Navigation Links
DNA Fingerprints Predict Brain Disorders
Date:1/18/2008

Researchers found certain variations may indicate higher risk of ALS, Parkinson's

FRIDAY, Jan. 18 (HealthDay News) -- Predicting brain disorders such as Parkinson's disease and amyotrophic lateral sclerosis (ALS) may be possible by identifying certain DNA fingerprints, a recent Mayo Clinic study suggests.

The researchers analyzed the genetic data of people with ALS (also known as Lou Gehrig's disease) and Parkinson's, and those without neurological disorders. They pinpointed several gene variations that predicted who was at higher risk for developing the disorders, according to the study published online in PLoS One.

The variations were found by studying the axon guidance pathway, a complex collection of chemical signals that wire the brain during fetal development, and maintain and repair brain circuits throughout a person's life.

Researchers found many variations within pathway genes common to ALS and Parkinson's. However, they also identified several that collectively indicate people at high risk (2,000 times greater than the general population) for ALS. And they pinpointed several gene variations that collectively predicted people at high risk (nearly 400 times greater than the general population) for Parkinson's disease.

"In persons at high risk, we may be able to prevent the diseases or slow or halt their progression by developing drugs that target the same disease pathways. For ALS and Parkinson's disease, our study is a major step in these directions," principal investigator and Mayo Clinic neurologist Dr. Demetrius Maraganore said in a prepared statement.

ALS is a progressive neurodegenerative disease that leads to loss of muscle control and use, and eventually death. As many as 30,000 Americans have the disease at any given time, according to the ALS Association. Parkinson's disease, a brain disorder that affects 1.5 million Americans, causes tremors, slowness of movement, and body stiffness, according to the National Parkinson Foundation. No cure exists for either disease.

More information

The Muscular Dystrophy Association has more about ALS.



-- Robert Preidt



SOURCE: Mayo Clinic, news release, Jan. 15, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. U.S. Preventive Medicine(R) Predicts Robust Growth Ahead
2. UQ research predicts type 2 diabetes explosion
3. Simple test accurately predicts risk of serious jaundice in newborns
4. 5 Factors Help Predict Psychosis in Children
5. Private Equitys Top Execs to Share Advice, Candid Predictions at 2008 Outlook Conference
6. American Council On Exercise (ACE) 2008 Fitness Trend Predictions
7. Area Around Breast Tumor May Predict Cancers Spread
8. Six Positive Predictions for 2008, from SuperLife World Service
9. Bone Density Tests Do Predict Womens Fracture Risk
10. MammaPrint(R) Breast Cancer Test Shown To Be Powerful Tool for Prognosis Prediction in Postmenopausal Breast Cancer Patients
11. Predicting post-traumatic stress disorders in deployed veterans
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
DNA Fingerprints Predict Brain Disorders
(Date:5/27/2016)... ... May 27, 2016 , ... An influential resource amongst nurses and professionals ... shed lights on the variety of topics detailing why we appreciate nurses in so ... this career has gone from being in a major recession to one of the ...
(Date:5/27/2016)... ... May 27, 2016 , ... An educational campaign aimed ... human-interest stories, courtesy of awareness-driven celebrities and thought leaders. It also provides insight ... and industry leaders such as Bioness. , As patients feel increasingly concerned ...
(Date:5/27/2016)... ... May 27, 2016 , ... Aimed at nurses and ... interest stories, courtesy of leaders in the nursing and health care industry. It ... leading advocates and associations—namely Jones & Bartlett Learning. , Jones & Bartlett Learning ...
(Date:5/27/2016)... , ... May 27, 2016 , ... ... name in the pharmaceutical, medical and food industries. Aside from its GMP accreditation, ... (SIC), providing proof of successfully certified products, services and staff. , Validation Center ...
(Date:5/26/2016)... ... May 26, 2016 , ... W.S. Badger Co. Inc ., ... with a 2016 When Work Works Award for its use of effective workplace strategies ... When Work Works project administered by the Families and Work Institute (FWI) and the ...
Breaking Medicine News(10 mins):
(Date:5/27/2016)... 2016 According to the 2016 ... driving ambulatory blood pressure monitoring system market growth. With ... ability to respond to different pressure rates, leading to ... to various cardiovascular disorders such as heart failure, stroke, ... are growing in prevalence each year. WHO estimates that ...
(Date:5/27/2016)... May 27, 2016 The healthcare ... health insurance companies all falling under its umbrella.  A ... While not often talked about, these healthcare companies are ... States is by far the largest consumer ... Isotope Corp. (OTC: ADMD), Nutranomics Inc. (OTC: NNRX), KollagenX ...
(Date:5/26/2016)... NASHVILLE, Tenn. , May 26, 2016 ... provider of software and analytics, network solutions ... healthcare, today announced it entered into a ... leading provider of outpatient software solutions and ... surgery centers, specialty hospitals and rehabilitation clinics ...
Breaking Medicine Technology: