Navigation Links
DNA Test May Cut Hospitalizations Caused by Blood Thinner
Date:3/16/2010

Determining sensitivity can prevent bleeding, clotting problems, study shows

TUESDAY, March 16 (HealthDay News) -- A simple genetic test that helps doctors determine the best dose of the blood-thinner drug warfarin for individual patients could reduce hospitalizations by one-third during the early dose-adjustment phase, a new study has found.

The test identifies variations in two genes that strongly influence sensitivity to warfarin (Coumadin), which is used to prevent blood clots in people with high-risk conditions, such as atrial fibrillation, or after surgery to replace a heart valve.

"Genetic testing is a tool clinicians can use to more accurately predict the best warfarin dose early on," Dr. Robert S. Epstein, chief medical officer and president of the Medco Research Institute in Franklin Lakes, N.J., said in a news release from the American College of Cardiology. "Patients may get to a stable dose more quickly and, therefore, have a lower risk of negative outcomes, such as excess bleeding or unwanted blood clotting."

The findings were to be presented Tuesday at the college's annual meeting in Atlanta.

The study included 896 people who, shortly after beginning warfarin therapy, gave a blood sample or cheek swab that was analyzed for expression of two genes -- CYP2C9 and VKORC1 -- that revealed sensitivity to warfarin. People with high sensitivity were put on a reduced dose of warfarin and had frequent blood tests. People with low sensitivity were given a higher dose of warfarin.

During the first six months that they took warfarin, those who underwent genetic testing were 31 percent less likely to be hospitalized for any reason and 29 percent less likely to be hospitalized for bleeding or thromboembolism than were a group that did not have genetic testing.

Epstein said that the cost of the genetic testing -- $250 to $400 -- would be justified by reduced hospitalization costs.


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Page: 1 2

Related medicine news :

1. Minnesota Department of Health Report: Nearly 6,000 Hospitalizations for COPD in 2007
2. Air pollution linked to hospitalizations for pneumonia in seniors
3. Outpatient Palliative Care Reduces Hospitalizations, Which Impact Costs, While Improving Quality of Life for Seniors and Family Caregivers - New Study in American Journal of Managed Care
4. Swine Flu May Bring Surge in Hospitalizations
5. Fertility Treatment Twins More at Risk for Hospitalizations
6. New Data Demonstrate RISPERDAL(R) CONSTA(R) (Risperidone) Long-Acting Treatment May Improve Health Outcomes and Reduce Hospitalizations in Patients with Schizophrenia
7. Avalere Shows Home Health Interventions Associated with Lower Medicare Spending and Re-Hospitalizations for Patients With Chronic Illness
8. American Heart Association Leads Efforts to Reduce Preventable Deaths and Rehospitalizations for Heart Failure Patients
9. High Rate of Rehospitalizations Costing Billions
10. Global warning: Hotter days, increased hospitalizations for respiratory problems
11. Home Care Tips for Reducing the Risk of Childhood Hospitalizations Due to Asthma
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/24/2014)... Philadelphia, Pa. (April 24, 2014) - Contact lenses coated with ... contact lens-related infections, reports a study in Optometry ... American Academy of Optometry . The journal is published ... Wolters Kluwer Health . , Studies in animals and ... with the antimicrobial peptide melimine, according to the new research ...
(Date:4/24/2014)... be boring and irrelevant, could offer an alternative to ... Dr Milena Furtado, and her team from the Australian ... heart cell fibroblast is a close relative to a ... , In research published today in Circulation Research ... unique cells due to their genetic program, and will ...
(Date:4/24/2014)... in the world to discover a gene mutation in ... Ameloblastoma is an odontogenic tumour with a high tendency ... in the posterior of the lower jaw. Ameoloblastomas are ... the jaws as well as loss of several teeth. ... surgery and the recurrence of ameloblastoma, but finding such ...
(Date:4/24/2014)... by a scientist at the University of York reveals ... the development of the nervous system may also play ... A research team, led by Dr Will Brackenbury, ... Biology at York, has studied how voltage-gated sodium channels ... are found in the membranes of excitable cells, such ...
(Date:4/23/2014)... Spokane have developed a new way to detect ... the wheel. , Their recently patented technology is ... in drowsy driversand offers an affordable and more ... detection systems. , Van Dongen"Video-based systems that use ... out of its lane are cumbersome and expensive," ...
Breaking Medicine News(10 mins):Health News:Study supports safety of antimicrobial peptide-coated contact lenses 2Health News:Study supports safety of antimicrobial peptide-coated contact lenses 3Health News:Boring cells could hold the key to heart disease 2Health News:Breast cancer replicates brain development process 2Health News:WSU innovation improves drowsy driver detection 2
... MYL ),announced today the appointment of Daniel ... as a member of the company,s senior leadership ... Crookshank is,responsible for all investment community communication as ... that proactively promote Mylan to,the investment community., ...
... Ala., July 21 Health,Care Systems, Inc. (HCS), ... market leader in medication reconciliation solutions, has entered,into ... the largest,locally owned not-for-profit hospitals in the nation ... as a teaching facility for The,University of Alabama ...
... the Internet, calls for action from ICANN, US-based domain ... ... 21 LegitScript.com, an,online pharmacy verification service, and KnujOn.com, an Internet ... engaged in the illicit sale of anabolic steroids., Steroid abuse ...
... future alternative to bypass surgery, researchers say , , FRIDAY, ... grown in mice the kind of functioning heart blood ... One ultimate goal is to replace some heart surgery ... in the body, providing a system of blood vessels ...
... more likely to be iron-deficient, study finds , , FRIDAY, ... breast-fed for the first six months of life are ... likely to be deficient in iron, and therefore at ... at 154 mothers and their babies in Guadalajara, Mexico. ...
... July 18 (HealthDay News) -- Correcting lazy eye in adults ... been able to do that -- at least partially and ... Someone with lazy eye -- ophthalmologists call it amblyopia -- ... other. Early treatment often has a child wearing a patch ...
Cached Medicine News:Health News:Daniel E. Crookshank Joins Mylan as Vice President - Investor Relations 2Health News:Huntsville Hospital Signs With Health Care Systems, Inc. for Automated Medication Reconciliation Services 2Health News:Kids at Risk: Report Identifies 150 Websites Selling Anabolic Steroids 2Health News:Heart Blood Vessels Grown in the Lab 2Health News:Breast-Fed Babies Have Fewer GI Infections 2Health News:Magnetic Pulses to Brain Improve Lazy Eye in Adults 2Health News:Magnetic Pulses to Brain Improve Lazy Eye in Adults 3
(Date:1/14/2014)... 2014 InformEx, North America,s leading ... will hold the 30 th edition of its annual ... Center from January 21-24. (Logo: http://photos.prnewswire.com/prnh/20131028/NY05330LOGO-a ) ... fine chemical and specialty chemical companies will take part in ...
(Date:1/14/2014)... 2014 /PRNewswire-iReach/ -- Acumed,s new SLIC Screw System - ... instrumentation to place and insert the screw accurately - ... (e.g. ligament) repair or reconstruction as it holds the ... (Photo: http://photos.prnewswire.com/prnh/20140114/MN45636 ) The SLIC ...
(Date:1/14/2014)... CLEVELAND , Jan. 14, 2014 NineSigma ... will hold its Innovation Leadership Summit , May ... in Cleveland Ohio . ... innovators and organizations committed to breakthrough achievements through open ...
Breaking Medicine Technology:Media Advisory: InformEx 2014 Events & Speaker Lineup for 30th Edition Conference in Miami Beach 2Acumed introduces the Scapho-Lunate Inter Carpal (SLIC) Screw System 2Acumed introduces the Scapho-Lunate Inter Carpal (SLIC) Screw System 3Expect the Unexpected from Leading Global Innovators at NineSigma Leadership Summit, Sharing Winning Strategies to Advance Innovation 2Expect the Unexpected from Leading Global Innovators at NineSigma Leadership Summit, Sharing Winning Strategies to Advance Innovation 3Expect the Unexpected from Leading Global Innovators at NineSigma Leadership Summit, Sharing Winning Strategies to Advance Innovation 4
... Wash., Jan. 24, 2011 Cardiac Science Corporation ... AED ) and diagnostic cardiac monitoring devices, ... Army,s Research, Development, and Engineering Command for the ... indicates the Powerheart AED G3 Pro complies with U.S. ...
... 2011 Medco Health Solutions, Inc. (NYSE: ... 2010 financial results in a press release before the ... (Logo: http://photos.prnewswire.com/prnh/20100609/MEDCOLOGO) Following the release, management ... results, outlook and related matters at 8:30 a.m. ET. ...
Cached Medicine Technology:Cardiac Science Awarded US Military Certification 2Cardiac Science Awarded US Military Certification 3Cardiac Science Awarded US Military Certification 4Medco Announces Date for Release of Fourth-Quarter and Full-Year 2010 Financial Results 2
The Precedent establishes a new generation of revision hip stems....
Calcar replacement stems provide options for revision and trochanteric fractures. Revision hip surgery and trauma often require prosthetic designs that replace proximal medial calcar bone loss....
...
...
Medicine Products: