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DARPA selects Lawrence Livermore to develop world's first neural device to restore memory
Date:7/8/2014

evelop cutting-edge medical devices that will change the health care landscape."

LLNL will develop a state-of-the-art miniature, wireless and chronically implantable neural device that will incorporate both single neuron and local field potential recordings into a closed-loop system to implant into TBI patients' brains. The device--implanted into the entorhinal cortex and hippocampus--will allow for stimulation and recording from 64 channels located on a pair of high-density electrode arrays. The entorhinal cortex and hippocampus are regions of the brain associated with memory.

The arrays will connect to an implantable electronics package capable of wireless data and power telemetry. An external electronic system worn around the ear will store digital information associated with memory storage and retrieval and provide power telemetry to the implantable package using a custom RF-coil system.

Designed to last throughout the duration of treatment, the device's electrodes will be integrated with electronics using advanced LLNL integration and 3D packaging technologies. The microelectrodes that are the heart of this device are embedded in a biocompatible, flexible polymer.

Using the Center for Bioengineering's capabilities, Pannu and his team of engineers (neurotech.llnl.gov/people) have achieved 25 patents and many publications during the last decade. The team's goal is to build the new prototype device for clinical testing by 2017.

Lawrence Livermore's collaborators, UCLA and Medtronic, will focus on conducting clinical trials and fabricating parts and components, respectively.

"The RAM program poses a formidable challenge reaching across multiple disciplines from basic brain research to medicine, computing and engineering," Itzhak Fried, lead investigator for the UCLA on this project and a professor of neurosurgery and psychiatry and biobehavioral sciences at the David Geffen School of Medicine at UCLA and the
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Contact: Ken Ma
ma28@llnl.gov
925-423-7602
DOE/Lawrence Livermore National Laboratory
Source:Eurekalert  

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DARPA selects Lawrence Livermore to develop world's first neural device to restore memory
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