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DNA Direct Announces Availability of ColoSure(TM) Colorectal Cancer Screening Test
Date:10/1/2008

- Publication in American Journal of Gastroenterology Supports Non-Invasive

Screening Option for Colorectal Cancer -

SAN FRANCISCO, Oct. 1 /PRNewswire/ -- DNA Direct, Inc. today announced that the company will offer ColoSure(TM), a state of the art, safe, simple, and convenient test to screen for colon cancer -- the second leading cause of cancer-related deaths in the United States. ColoSure tests a single stool sample for a DNA marker associated with colorectal cancer, and may be ordered through DNA Direct's website at http://www.dnadirect.com.

"This is an example of how genetic testing can impact healthcare decisions today, and we're excited to be offering a screening option that allows for early and potentially life-saving detection of colon cancer," said Ryan Phelan, founder and CEO of DNA Direct. "The ColoSure assay allows those who might be anxious or fearful about invasive screening methods like colonoscopy to take steps to detect colorectal cancer in its earliest, most curable stages."

At least 60 percent of Americans age 50 and older have never been screened for colorectal cancer, even though the American Cancer Society recommends a lifelong screening program for those aged 50 or older, including a colonoscopy every ten years. Each year, nearly 150,000 new cases are diagnosed, and up to 50,000 people die of colorectal cancer. If caught early, the survival rate is close to 95 percent -- but 50 percent of patients with colorectal cancer are diagnosed with advanced disease, which is less likely to be surgically curable.

ColoSure is the first clinical test available that looks for a DNA change in the vimentin gene, shown to be important to immunity and other important cell processes in the body. If the vimentin gene is hyper-methylated, or "turned off," this could indicate colon cancer. A study published in the September 2008 issue of the American Journal of
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SOURCE DNA Direct
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