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DNA Direct and Iverson Genetics Announce Partnership to Provide Personalized Patient Reports for Warfarin Dosing Test Results
Date:7/10/2008

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The web-enabled reports will be personalized to the patient's actual test results, explaining the implications for both general drug response and warfarin dosing. The reports will also explain how genes affect drug response, what factors impact warfarin dosing and what next steps may be most appropriate. Patients will be able to download a copy of their lab report, as well as a clinical summary letter to be shared with their physicians. Patients may return to their report at a later date to determine how metabolism status may impact drug response for certain additional medications.

In August 2007, the U.S. Food and Drug Administration (FDA) updated labeling on warfarin, the oral anticoagulant most frequently used to control and prevent thromboembolic disorders, indicating that people with variations of the genes CYP2C9 and VKORC1 may respond differently to the drug(1). FDA black box warnings flag physicians that patients over 65 years of age carry a higher risk for bleeding and require special vigilance. This information, combined with several clinical studies, has encouraged physicians to recommend genetic testing to better support determining a patient's optimal dose. Too high of a dose contributes to life-threatening bleeding, and too low a dose places the patient at risk of life-threatening blood clots.

About Iverson Genetic Diagnostics, Inc.

Iverson Genetic Diagnostics is a privately held company headquartered at Institute for Systems Biology. Iverson provides genetic testing services nationwide with service representatives calling on physicians and clinics in Washington, Oregon, Texas, Idaho, Montana and Alaska. With a CLIA laboratory and MTS (Medical Testing Site) certification for high complexity molecular genetic testing, Iverson has the capacity for processing 17,500 tests per month. Additional information about Iverson Genetic Diagnostics, Inc. is available at

SOURCE DNA Direct, Inc.; Iverson Genetic Diagnostics, Inc.
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