Navigation Links
Current screening test for prediabetes in children misses the diagnosis too often

Obese children, who are at increased risk for prediabetes and type 2 diabetes, may not be getting the most appropriate test to screen for these conditions, a new Canadian study found. Results were presented Sunday, June 15, at The Endocrine Society's 90th Annual Meeting in San Francisco.

The standard screening test for high blood sugar in children with risk factorsa blood test called the fasting plasma (or blood) glucose testidentified nearly 3 times fewer the children with prediabetes than did a longer blood test, said the study's lead author.

Katherine Morrison, MD, from the pediatrics department of McMaster University, Hamilton, Ontario, said the more accurate test was the glucose stress test, also called the oral glucose tolerance test. This test takes longer because the patient has blood drawn after fasting and again 2 hours after drinking a sugary solution.

Compared with the glucose stress test, the fasting blood glucose test also was not as sensitive in detecting metabolic syndrome. This syndrome is a cluster of risk factors for heart disease and diabetes, including a high blood sugar level.

"Prediabetes and metabolic syndrome are common in obese children but are not readily identified with the currently recommended test," Morrison said. "They require a glucose stress test."

The authors studied 172 obese children, ages 5 to 17, who joined a program to help attain a healthy weight. All children had evaluation of risk factors for diabetes (or its precursor, prediabetes) and metabolic syndrome, including testing of blood sugar. Using the glucose stress test, the researchers found that 25 percent of the children met the diagnostic criteria for prediabetes. But when they relied on results of the fasting blood glucose test, as recommended by the American and Canadian diabetes associations, they found that only 8 percent of the children had prediabetes.

"A large proportion of the children with prediabetes would not have had their condition recognized," Morrison said.

The same was true for the metabolic syndrome. Of the children in the study, 12.8 percent had a diagnosis of this syndrome (based on International Diabetes Federation pediatric criteria) using the glucose stress test, compared with just 5.2 percent using the standard test, the authors reported.

Prediabetes and the metabolic syndrome usually cause no obvious symptoms. Early detection is important because changes in diet, regular exercise, and moderate weight loss can help prevent or delay diabetes and the metabolic syndrome. Although adults receive diabetes screening with either blood test, children typically do not get the 2-hour glucose stress test, Morrison said.

"The commonest reasons are the increased time, inconvenience, and cost required for 2-hour testing," she said. "But this research suggests that the recommended test for screening obese children for prediabetes and metabolic syndrome should be changed."


Contact: Aaron Lohr
The Endocrine Society

Related medicine news :

1. Genomics of Cardiovascular Disease: Current Clinical Applications
2. Combination of 2 novel anti-cancer agents may help fight CML resistant to current therapy
3. Current vitamin D recommendations fraction of safe, perhaps essential levels for children
4. A New Report on Home Telehealth and Remote Patient Monitoring Says Current Market is Close to $5.6 billion and Growth of Up to 70% is Expected to Continue Over the Next Few Years
5. Forty-Five Percent of U.S. Employees Have Gained Weight at Their Current Jobs, Study Finds
6. Current Trends in Arm Lift Surgery
7. Hahnemann University Hospital and St. Christophers Hospital for Children Extend Current Agreement With Independence Blue Cross
8. Current Flu Season Worst in 4 Years
9. Law Offices of Howard G. Smith Announces Investigation on Behalf of Current and Former Employees of Inverness Medical Innovations, Inc. Who Invested in the Inverness Medical Innovations, Inc. Employee Savings Plan
10. Keith Denner Extends Current Technologys Chairman and CEO Options
11. Law Offices of Howard G. Smith Announces Investigation on Behalf of Current and Former Employees of Merck & Co., Inc. Who Invested in the Merck & Co., Inc. Employee Savings and Security Plan
Post Your Comments:
(Date:12/1/2015)... D.C. (PRWEB) , ... December 01, 2015 , ... ... updated, comprehensive website detailing the important role that meat and poultry play ... in meat and poultry, a nutrition quiz where visitors can check their “meat ...
(Date:12/1/2015)... ... December 01, 2015 , ... Integrated Rental Services (“Integrated ... Industries International, LLC (“JII”). , With support from JII, Integrated Rental is poised ... hospitals, surgery centers, clinics, research labs and medical facilities across the United States. ...
(Date:12/1/2015)... ... 01, 2015 , ... Califia Farms , one of the fastest growing ... won top honors in Beverage World Magazine’s Global Packaging Design Awards, taking home the ... been selected as a 2015 U.S.A. Taste Champion in the American Masters of Taste ...
(Date:12/1/2015)... ... December 01, 2015 , ... December ... seen vast improvements in scientific research and discoveries, leading us to better understand ... and relief to those affected by HIV/AIDS. Mediaplanet’s cross-platform edition of “World AIDS ...
(Date:12/1/2015)... ... December 01, 2015 , ... The importance of ... is the focus of numerous abstracts accepted for presentation here, at the 101st ... Nine abstracts highlight the use of Volpara Solutions’ quantitative breast imaging software tools ...
Breaking Medicine News(10 mins):
(Date:12/1/2015)... N.J. , Dec. 1, 2015 ... held in San Francisco, CA ... solutions to the coronary marketplace. During a satellite ... in Stent Design to Minimize Restenosis", a renowned ... currently available Medinol NIRxcell™ CoCr Coronary Stent System ...
(Date:12/1/2015)... 2015 Relmada Therapeutics, Inc. (OTCQB: RLMD), a clinical-stage ... announced today that the company will present at the LD ... at the Luxe Sunset Boulevard Hotel in Los ... Relmada Therapeutics, will present on Thursday, December 3, at 9:00 ... . Please register at least 10 minutes prior to the ...
(Date:12/1/2015)...  InCarda Therapeutics, Inc. (InCarda), a privately-held biopharmaceutical company ... cardiovascular conditions via the inhalation route, today announced that ... Australia . InCarda is planning to undertake its ... in the first half of 2016. The company ... Adelaide and Melbourne.  In addition, ...
Breaking Medicine Technology: