Navigation Links
DNA Test May Detect Immune Disorder in Infants
Date:12/8/2009

State screening programs identify newborns with T-cell lymphopenia, researchers say

TUESDAY, Dec. 8 (HealthDay News) -- A DNA test can identify newborns with T-cell lymphopenia, a blood disorder that affects the immune system, U.S. researchers say.

Infants with T-cell lymphopenia -- an abnormally low level of white blood cells -- often appear normal and have no family history of immunodeficiency.

"Consequently, many infants with severe T-cell deficiencies are not identified until life-threatening infections occur," wrote Dr. John M. Routes, of the Medical College of Wisconsin and Children's Research Institute in Milwaukee, and colleagues.

Early diagnosis greatly improves the long-term prognosis of infants with T-cell lymphopenia. The researcher also noted that some vaccines recommended in early infancy can cause serious infections in infants with T-cell lymphopenia. Early detection of the immune system disorder could help prevent such infections.

In the new study, all infants born in Wisconsin in 2008 were screened for T-cell lymphopenia using a test that determines the number of T-cell receptor excision circles (TRECs) in DNA extracted from dried blood spots on newborn blood screening cards.

Of the 71,000 infants screened, 17 of the infants of at least 37 weeks' gestation had at least one abnormal TREC test result. Samples from 11 of those 17 infants were analyzed to count T cells. Eight were found to have T-cell lymphopenia and evaluated by a clinical immunologist, the study authors reported.

The findings, published in the Dec. 9 issue of the Journal of the American Medical Association, demonstrate the value of state screening programs for T-cell lymphopenia, the researchers wrote.

More information

The U.S. National Institute of Child Health and Human Development explains primary immunodeficiency.



-- Robert Preidt



SOURCE: Journal of the American Medical Association, news release, Dec. 8, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Mayo Clinic researchers discover new diagnostic test for detecting infection in prosthetic joints
2. Eye-staining technique offers early detection for dry eye syndrome
3. Scientists detect presence of marburg virus in african fruit bats
4. Insurance Impacts Laryngeal Cancer Detection
5. New technique detects specific chromosomal damage, may indicate lung cancer risk
6. Blood-flow detector software show promise in preventing brain damage
7. Purdue researchers develop technology to detect cancer by scanning surface veins
8. Novel virus detection identifies new viruses in study of respiratory infections and asthma attacks
9. Drug Detection Kits Manufactured By IDenta Corp. Shown During French Television Broadcast (at TF1) - Product Aids French Police In Bust of 600 Kilograms Of Cocaine
10. Implantable device designed to detect, stop seizures under study at MCG
11. Liver cancer marker could yield blood test for early detection
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/6/2016)... ... 06, 2016 , ... The Price Agency in Birmingham, AL ... assist the people of their local community. The agency pledges to select a ... Their desire is to bring awareness to important local causes with fundraising and ...
(Date:5/6/2016)... ... May 06, 2016 , ... The joy associated with Mother’s Day is mixed with ... neonatal intensive care units (NICUs) across the country. For the first time ever, the ... honor these women who spend their Mother’s Day beside a crib surrounded by lifesaving equipment ...
(Date:5/6/2016)... ... ... US Sports Camps has collaborated with State Rugby Organization (SRO), Rugby Oregon, ... Employing world-class rugby figures, including former Team USA players and college coaches, this program ... match play, fitness and more. , “US Sports Camps is honored to be working ...
(Date:5/6/2016)... ... May 06, 2016 , ... Bluvault ( Bluvault Inc. ... offering for global clients of Coupa ( Coupa Software ) and other Cloud ... is a key component in the suite of innovative implementation services offered by ...
(Date:5/6/2016)... ... May 06, 2016 , ... ... reduce fat areas around the body, is the most popular among body sculpting ... released make perfect sense to cosmetic surgeon Dr. Richard Buckley, medical director of ...
Breaking Medicine News(10 mins):
(Date:5/4/2016)... According to market research "Global Computed ... to 2022 - Industry Insights by Slice Type (High, Mid ... by P&S Market Research, the global computed tomography market ... is expected to grow at a CAGR of 5.0% during ... is expected to witness the faster growth, CAGR of 5.3%, ...
(Date:5/4/2016)... , May 4, 2016 ... of the  "Global Acute Ischemic Stroke Market ... to their offering.       (Logo: ... Global Acute Ischemic Stroke Market and Competitive ... Acute Ischemic Stroke pipeline products, Acute Ischemic ...
(Date:5/3/2016)... , May 3, 2016 BioNovus Innovations ... Institute for Advancing Medical Innovation (IAMI) today announced ... drugs, diagnostics and medical devices. An ... with rights to license, develop and commercialize medical ... "This partnership represents a significant advance ...
Breaking Medicine Technology: