Navigation Links
DNA Test May Detect Immune Disorder in Infants
Date:12/8/2009

State screening programs identify newborns with T-cell lymphopenia, researchers say

TUESDAY, Dec. 8 (HealthDay News) -- A DNA test can identify newborns with T-cell lymphopenia, a blood disorder that affects the immune system, U.S. researchers say.

Infants with T-cell lymphopenia -- an abnormally low level of white blood cells -- often appear normal and have no family history of immunodeficiency.

"Consequently, many infants with severe T-cell deficiencies are not identified until life-threatening infections occur," wrote Dr. John M. Routes, of the Medical College of Wisconsin and Children's Research Institute in Milwaukee, and colleagues.

Early diagnosis greatly improves the long-term prognosis of infants with T-cell lymphopenia. The researcher also noted that some vaccines recommended in early infancy can cause serious infections in infants with T-cell lymphopenia. Early detection of the immune system disorder could help prevent such infections.

In the new study, all infants born in Wisconsin in 2008 were screened for T-cell lymphopenia using a test that determines the number of T-cell receptor excision circles (TRECs) in DNA extracted from dried blood spots on newborn blood screening cards.

Of the 71,000 infants screened, 17 of the infants of at least 37 weeks' gestation had at least one abnormal TREC test result. Samples from 11 of those 17 infants were analyzed to count T cells. Eight were found to have T-cell lymphopenia and evaluated by a clinical immunologist, the study authors reported.

The findings, published in the Dec. 9 issue of the Journal of the American Medical Association, demonstrate the value of state screening programs for T-cell lymphopenia, the researchers wrote.

More information

The U.S. National Institute of Child Health and Human Development explains primary immunodeficiency.



-- Robert Preidt



SOURCE: Journal of the American Medical Association, news release, Dec. 8, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Mayo Clinic researchers discover new diagnostic test for detecting infection in prosthetic joints
2. Eye-staining technique offers early detection for dry eye syndrome
3. Scientists detect presence of marburg virus in african fruit bats
4. Insurance Impacts Laryngeal Cancer Detection
5. New technique detects specific chromosomal damage, may indicate lung cancer risk
6. Blood-flow detector software show promise in preventing brain damage
7. Purdue researchers develop technology to detect cancer by scanning surface veins
8. Novel virus detection identifies new viruses in study of respiratory infections and asthma attacks
9. Drug Detection Kits Manufactured By IDenta Corp. Shown During French Television Broadcast (at TF1) - Product Aids French Police In Bust of 600 Kilograms Of Cocaine
10. Implantable device designed to detect, stop seizures under study at MCG
11. Liver cancer marker could yield blood test for early detection
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/26/2016)... ... 2016 , ... Brent Kasmer, a legally blind and certified personal trainer is helping to develop ... The fitness app plans to fix the two major problems leading the fitness industry today:, ... all type program , They don’t eliminate all the reasons people quit their ...
(Date:6/25/2016)... Austin, TX (PRWEB) , ... June 25, 2016 , ... ... Fellow of the American College of Mohs Surgery and to Dr. Russell Peckham for ... popular and highly effective treatment for skin cancer. The selective fellowship in Mohs Micrographic ...
(Date:6/25/2016)... TX (PRWEB) , ... June 25, 2016 , ... ... the United States, named Dr. Sesan Ogunleye, as the Medical Director of its new ... the facility Medical Director of our new Mesquite location,” said Dr. James M. Muzzarelli, ...
(Date:6/25/2016)... ... June 25, 2016 , ... On Friday, June 10, Van Mitchell, ... at Work award to iHire in recognition of their exemplary accomplishments in worksite health ... annual Maryland Workplace Health & Wellness Symposium at the BWI Marriott in Linthicum Heights. ...
(Date:6/24/2016)... ... June 24, 2016 , ... Those who have experienced traumatic events may ... to unhealthy avenues, such as drug or alcohol abuse, as a coping mechanism. To ... for healthy coping following a traumatic event. , Trauma sufferers tend to feel a ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... CAMBRIDGE, Mass. , June 24, 2016 /PRNewswire/ ... the Spaulding Rehabilitation Network,s Dean Center for ... of Physical Medicine and Rehabilitation, MIT Hacking Medicine, ... Center for Innovation, today announced the five finalists ... Hackathon for Lyme disease.  More than 100 scientists, ...
(Date:6/24/2016)... Dehaier Medical Systems Ltd. (NASDAQ: DHRM ) ... medical devices and wearable sleep respiratory products in ... with Hongyuan Supply Chain Management Co., Ltd. (hereinafter referred ... to develop Dehaier,s new Internet medical technology business. ... Hongyuan Supply Chain,s sales platform to reach Dehaier,s dealers ...
(Date:6/24/2016)... , June 24, 2016   Pulmatrix, Inc ., ... developing innovative inhaled drugs, announced today that it was ... Investments reconstituted its comprehensive set of U.S. and ... "This is an important milestone for Pulmatrix," said Chief ... shareholder awareness of our progress in developing drugs for ...
Breaking Medicine Technology: