Navigation Links
DNA Test May Detect Immune Disorder in Infants
Date:12/8/2009

State screening programs identify newborns with T-cell lymphopenia, researchers say

TUESDAY, Dec. 8 (HealthDay News) -- A DNA test can identify newborns with T-cell lymphopenia, a blood disorder that affects the immune system, U.S. researchers say.

Infants with T-cell lymphopenia -- an abnormally low level of white blood cells -- often appear normal and have no family history of immunodeficiency.

"Consequently, many infants with severe T-cell deficiencies are not identified until life-threatening infections occur," wrote Dr. John M. Routes, of the Medical College of Wisconsin and Children's Research Institute in Milwaukee, and colleagues.

Early diagnosis greatly improves the long-term prognosis of infants with T-cell lymphopenia. The researcher also noted that some vaccines recommended in early infancy can cause serious infections in infants with T-cell lymphopenia. Early detection of the immune system disorder could help prevent such infections.

In the new study, all infants born in Wisconsin in 2008 were screened for T-cell lymphopenia using a test that determines the number of T-cell receptor excision circles (TRECs) in DNA extracted from dried blood spots on newborn blood screening cards.

Of the 71,000 infants screened, 17 of the infants of at least 37 weeks' gestation had at least one abnormal TREC test result. Samples from 11 of those 17 infants were analyzed to count T cells. Eight were found to have T-cell lymphopenia and evaluated by a clinical immunologist, the study authors reported.

The findings, published in the Dec. 9 issue of the Journal of the American Medical Association, demonstrate the value of state screening programs for T-cell lymphopenia, the researchers wrote.

More information

The U.S. National Institute of Child Health and Human Development explains primary immunodeficiency.



-- Robert Preidt



SOURCE: Journal of the American Medical Association, news release, Dec. 8, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Mayo Clinic researchers discover new diagnostic test for detecting infection in prosthetic joints
2. Eye-staining technique offers early detection for dry eye syndrome
3. Scientists detect presence of marburg virus in african fruit bats
4. Insurance Impacts Laryngeal Cancer Detection
5. New technique detects specific chromosomal damage, may indicate lung cancer risk
6. Blood-flow detector software show promise in preventing brain damage
7. Purdue researchers develop technology to detect cancer by scanning surface veins
8. Novel virus detection identifies new viruses in study of respiratory infections and asthma attacks
9. Drug Detection Kits Manufactured By IDenta Corp. Shown During French Television Broadcast (at TF1) - Product Aids French Police In Bust of 600 Kilograms Of Cocaine
10. Implantable device designed to detect, stop seizures under study at MCG
11. Liver cancer marker could yield blood test for early detection
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/23/2017)... ... 23, 2017 , ... "ProRandom is a set of camera tools that allow video editors to ... Cut Pro X," said Christina Austin - CEO of Pixel Film Studios. , With ... with video footage. ProRandom works by using a virtual camera to create the illusion ...
(Date:1/23/2017)... ... January 23, 2017 , ... ... (OREF), in partnership with the American Society of Anesthesiologists® (ASA®), the Foundation ... the American Academy of Orthopaedic Surgeons (AAOS) and the Cigna Foundation, encourages ...
(Date:1/23/2017)... (PRWEB) , ... January 23, 2017 , ... “The Inn at the Mill”: a ... unexpected fears in her quest to become happy and content. , “The Inn at ... Pennsylvania, has also lived in Germany and Vermont and is now living in Berks County ...
(Date:1/23/2017)... ... January 23, 2017 , ... ... programs and resources at seafoodnutrition.org/programs and seafoodnutrition.org/resources to assist in teaching communities ... These resources have been developed for use by nutrition educators and influencers ...
(Date:1/23/2017)... , ... January 23, 2017 , ... “Some Infallible Characteristics ... the Father. “Some Infallible Characteristics of Christ” is the creation of published author, Rev. ... a Baptist Church for thirteen years, a preacher for over nineteen, a pastor for ...
Breaking Medicine News(10 mins):
(Date:1/23/2017)... 23, 2017 LifeVac, the revolutionary device that ... and prevented choking deaths, welcomes Steve Way , ... LifeVac team as Official Spokesperson. "We ... team," said Arthur Lih , Founder and CEO ... and his mission to raise awareness about the physically ...
(Date:1/23/2017)... Jan 23, 2017 Research and Markets has announced ... Trends - Product - Forecast to 2025" report to their offering. ... Report Highlights: ... market trends to identify the investment opportunities Market forecasts ... Key market trends across the business segments, Regions and Countries ...
(Date:1/23/2017)... -- Stock-Callers.com today presents the following Generic Drugs ... ), Sophiris Bio Inc. (NASDAQ: SPHS ), Momenta ... Inc. (NASDAQ: AGRX ). These companies are part ... trade on Friday, January 20 th , 2017, with the ... health care companies in the S&P 500 also were sinking ...
Breaking Medicine Technology: