leading Sport,Psychologists that trained Canada,s top ...
... can lessen the cholesterol-lowering drugs, effectiveness , , MONDAY, June ... production of one protein helps explain why some people ... researchers report. , Statins include blockbuster medications such as ... as HMGCR, plays a critical role in production of ...
... where, but calls it ,most fruitful, lead in ongoing ... News) -- Although a U.S. government investigation into ... for the contamination, health officials said Monday they are ... nine cases in one location. , "The cluster ...
... Staff, and 7 other HFI usability, experts speak ... research topics including, ,Who are We ... YORK, June 16 Human Factors International (HFI),the ... "platinum",sponsorship of the 2008 Usability Professionals, Association International,Conference. ...
Cached Medicine News:Health News:Hot flashes underreported and linked to forgetfulness 2Health News:American Association for Homecare Applauds Bill to Delay the Flawed Medicare Bidding Program for Home Medical Equipment 2Health News:American Association for Homecare Applauds Bill to Delay the Flawed Medicare Bidding Program for Home Medical Equipment 3Health News:Biofeedback Workshops & Distance Learning Offer Credits and Training Options 2Health News:Research Shows Why Statins Don't Work for Everyone 2Health News:FDA Narrowing Tainted Tomato Probe to One Cluster 2Health News:FDA Narrowing Tainted Tomato Probe to One Cluster 3Health News:Human Factors International Sponsors Usability Professionals' Association (UPA) 2008 International Conference 2Health News:Human Factors International Sponsors Usability Professionals' Association (UPA) 2008 International Conference 3
(Date:12/17/2014)... , The new Dompé website aims ... the biopharmaceutical Group,s national and international clinical research activities ... launched institutional website that is receiving accolades from all over ... chapter in the fascinating story of Drug Discovery   , ... on the world of clinical research, ranging from information for ...
(Date:12/17/2014)... N.J. , Dec. 17, 2014  IGI Laboratories, ... today the closing of its offering of $125 million ... 2019 (the "Notes").  The Notes were offered and sold ... under the Securities Act of 1933, as amended (the ... a fixed rate of 3.75% per year, payable semiannually ...
(Date:12/17/2014)... RALEIGH, N.C. , Dec. 17, ... (CTMC), and Integrated Clinical Trial Services, LLC (ICTS), ... for clinical trials announce that they have formed ... Services (i-CTMS). i-CTMS will provide a broad range ... biotechnology and medical device companies. i-CTMS ...
Breaking Medicine Technology:Dompé Offers a New "Window" on the World of Scientific Research, with the http://www.dompetrials.com Website, Dedicated to Clinical Trials 2Dompé Offers a New "Window" on the World of Scientific Research, with the http://www.dompetrials.com Website, Dedicated to Clinical Trials 3IGI Laboratories Announces Closing of $125 Million of 3.75% Convertible Senior Notes Due 2019 2IGI Laboratories Announces Closing of $125 Million of 3.75% Convertible Senior Notes Due 2019 3IGI Laboratories Announces Closing of $125 Million of 3.75% Convertible Senior Notes Due 2019 4Integrated Clinical Trial Services and Clinical Trial Marketing Communications Form Joint Venture 2Integrated Clinical Trial Services and Clinical Trial Marketing Communications Form Joint Venture 3
... Oct. 10, 2011 Complementary and alternative medical (CAM) ... in the United States, especially among older patients and ... can have serious and potentially harmful side effects when ... to a review article in the Journal of ...
... 10, 2011 Groupe Athena, Inc. (Pink sheets GATA.PK) announced ... September 30, 2011 which generated pretax earnings of $1,566,906, or ... same period. With the most recent strong quarter, trailing twelve ... record quarterly revenue was significant in that it equaled nearly ...
Cached Medicine Technology:Herbal Supplements May Cause Dangerous Drug Interactions in Orthopaedic Surgery Patients 2Herbal Supplements May Cause Dangerous Drug Interactions in Orthopaedic Surgery Patients 3Herbal Supplements May Cause Dangerous Drug Interactions in Orthopaedic Surgery Patients 4Groupe Athena, Inc. Reports Record First Quarter Revenues 2Groupe Athena, Inc. Reports Record First Quarter Revenues 3
4.625 inches, curved blade 4 mm....
Alvis foreign body spud 4 3/4 inches, oval curette 1 x 3 mm with fine point....
DIX foreign body spud 4 3/4 inches, 1.7 x 15 mm blade....
In reversible handle for removing foreign bodies....
Medicine Products: