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DNA Direct Announces Availability of ColoSure(TM) Colorectal Cancer Screening Test
Date:10/1/2008

Gastroenterology shows that detecting methylated vimentin DNA in feces provided both high sensitivity (77%) and high specificity (83%) for detecting early-stage, curable colon cancers.

"These data support the use of the ColoSure assay as a non-invasive screening option," said Trish Brown, M.S., CGC, vice president of clinical affairs of DNA Direct. "This assay is among the most sensitive, non-invasive colorectal cancer screening tools available to supplement screening between recommended colonoscopy intervals."

DNA Direct's personalized, web-enabled report for recipients of the ColoSure test includes an overview of test results, a lab report and letter to bring to their physician, and recommended next steps. Reports also reinforce awareness of the signs and symptoms of colorectal cancer, and include an option to schedule a reminder for the patient's next screening. Finally, the report includes a section on how ColoSure works, ways to change contributing lifestyle factors, a list of resources for patients and important facts about colorectal cancer.

About ColoSure(TM)

The ColoSure(TM) assay assesses the presence of active colorectal cancer in average-risk individuals. The assay is performed, after a simple collection process, on a complete bowel movement, and examines DNA in exfoliated colon cells for a change that can indicate the presence of cancer. The ColoSure assay can be used as a part of a comprehensive, ongoing colorectal cancer-screening program, and is complementary to both traditional and virtual colonoscopies; current U.S. guidelines emphasize routine screening beginning at age 50. ColoSure has a sensitivity range (meaning that it detects the presence of cancer) of 72-77 percent, and a specificity range (meaning that it detects the absence of cancer) of 83-94 percent.

About DNA Direct

DNA Direct is a San Francisco-based, privately held company that provides convenient, clinically valid personal genetic information
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SOURCE DNA Direct
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