Navigation Links
DAI provides potential imaging biomarker to indicate brain tumor response to RT
Date:2/8/2013

Orlando, Fla., February 8, 2013 Diffusion abnormality index (DAI) shows promise as an imaging biomarker to measure brain tumor response to radiation therapy, according to research being presented at the 2013 Cancer Imaging and Radiation Therapy Symposium. This Symposium is sponsored by the American Society for Radiation Oncology (ASTRO) and the Radiological Society of North America (RSNA).

The study included 20 patients who had brain metastases and were treated with whole brain radiotherapy. The total of 45 lesions among the patients was further categorized as 16 responsive, 18 stable and 11 progressive lesions. Diffusion measurements were taken prior to radiation treatment, two weeks after the start of treatment and one month after treatment completion. For each patient, a normal tissue apparent diffusion coefficient (ADC) histogram was used to divide the tumor ADC histogram into three regions: low (high cellularity), normal and high (edema and necrosis) diffusion. Analyzing the complex behavior in ADC of brain metastases from pre-radiation therapy to two weeks after starting treatment, investigators developed a new diffusion index, the DAI, which included both low and high ADC contributions, for prediction of post-treatment tumor response.

Sensitivity and specificity of the change in DAI from pre- to the end of therapy were evaluated and compared with the changes in gross tumor volume from pre-treatment to the end of therapy. The changes were valuable in predicting non-responsive lesions post-treatment. Early prediction of brain tumor response to radiation therapy is vital in providing the most appropriate radiation doses to each lesion.

"While this review included a small number of patients, the data demonstrate that DAI may be a good biomarker to predict brain tumor response," said lead study author Reza Farjam, a PhD candidate in biomedical engineering focused on cancer functional imaging at the University of Michigan in Ann
'/>"/>

Contact: Michelle Kirkwood
press@astro.org
703-286-1600
American Society for Radiation Oncology
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Adding drug to standard chemotherapy provides no survival benefit for older lung cancer patients
2. Study of half siblings provides genetic clues to autism
3. Partnership provides inclusive workout
4. 16th-century Korean mummy provides clue to hepatitis B virus genetic code
5. InsuranceCalculator.net Now Provides Competitive Car Insurance Quotes To Missouri Drivers
6. SEOMiracle.com Provides SEO Services with PayPal Verified Option
7. InsuranceCalculator.net Now Provides Competitive Car Insurance Quotes To Maryland Drivers
8. Wake Forest Baptist research provides clue to unexplained excited delirium deaths
9. Autism Speaks provides strategies to help a child with autism shows difficult behaviors
10. InsuranceCalculator.net Now Provides Competitive Car Insurance Quotes To South Carolina Drivers
11. InsuranceCalculator.net Now Provides Competitive Car Insurance Quotes To Louisiana Drivers
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/10/2014)... New York (PRWEB) July 10, 2014 ... dedicated to protecting the rights of victims injured ... has brought a lawsuit over allegations that the ... body by a power morcellator used during a ... been filed against Richard Wolf Medical Instruments Corporation ...
(Date:7/10/2014)... July 10, 2014 (HealthDay News) -- Most professional football ... return to the game, a new study finds. ... but their rate of return after surgery to fix ... The new study included 60 players who had ... this procedure successfully returned to play, defined as playing ...
(Date:7/10/2014)... Thompson HealthDay Reporter THURSDAY, ... wars that break out regularly between outspoken celebrities or loudmouth ... own relationship, a new study suggests. High amounts of ... if the couple is in a long-term relationship, according to ... In turn, that friction can lead to cheating and breakups, ...
(Date:7/10/2014)... device developed at the Massachusetts General Hospital (MGH) Center ... can be cultured to establish cell lines for genetic ... issue of Science , an MGH research team ... genetic mutation over time and changing susceptibility to therapeutic ... the blood that represent those present in metastatic deposits, ...
(Date:7/10/2014)... to bump up their grade point averages during college, ... a library or study hall, but in a gym. ... who were members of the recreational sports and fitness ... years had higher GPAs than those who weren,t. ... stayed in school longer. An increase of 3.5 percent ...
Breaking Medicine News(10 mins):Health News:Couple Sues Over Alleged Cancer Risk Associated with use of a Power Morcellator During the Woman's Laparoscopic Fibroid Removal Procedure, Parker Waichman Comments 2Health News:Couple Sues Over Alleged Cancer Risk Associated with use of a Power Morcellator During the Woman's Laparoscopic Fibroid Removal Procedure, Parker Waichman Comments 3Health News:Couple Sues Over Alleged Cancer Risk Associated with use of a Power Morcellator During the Woman's Laparoscopic Fibroid Removal Procedure, Parker Waichman Comments 4Health News:Couple Sues Over Alleged Cancer Risk Associated with use of a Power Morcellator During the Woman's Laparoscopic Fibroid Removal Procedure, Parker Waichman Comments 5Health News:Shoulder Surgery Gets NFL Players Back in the Game 2Health News:Are You Tweeting Your Marriage Away? 2Health News:Are You Tweeting Your Marriage Away? 3Health News:Cultured CTCs reveal genetic profile, potential drug susceptibility of breast cancer cells 2Health News:Cultured CTCs reveal genetic profile, potential drug susceptibility of breast cancer cells 3Health News:Want a higher GPA in college? Join a gym 2
... trial results performed by the Radiation Therapy Oncology ... absence (co-deletion) of chromosomes 1p and 19qhave definitive ... of adult patients with pure and mixed anaplastic ... associated with a substantially better prognosis and near-doubling ...
... 30 per cent of patients hospitalized after a stroke develop ... Researchers found patients who experience delirium after stroke are ... to be discharged to a long-term care facility, nursing home ... recognition and prevention of delirium are important for a quick ...
... HealthDay Reporter , THURSDAY, Jan. 19 (HealthDay News) -- ... child between 2004 and 2008 did not use birth control, and ... a new government study finds. Although the number of teens ... years, the U.S. teen birth rate is still the highest of ...
... now well established, a growing body of research also suggests ... developmental disorder affecting nearly one in 100 children. Using a ... weight is an important environmental factor contributing to the risk ... discordant twins -- twin pairs in which only one twin ...
... THURSDAY, Jan. 19 (HealthDay News) -- Amid hints that statins ... preventing or treating certain types of cancer, new research sheds ... cancer in its tracks among certain women. The ... cells, but some women with breast cancer have mutant forms ...
... gene known as the guardian of the genome is ... aggressive types of cancer, scientists at the European Molecular ... and the University Hospital, all in Heidelberg, Germany, have ... , also presents the first whole genome sequence of ...
Cached Medicine News:Health News:Abnormal chromosome indicator of treatment and outcome in patients with rare brain tumor 2Health News:Abnormal chromosome indicator of treatment and outcome in patients with rare brain tumor 3Health News:Study finds delirium after stroke linked to poorer outcomes for patients 2Health News:More Than Half of Teens Who Gave Birth Weren't Using Contraception: CDC 2Health News:More Than Half of Teens Who Gave Birth Weren't Using Contraception: CDC 3Health News:Another clue in the mystery of autism 2Health News:Study Hints That Statins Might Fight Breast Cancer 2Health News:Rigged to explode? 2Health News:Rigged to explode? 3
(Date:7/10/2014)... July 10, 2014 Yesterday, former Congressman ... medical device manufacturing facility. Rep. Kennedy and ... monitors facilitate cutting-edge research in neurological disease and ... mental health advocate, Garen Staglin , created ... fostering fundamental changes that will radically accelerate the ...
(Date:7/10/2014)...  Valeant Pharmaceuticals International, Inc. (NYSE: VRX ... the sale to Galderma of all rights to Restylane, ... Valeant for $1.4 billion in cash, pursuant to the ... its acquisition of Galderma. "We are ... a company that is firmly committed to the aesthetic ...
(Date:7/10/2014)... 2014  Decision Resources Group finds that while ... specialists are willing to prescribe Durata,s Dalvance (dalbavancin) ... as OPAT, approximately two-thirds of the respondents reported ... hospital inpatients. However, our findings indicate that nearly ... on OPAT following hospital discharge, and most are ...
Breaking Medicine Technology:Representative Patrick Kennedy visits Moberg's medical device facility to discuss improvement in brain injury care 2Long-Acting Antibiotics Offering Once-Weekly Dosing Will See Favorable Uptake and Use as Outpatient Parenteral Antimicrobial Therapy (OPAT) 2Long-Acting Antibiotics Offering Once-Weekly Dosing Will See Favorable Uptake and Use as Outpatient Parenteral Antimicrobial Therapy (OPAT) 3
... Feb. 9, 2011 Reportlinker.com announces that a ... catalogue: European Market for Dental ... http://www.reportlinker.com/p0377961/European-Market-for-Dental-Prosthetics-and-CAD/CAM-Devices-2011.html In 2010, ... crowns, bridges and dentures, were valued at over ...
... 2011 Protect Pharmaceutical Corporation (OTC Bulletin Board: ... of two patents and patents-applications to Grunenthal GmbH, a German ... discovery and research. The patent portfolio includes innovative pain drugs ... Ram Sesha, Protect,s Chief Operating Officer, said, "We are ...
Cached Medicine Technology:Reportlinker Adds European Market for Dental Prosthetics and CAD/CAM Devices 2011 2Protect Pharma Sells Patent Portfolio to Grunenthal GmbH 2
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
Medicine Products: