Navigation Links
DNA May Explain Why Women Have More Rheumatoid Arthritis
Date:11/26/2012

MONDAY, Nov. 26 (HealthDay News) -- Genes specific to the X chromosome are among newly identified genes linked to rheumatoid arthritis and could help explain why women are more likely than men to develop the disease, researchers say.

Women have two X chromosomes while men have an X and a Y chromosome.

The X-chromosome-specific genes were among 14 newly identified genes in both women and men that can lead to rheumatoid arthritis, adding to the 32 genes previously pinpointed by the researchers at the Arthritis Research U.K. Epidemiology Unit at the University of Manchester and their colleagues.

It is believed that these 46 genes account for the vast majority of genes associated with rheumatoid arthritis. The research could lead to new treatments for the disease, according to the study published online recently in the journal Nature Genetics.

"This groundbreaking study brought together scientists from around the world and involved the use of DNA samples from more than 27,000 patients with rheumatoid arthritis and healthy controls," study lead author Jane Worthington, professor of chronic disease genetics at the University of Manchester, said in a university news release. "As a result of our findings, we now know that genetic variations at over 45 regions of the genome determine susceptibility to this form of arthritis."

Rheumatoid arthritis is different from osteoarthritis, the arthritis associated with aging and wear and tear. It frequently starts between the ages of 25 and 55, and causes inflammation in the joints, resulting in swelling, stiffness, pain and reduced joint function.

Lifestyle and environmental factors such as smoking, diet, pregnancy and infection are believed to play a role in rheumatoid arthritis, but a person's genes also influence their risk for the disease. The condition affects about 1 percent of the world's population.

"This work will have a great impact on the clinical
'/>"/>

Copyright©2012 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. Queens research gives fresh hope to couples with unexplained infertility
2. Rise in Pregnancy-Associated Cancers Not Fully Explained by Older Age
3. Immune system protein could explain pancreatitis
4. Why are elderly duped? UI researchers explain why
5. Scientists discover new clues explaining tendon injury
6. Discovery explains how cellular pathways converge to regulate food intake and body weight
7. US Drug Watchdog Now Offers to Help All Woman Who Used Fosamax For Osteoporosis and Then Had an Unexplained a Femur Break Get to the Best Attorneys
8. Shorter Arms May Explain Why Women Need Glasses Sooner Than Men
9. New mouse model helps explain gene discovery in congenital heart disease
10. US Drug Watchdog Now Offers To Help Women Who Used TheOsteoporosis Drug Called Fosamax And Then Had A Unexplainable Femur Fracture Get To The Best Attorneys Or Law Firms
11. Wake Forest Baptist research provides clue to unexplained excited delirium deaths
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
DNA May Explain Why Women Have More Rheumatoid Arthritis
(Date:8/1/2014)... August 01, 2014 As AndroGel lawsuits ... country, Ronald E. Johnson, Jr. has been appointed as ... and other testosterone medications. Since the Fall of 2013, ... have worked diligently to investigate and prosecute the claims ... and blood clots as a result of taking testosterone. ...
(Date:8/1/2014)... a cancer diagnosis may improve health outcomes for Asian-American ... a researcher at the University of Houston (UH). ... is the writing instruction. Otherwise, writing is just like ... can be therapeutic, but oftentimes we don,t get the ... said Qian Lu, assistant professor and director of the ...
(Date:8/1/2014)... August 01, 2014 Growing prevalence ... and healthcare reforms are boosting healthcare market growth, ... through discounts and increasing generic consumption is a ... 76.7 million in 2013, having grown at a ... 2008. The implementation of the Health Transformation Program ...
(Date:8/1/2014)... Hot off the presses after the announcement of ... World’s Best Awards by Travel + Leisure , The ... Relaxation Day (technically August 15). , The Lodge at ... help guests celebrate relaxation throughout the month of August. ... wellness to carve out time to relax and unwind. ...
(Date:8/1/2014)... 2014 The "Antimicrobial Coatings Market ... Zinc Oxide, Titanium Dioxide, and Zinc Omadine), Application ... Food & Beverages, Textiles, and others), & Geography ... Trends and Forecasts to 2018" analyzes the Antimicrobial ... and trends in the diverse geographical regions. , ...
Breaking Medicine News(10 mins):Health News:Ron Johnson Named Co-Lead Counsel in Lawsuits for Men Injured by AndroGel and Testosterone 2Health News:Expressive writing may help breast cancer survivors 2Health News:Expressive writing may help breast cancer survivors 3Health News:Turkey Pharmaceutical and Medical Device Market Worth $21.5B & $3.3B by 2020 Respectively, Says a Report Available at MarketOptimizer.org 2Health News:Turkey Pharmaceutical and Medical Device Market Worth $21.5B & $3.3B by 2020 Respectively, Says a Report Available at MarketOptimizer.org 3Health News:Turkey Pharmaceutical and Medical Device Market Worth $21.5B & $3.3B by 2020 Respectively, Says a Report Available at MarketOptimizer.org 4Health News:The Lodge at Woodloch Kicks Off National Relaxation Day with a Month Long Celebration 2Health News:The Lodge at Woodloch Kicks Off National Relaxation Day with a Month Long Celebration 3Health News:The Lodge at Woodloch Kicks Off National Relaxation Day with a Month Long Celebration 4Health News:Antimicrobial Coatings Market Projected to Reach $2.9 Billion by 2018 – Report by MarketsandMarkets 2Health News:Antimicrobial Coatings Market Projected to Reach $2.9 Billion by 2018 – Report by MarketsandMarkets 3Health News:Antimicrobial Coatings Market Projected to Reach $2.9 Billion by 2018 – Report by MarketsandMarkets 4
... General Hospital,became the first hospital in Palm Beach County ... Electronic Birth Registry (EBR) system,launched on August 8, Glades ... reducing the costs and processing time. Now,the staff at ... the,report, and get the required electronic signatures -- all ...
... ATSI ), manufacturer and marketer of state-of-the-art ... will present at the,2007 Thomas Weisel Partners Healthcare ... Company,s presentation is scheduled for Wednesday, September,5, 2007 ... and CEO of ATS,Medical, will present a review ...
... Matrixx Initiatives, Inc.,(Nasdaq: MTXX ), an over-the-counter healthcare ... "Better Ways to Get,Better(R)," will be presenting on September ... Conference. The Company will be presenting at 11:30 ... http://www.matrixxinc.com . Interested parties,should login 15 minutes prior ...
... in,health-related research grew by a modest 4.2% from 2005 ... health costs, according,to a report released today by Research!America. ... Science. The nation spent approximately $116 billion last ... and prevent disease and disability. This,represents a decrease relative ...
... in Italian study , , THURSDAY, Aug. 30 (HealthDay News) -- ... of dying in the next year compared to those who ... number of other studies have shown the benefits of using ... instance, the Italian study comes on the heels of a ...
... A drug that shuts down a critical cell-signaling pathway ... brain cancer successfully kills cancer stem cells thought to ... radiation therapy, a Johns Hopkins study shows. , In ... scientists blocked the signaling system, known as Hedgehog, with ...
Cached Medicine News:Health News:Glades General Hospital First in Palm Beach County to Provide On-Site Electronic Birth Registration 2Health News:Glades General Hospital First in Palm Beach County to Provide On-Site Electronic Birth Registration 3Health News:ATS Medical to Present at the 2007 Thomas Weisel Partners Healthcare Conference 2Health News:Matrixx Initiatives, Inc. to Present at the Roth Capital Partners 2007 New York Conference 2Health News:U.S. Research Funding Continues to Flatten as U.S. Health Costs Climb - in August 31 Science 2Health News:Stopping Statins After Stroke Doubles Death Risk 2Health News:Stopping Statins After Stroke Doubles Death Risk 3Health News:Experimental anti-cancer drug made from corn lillies kills brain tumor stem cells 2Health News:Experimental anti-cancer drug made from corn lillies kills brain tumor stem cells 3
(Date:8/1/2014)... Research and Markets  has announced ... Testing Markets (Lab-Based, Professional POC, Home, Employment, Criminal ... http://photos.prnewswire.com/prnh/20130307/600769 ... in IVD testing with competitive participation by top ... criminal justice personnel, and sports use drug tests ...
(Date:8/1/2014)... 1, 2014 Aspire Technology Partners (Aspire) announced today ... from Cisco. This designation recognizes Aspire for delivering outstanding customer ... America . "Achieving exceptional results for our ... Harris , President and CEO of Aspire. "We are pleased ... Gold Star award and are proud to be part of ...
(Date:8/1/2014)... Medical, Inc. (Nasdaq: NXTM ), a leading manufacturer ... Burbank , Chief Executive Officer, and Mathew Towse , ... Annual Canaccord Genuity Growth Conference being held at the InterContinental ... 13 th at 4:30 p.m. ET.  A webcast of ... About NxStage Medical NxStage Medical, ...
Breaking Medicine Technology:Drugs of Abuse Testing Markets (Lab-Based, Professional POC, Home, Employment, Criminal Justice Markets) 2Aspire Technology Partners Recognized By Cisco For Excellence In Customer Satisfaction 2NxStage to Present at the 34th Annual Canaccord Genuity Growth Conference 2
... Mass. , Feb. 4 Recognizing that corporate ... they contain, Northern Light ( www.northernlight.com ) today announced that ... excess of $2 billion can be searched, analyzed ... been steadily increasing the number of market research sources integrated ...
... N.C. , Feb. 4 Gorbec Pharmaceutical ... prescription pharmaceutical products, is opening a GMP-compliant analytical laboratory ... expand Gorbec,s current services for analytical method development and ... its U.S. customer base as well as develop a ...
Cached Medicine Technology:Northern Light Surpasses $2 Billion Worth of Research Content Integrated Into SinglePoint Strategic Research Portals 2Northern Light Surpasses $2 Billion Worth of Research Content Integrated Into SinglePoint Strategic Research Portals 3Gorbec Pharmaceutical Services, Inc. Announces the Launch of Its GMP Analytical Laboratory in China 2
ELISA kit for the quantitative determination of autoantibodies to thyroid peroxidase (TPO) in serum...
ELISA kit for the quantitative determination of autoantibodies to thyroglobulin in serum....
... the most potent, naturally secreted estrogen and ... ovary [1]. In the ovary, estradiol is ... a less potent estrogen derived from androstenedione. ... body tissues. In men, small amounts of ...
... troponin I (cTnI) has been useful in ... Emergency Departments (ED) with chest pain. 18-20 ... when blood levels of sensitive and specific ... isoenzyme of creatine kinase (CK-MB), and myoglobin, ...
Medicine Products: