Navigation Links
DNA-Based HPV Tests More Accurate Than Pap Smears
Date:3/25/2008

Findings show they detect more precancerous cervical lesions

TUESDAY, March 25 (HealthDay News) -- A new study confirms previous findings that human papillomavirus (HPV) DNA-based tests are more accurate than Pap smears in detecting precancerous lesions.

It was already known that the HPV test uncovered more infections and precancerous lesions than Pap smears (cytology), but it wasn't clear whether HPV tests would lead to the treatment of patients whose immune systems would fight off infections -- meaning that these women didn't require treatment, anyway.

In this study of almost 50,000 women, Italian researchers found that the HPV test identified almost twice as many premalignant lesions compared to Pap smears. Among women ages 35 to 60, the HPV test was more likely to detect cervical lesions. In women ages 25 to 34, the HPV test seemed to identify more infections that eventually resolved themselves.

Based on their findings, the researchers said it may be best for younger women with a positive HPV test to be retested in 12 months, rather than being immediately referred for a more intensive examination called colposcopy.

"It seems clear that an HPV DNA-based approach to primary screening is a very attractive option that should be actively developed and evaluated," wrote Dr. Guglielmo Ronco, from CPO Piemonte, in Torino, Italy, and colleagues.

The findings of this study, which were published in the Journal of the National Cancer Institute, reinforced similar findings in a study published in 2006 by Ronco and team.

That earlier study of 33,364 women, ages 35 to 60, found that HPV testing combined with liquid-based Pap testing detected 47 percent more precancerous lesions than conventional Pap smears. However, the combination testing increased the chance of false positives by 60 percent.

HPV accounts for almost all cases of cervical cancer.

More information

The U.S. National Women's Health Information Center has more about cervical cancer.



-- Robert Preidt



SOURCE: Journal of the National Cancer Institute, news release, March 25, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Experts propose cholesterol tests at 15 months of age
2. Fecal Blood Tests Effective at Spotting Colon Cancer
3. Drug Industry Seeks Tests to Spot Side Effect Risks
4. Noninvasive tests for cirrhosis may help to avoid liver biopsy
5. K-State Veterinary Lab Routinely Tests For Bluetongue Virus; Lab Director Says Strains Found in Kansas, U.S. Usually Less-Virulent
6. Gene Tests Match Up Lung Tumors, Best Treatment
7. Mayo Clinic tests novel vaccine for aggressive brain tumors
8. Cepheid and Broadlane Sign Group Purchasing Contract for GeneXpert(R) Systems and Xpert(TM) Molecular Diagnostic Tests, Including Xpert MRSA
9. Bone Density Tests Do Predict Womens Fracture Risk
10. Mini stress tests could help condition heart to survive major attack
11. Lab on a chip developed at University of Alberta for cheap, portable medical tests
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... ... ... First Choice Emergency Room , the largest network of independent freestanding ... of its new Mesquite-Samuell Farm facility. , “We are pleased to announce Dr. ... James M. Muzzarelli, Executive Medical Director of First Choice Emergency Room. , Dr. ...
(Date:6/25/2016)... ... June 25, 2016 , ... ... recover from injury. Recently, he has implemented orthobiologic procedures as a method for ... is one of the first doctors to perform the treatment. Orthobiologics are substances ...
(Date:6/25/2016)... ... June 25, 2016 , ... Conventional wisdom preaches the benefits ... terms of the latter, setting the bar too high can result in disappointment, perhaps ... slow progress toward their goal. , Research from PsychTests.com reveals that ...
(Date:6/24/2016)... ... June 24, 2016 , ... Those who have experienced traumatic ... many turn to unhealthy avenues, such as drug or alcohol abuse, as a coping ... released tools for healthy coping following a traumatic event. , Trauma sufferers tend to ...
(Date:6/24/2016)... ... June 24, 2016 , ... Marcy was in a crisis. Her son James, eight, was out ... family verbally and physically. , “When something upset him, he couldn’t control his emotions,” remembers ... would throw rocks at my other children and say he was going to kill them. ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... June 24, 2016 Research and Markets ... for Companion Diagnostic Tests" report to their offering. ... Companion Diagnostics The World Market for Companion ... medicine diagnostics. Market analysis in the report includes the following: ... (In Vitro Diagnostic Kits) by Region (N. America, EU, ROW), ...
(Date:6/23/2016)... -- MedSource announced today that it has selected Datatrial,s ... choice.  This latest decision demonstrates MedSource,s commitment to ... by offering a state-of-the-art electronic data capture (EDC) ... the EDC platform of choice in exchange for ... long been a preferred EDC platform by our ...
(Date:6/23/2016)... 2016 Roche (SIX: RO, ROG; OTCQX: RHHBY) ... Elecsys BRAHMS PCT (procalcitonin) assay as a dedicated testing ... With this clearance, Roche is the first IVD company ... for sepsis risk assessment and management. PCT ... PCT levels in blood can aid clinicians in assessing ...
Breaking Medicine Technology: