Navigation Links
DNA-Based HPV Tests More Accurate Than Pap Smears

Findings show they detect more precancerous cervical lesions

TUESDAY, March 25 (HealthDay News) -- A new study confirms previous findings that human papillomavirus (HPV) DNA-based tests are more accurate than Pap smears in detecting precancerous lesions.

It was already known that the HPV test uncovered more infections and precancerous lesions than Pap smears (cytology), but it wasn't clear whether HPV tests would lead to the treatment of patients whose immune systems would fight off infections -- meaning that these women didn't require treatment, anyway.

In this study of almost 50,000 women, Italian researchers found that the HPV test identified almost twice as many premalignant lesions compared to Pap smears. Among women ages 35 to 60, the HPV test was more likely to detect cervical lesions. In women ages 25 to 34, the HPV test seemed to identify more infections that eventually resolved themselves.

Based on their findings, the researchers said it may be best for younger women with a positive HPV test to be retested in 12 months, rather than being immediately referred for a more intensive examination called colposcopy.

"It seems clear that an HPV DNA-based approach to primary screening is a very attractive option that should be actively developed and evaluated," wrote Dr. Guglielmo Ronco, from CPO Piemonte, in Torino, Italy, and colleagues.

The findings of this study, which were published in the Journal of the National Cancer Institute, reinforced similar findings in a study published in 2006 by Ronco and team.

That earlier study of 33,364 women, ages 35 to 60, found that HPV testing combined with liquid-based Pap testing detected 47 percent more precancerous lesions than conventional Pap smears. However, the combination testing increased the chance of false positives by 60 percent.

HPV accounts for almost all cases of cervical cancer.

More information

The U.S. National Women's Health Information Center has more about cervical cancer.

-- Robert Preidt

SOURCE: Journal of the National Cancer Institute, news release, March 25, 2008

Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Experts propose cholesterol tests at 15 months of age
2. Fecal Blood Tests Effective at Spotting Colon Cancer
3. Drug Industry Seeks Tests to Spot Side Effect Risks
4. Noninvasive tests for cirrhosis may help to avoid liver biopsy
5. K-State Veterinary Lab Routinely Tests For Bluetongue Virus; Lab Director Says Strains Found in Kansas, U.S. Usually Less-Virulent
6. Gene Tests Match Up Lung Tumors, Best Treatment
7. Mayo Clinic tests novel vaccine for aggressive brain tumors
8. Cepheid and Broadlane Sign Group Purchasing Contract for GeneXpert(R) Systems and Xpert(TM) Molecular Diagnostic Tests, Including Xpert MRSA
9. Bone Density Tests Do Predict Womens Fracture Risk
10. Mini stress tests could help condition heart to survive major attack
11. Lab on a chip developed at University of Alberta for cheap, portable medical tests
Post Your Comments:
(Date:11/27/2015)... PITTSBURGH, PA (PRWEB) , ... November 27, 2015 ... ... of how filthy the toilets were," said an inventor from Hillside, N.J. "Many ... this improved seat cover so that individuals will always be protected from germs." ...
(Date:11/27/2015)... ... November 27, 2015 , ... Consistent with the ... 2016 Building Better Radiology Marketing Programs meeting will showcase some of the ... 2016, at Caesars Palace in Las Vegas with a pre-conference session on a ...
(Date:11/27/2015)... ... November 27, 2015 , ... CBD College is proud ... Education Programs (CAAHEP) awarded accreditation to its Diagnostic Medical Sonography program. CBD College is ... only one of twelve colleges and universities in the state of California make the ...
(Date:11/26/2015)... ... November 26, 2015 , ... Patients at Serenity Point ... come together on Thanksgiving Day to share the things that they are most ... Serenity Point YouTube channel, patients displayed what they wrote on index cards, describing ...
(Date:11/26/2015)... ... November 26, 2015 , ... Jobs in hospital medical laboratories and in ... by healthcare staffing agency Aureus Medical Group . These fields, as ... among those searching for healthcare jobs through the company’s website, , ...
Breaking Medicine News(10 mins):
(Date:11/26/2015)... -- Research and Markets ( ) has ... Horizons and Growth Strategies in the Italian Therapeutic ... Forecasts, Competitive Intelligence, Emerging Opportunities" report to ... --> This new 247-page report provides ... monitoring market, including emerging tests, technologies, instrumentation, sales ...
(Date:11/25/2015)... global healthcare industry is expected to grow at a rate ... has the highest projected growth at 12.7%, and ... is second with growth projected at 11.5%. ... 2013-2014, total government funded healthcare was nearly 68%. Federal government ... 2013-2014. In real terms, out of pocket expenditure increased by ...
(Date:11/25/2015)... , Nov. 25, 2015 AAIPharma ... planned investment of at least $15.8  Million to ... Wilmington, NC . The expansion will ... to meet the growing demands of the pharmaceutical ... site expansion will provide up to 40,000 ...
Breaking Medicine Technology: