Navigation Links
Cyclosporine Eye Drops a Good Deal for Dry Eye

Immunosuppressant works where other lubricants fail, study shows

TUESDAY, Feb. 10 (HealthDay News) -- Eye drops that contain the immunosuppressant drug cyclosporine may be a cost-effective treatment for dry eye syndrome that doesn't respond to other therapies, a new study suggests.

Dry eye occurs in 15 percent to 34 percent of older people, according to background information in the study. Cyclosporine is used to treat arthritis and psoriasis, and to reduce organ transplant rejections.

"Patients with dry eye syndrome have more difficulty reading, carrying out professional work, using a computer, watching television and driving compared with those without dry eyes," wrote Dr. Melissa M. Brown, of the Center for Value-Based Medicine and the University of Pennsylvania School of Medicine, and colleagues.

The researchers gave eye drops containing a 0.5 percent emulsion of cyclosporine to patients with moderate to severe dry eye syndrome that didn't respond to conventional therapy. In terms of quality of life, the cyclosporine drops offered 4.3 percent more improvement than eye drops containing only lubricant and 7.1 percent more improvement than no treatment.

The total direct medical cost of the cyclosporine eye drops was $1,834. However, 24.5 percent of treated workers will return to full productivity, which means there's an estimated $1,236 gain associated with treatment, reducing the net cost to $598, the researchers calculated.

The cost to society for treatment with the cyclosporine eye drops was $34,953 more per quality-adjusted life year (a combination of quality and quantity of life) than the lubricant eye drops alone. That's well below the conventional standard of $50,000 per quality-adjusted life year widely considered to be cost-effective, Brown and colleagues said.

The study, which received funding from Allergan Inc., was published in the February issue of the Archives of Ophthalmology.

More information

The MedlinePlus Medical Encyclopedia has more about dry eye.

-- Robert Preidt

SOURCE: JAMA/Archives journals, news release, Feb. 9, 2009

Copyright©2009 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. New buffer resists pH change, even as temperature drops
2. Over-the-counter eardrops may cause hearing loss or damage
3. Over-the-counter eardrops may cause hearing loss or damage
4. Drops of Fatty Acid Curb Symptoms of Dry Eye Syndrome
5. Use of Methamphetamine Among U.S. Workers and Job Applicants Drops 22 Percent in 2007 and Cocaine Use Slows Dramatically, Reports Quest Diagnostics
6. Kidney Foundation Drops Fluoridation Support
7. Number of Uninsured Americans Drops
8. U.S. Cancer Rate-Death Rate Combo Drops for 1st Time
9. Cancer incidence and mortality drops among American men and women, according to annual report
10. Hospitals demonstrate surgical safety checklist drops deaths and complications by more than a third
11. Texas Employment Report: Employee Confidence Index Drops
Post Your Comments:
Related Image:
Cyclosporine Eye Drops a Good Deal for Dry Eye
(Date:11/24/2015)... , ... November 24, 2015 , ... ... the Business Action on Health Awards, bestowed annually to the world’s best corporate-supported ... commended companies at Global Health Council’s Landscape Symposium held in Washington D.C and ...
(Date:11/24/2015)... ... 2015 , ... The OSHA Training Center at Chabot-Las ... in Northern California, is calling on retail employers to implement safety measures to ... volume of sales and shoppers rapidly expands, retailers are strongly encouraged to develop ...
(Date:11/24/2015)... ... , ... There’s nothing better than giving the gift of green this holiday ... , This year, gardens are popping up in the most unexpected places. A variety ... Gardens’ African Keyhole Garden Bed ($499) , Water conscious gardeners – and that should ...
(Date:11/24/2015)... ... November 24, 2015 , ... Wireless Analytics, an ... announced new 24-hour weekday support capability. The “all hours” offering was introduced ... international customers, and to enhance after-hours support available in the US. , Available ...
(Date:11/24/2015)... ... , ... Take the audience on a journey with TransFrame Cloud from Pixel Film ... images without ever setting a single keyframe in Final Cut Pro X. Design smooth and ... to change the angle and depth of field to create a unique viewing perspective. , ...
Breaking Medicine News(10 mins):
(Date:11/24/2015)... Nov. 24, 2015  Figure 1, a free mobile-first ... medical cases, has launched a new completely redesigned web ... version allows radiologists, who work primarily on a desktop, ... engage with its radiologist user base, Figure 1 is ... North America (RSNA) Annual Meeting. ...
(Date:11/24/2015)... , Nov. 24, 2015  Family Rentals, a ... announced the launch of their newly designed, mobile-responsive ... --> Logo ... --> --> Now, renting essential ... and vacation, just got a whole lot easier ...
(Date:11/24/2015)... -- The uptake of recently approved and pipeline premium products ... market growth to 2021, says GBI Research . ... for Type 1 Diabetes Mellitus (T1DM), will be a key driver of ... --> The uptake of recently approved and pipeline premium ... of market growth to 2021, says GBI Research ...
Breaking Medicine Technology: