Navigation Links
DNA vaccine against multiple sclerosis appears safe, potentially beneficial
Date:8/13/2007

and produced beneficial antigen-specific immune changes, the authors write. These changes included a reduction in the number of cytokine-producing CD4+ T cells (a type of white blood cell) specifically targeting myelin proteins. This reduction was found in the blood as well as in the cerebrospinal fluid of three patients who voluntarily underwent lumbar puncture after completing the course of BHT-3009. Atorvastatin did not appear to provide additional benefit.

There were no increases in clinical relapses, disability, drug-associated laboratory abnormalities, adverse events or the number and volume of contrast-enhancing [visible on MRI] lesions on brain MRI with BHT-3009 treatment compared with placebo, the authors write. In fact, there was a trend toward a decrease in the number and volume of contrast-enhancing lesions in the brain in patients treated with BHT-3009 compared with placebo.

Based on these results, a phase 2b triala randomized clinical trial in approximately 290 patientsof BHT-3009 is already under way. If successful in MS, antigen-specific DNA vaccines can be developed for prevention or treatment of related diseases, such as type 1 diabetes mellitus, systemic lupus erythematosus, rheumatoid arthritis and myasthenia gravis, the authors conclude.


'/>"/>

Contact: Susan Thomas
415-352-6262
JAMA and Archives Journals
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Vaccine to quit smoking?
2. First Vaccine Designed for Africa Cleared for Testing in Humans
3. New hope for cancer victims – will vaccine cure the deadly bug
4. Vaccine for Alzheimer’s diseas
5. New vaccine helps allergy and asthma patients
6. Man against HIV – new vaccine ready for human trials
7. New vaccine helps allergy and asthma patients
8. Development of AIDS vaccine -- Chiron Corp in talks with four Indian cos
9. HIV did not arise from polio vaccine
10. Double impact vaccine
11. Health Officials Recommend Flu Vaccine
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/20/2014)... key genes linked to why some people have a ... study released today that will be presented at the ... April 26 to May 3, 2014. , "Our ... way to understand pain and why different individuals have ... MD, MPH, with Proove Biosciences and a member of ...
(Date:4/18/2014)... Harvard neuroscientists have made a discovery that turns 160 ... electrical insulating material long known to be essential for ... nerve cells, is not as ubiquitous as thought, according ... of the Harvard Stem Cell Institute (HSCI) and the ... collaboration with Professor Jeff Lichtman, of Harvard,s Department of ...
(Date:4/18/2014)... A new study in the American Journal of ... searches reveals a recurring pattern that could be leveraged ... from San Diego State University, the Santa Fe Institute, ... Google searches (searches that included the term healthy and ... U.S. from 2005 to 2012. They found that on ...
(Date:4/17/2014)... first genetic variant specifically associated with the risk ... 10-15 per cent of all breast cancer cases. ... cancer sub-type, called invasive lobular carcinoma, gives researchers ... particular kind of breast cancer, which can be ... (Thursday) in the journal PloS Genetics , ...
(Date:4/17/2014)... California, San Diego School of Medicine report that older ... recent major loss are more likely to be compassionate ... is published in this month,s issue of the ... behaviors are associated with better health and well-being as ... to improve the outcomes of individuals whose deficits in ...
Breaking Medicine News(10 mins):Health News:Low tolerance for pain? The reason may be in your genes 2Health News:Finding turns neuroanatomy on its head 2Health News:Finding turns neuroanatomy on its head 3Health News:New research shows people are thinking about their health early in the week 2Health News:First genetic link discovered to difficult-to-diagnose breast cancer sub-type 2Health News:First genetic link discovered to difficult-to-diagnose breast cancer sub-type 3Health News:The ilk of human kindness 2
... Cancer researchers have discovered a previously unknown type of ... that may lead to better insight about environmental exposure ... the journal Genome Research by researchers at ... Cancer Hospital and Richard J. Solove Research Institute (OSUCCC-James), ...
... In a promising development for cancer patients in New ... at Hackensack University Medical Center announced today that it ... to acquire an innovative system that enables a radically ... known as the TrueBeam system. The new radiotherapy system ...
... the 2008-09 Gaza War gave Tel Aviv University researchers a ... In a new study in the American Journal ... of Psychology reports that people confronted with acute stress -- ... of becoming more vigilant. This research overturns accepted convention and ...
... HealthDay Reporter , FRIDAY, July 16 (HealthDay News) -- High ... cost of wearing them is even steeper than the sky-high ... aching feet and a variety of foot deformities, years of ... muscles and tendons, according to a study by researchers in ...
... Institute of Technology not only involves its students in ... many innovations. An example of recently licensed university technology ... neuroscientists in the laboratory. Associate Professor Nasri Nesnas ... CDNI-Glu, a commonly used laboratory research tool. Most often, ...
... Multiple myeloma is one of the most common blood cancers, ... study from Uppsala University, researchers now present a conceptually new ... study was done in collaboration with Vrije Universitet Brussels and ... PLoS ONE . Using large cohorts of myeloma ...
Cached Medicine News:Health News:Breast cancer cells regulate multiple genes in response to estrogen-like compounds 2Health News:John Theurer Cancer Center first cancer center in N.J. to acquire new radiotherapy system 2Health News:John Theurer Cancer Center first cancer center in N.J. to acquire new radiotherapy system 3Health News:Battlefield psychologists investigate stress in combat and after 2Health News:Those To-Die-For High Heels May Alter Anatomy 2Health News:Those To-Die-For High Heels May Alter Anatomy 3
(Date:1/15/2014)... , Jan. 15, 2014 ... research report is available in its ... Markets and Technologies for Advanced Drug ... of Administration ...
(Date:1/15/2014)...  A novel wearable injector slightly larger than an Oreo cookie ... self-inject prescription drugs in the large doses required to treat ... deficiencies, and genetic disorders.  An emerging biologic ... according to analysts.   Many of these drugs will require a ...
(Date:1/14/2014)... AUSTIN, Texas , Jan. 14, 2014  Luminex Corporation (Nasdaq: ... report results for the fourth quarter of 2013 on Monday, ... scheduled for release after the close of trading. ... a conference call to discuss the operating highlights and financial ...
Breaking Medicine Technology:Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 2Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 3Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 4Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 5Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 6Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 7Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 8Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 9Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 10Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 11Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 12Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 13Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 14Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 15Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 16Enable Injections Presents A New Class of Injectors for Drug Delivery at PEPTalk, Drug Delivery Partnership Meetings 2Luminex Corporation Fourth Quarter Earnings Release Scheduled for February 3, 2014 2Luminex Corporation Fourth Quarter Earnings Release Scheduled for February 3, 2014 3
... YORK, June 8, 2011 Reportlinker.com announces ... available in its catalogue: ... http://www.reportlinker.com/p0487169/Novo-Nordisk-A/S-PharmaVitae-Profile.html?utm_source=prnewswire&utm_medium=pr&utm_campaign=NoCategory ... the historical and forecast performance for Novo ...
... 2011 Reportlinker.com announces that a ... in its catalogue: ... Analysis, Competitive Landscape and Market Forecasts ... http://www.reportlinker.com/p0548450/Hip-Replacement-Implants---Global-Pipeline-Analysis-Competitive-Landscape-and-Market-Forecasts-to-2017.html?utm_source=prnewswire&utm_medium=pr&utm_campaign=NoCategory Hip Replacement ...
Cached Medicine Technology:Novo Nordisk A/S: PharmaVitae Profile 2Reportlinker Adds Hip Replacement Implants - Global Pipeline Analysis, Competitive Landscape and Market Forecasts to 2017 2Reportlinker Adds Hip Replacement Implants - Global Pipeline Analysis, Competitive Landscape and Market Forecasts to 2017 3
... allows braided suture to be used in ... may be used with any type or ... with anchors or screws (including suture pre-assembled ... Relay can be passed through any conventional ...
The 4mm diameter Revo suture anchor is designed primarily for arthroscopic and open rotator cuff repair. Additional applications include other shoulder repair procedures, as well as use in knees and ...
... sutureless fixation device offers superior fixation ... implant firmly reattaches soft tissue to ... CuffTack is indicated for the fixation ... to bone. The implant is composed ...
... to use system can be used for ... is pre-packaged on a sterile disposable inserter. ... simple and reproducible insertion of the anchor ... (I.S.S.™) Eyelet Design allows for the two ...
Medicine Products: