Navigation Links
Current screening test for prediabetes in children misses the diagnosis too often
Date:6/15/2008

Obese children, who are at increased risk for prediabetes and type 2 diabetes, may not be getting the most appropriate test to screen for these conditions, a new Canadian study found. Results were presented Sunday, June 15, at The Endocrine Society's 90th Annual Meeting in San Francisco.

The standard screening test for high blood sugar in children with risk factorsa blood test called the fasting plasma (or blood) glucose testidentified nearly 3 times fewer the children with prediabetes than did a longer blood test, said the study's lead author.

Katherine Morrison, MD, from the pediatrics department of McMaster University, Hamilton, Ontario, said the more accurate test was the glucose stress test, also called the oral glucose tolerance test. This test takes longer because the patient has blood drawn after fasting and again 2 hours after drinking a sugary solution.

Compared with the glucose stress test, the fasting blood glucose test also was not as sensitive in detecting metabolic syndrome. This syndrome is a cluster of risk factors for heart disease and diabetes, including a high blood sugar level.

"Prediabetes and metabolic syndrome are common in obese children but are not readily identified with the currently recommended test," Morrison said. "They require a glucose stress test."

The authors studied 172 obese children, ages 5 to 17, who joined a program to help attain a healthy weight. All children had evaluation of risk factors for diabetes (or its precursor, prediabetes) and metabolic syndrome, including testing of blood sugar. Using the glucose stress test, the researchers found that 25 percent of the children met the diagnostic criteria for prediabetes. But when they relied on results of the fasting blood glucose test, as recommended by the American and Canadian diabetes associations, they found that only 8 percent of the children had prediabetes.

"A large proportion of the children with prediabetes would not have had their condition recognized," Morrison said.

The same was true for the metabolic syndrome. Of the children in the study, 12.8 percent had a diagnosis of this syndrome (based on International Diabetes Federation pediatric criteria) using the glucose stress test, compared with just 5.2 percent using the standard test, the authors reported.

Prediabetes and the metabolic syndrome usually cause no obvious symptoms. Early detection is important because changes in diet, regular exercise, and moderate weight loss can help prevent or delay diabetes and the metabolic syndrome. Although adults receive diabetes screening with either blood test, children typically do not get the 2-hour glucose stress test, Morrison said.

"The commonest reasons are the increased time, inconvenience, and cost required for 2-hour testing," she said. "But this research suggests that the recommended test for screening obese children for prediabetes and metabolic syndrome should be changed."


'/>"/>

Contact: Aaron Lohr
alohr@endo-society.org
240-482-1380
The Endocrine Society
Source:Eurekalert

Related medicine news :

1. Genomics of Cardiovascular Disease: Current Clinical Applications
2. Combination of 2 novel anti-cancer agents may help fight CML resistant to current therapy
3. Current vitamin D recommendations fraction of safe, perhaps essential levels for children
4. A New Report on Home Telehealth and Remote Patient Monitoring Says Current Market is Close to $5.6 billion and Growth of Up to 70% is Expected to Continue Over the Next Few Years
5. Forty-Five Percent of U.S. Employees Have Gained Weight at Their Current Jobs, CareerBuilder.com Study Finds
6. Current Trends in Arm Lift Surgery
7. Hahnemann University Hospital and St. Christophers Hospital for Children Extend Current Agreement With Independence Blue Cross
8. Current Flu Season Worst in 4 Years
9. Law Offices of Howard G. Smith Announces Investigation on Behalf of Current and Former Employees of Inverness Medical Innovations, Inc. Who Invested in the Inverness Medical Innovations, Inc. Employee Savings Plan
10. Keith Denner Extends Current Technologys Chairman and CEO Options
11. Law Offices of Howard G. Smith Announces Investigation on Behalf of Current and Former Employees of Merck & Co., Inc. Who Invested in the Merck & Co., Inc. Employee Savings and Security Plan
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/5/2016)... ... ... Will Never Be The Same” is a fictional tale about growing up with the ... the creation of published author, Kim T. Briggs, a self-described “big kid” who has ... and philosophy from Judson University in Elgin, Illinois. Having written numerous Christian drama skits ...
(Date:12/5/2016)... (PRWEB) , ... December 05, 2016 , ... ... ability of physical therapist assistants, under direct supervision of a licensed physical therapist, ... physical therapy receives a consultation and treatment plan from a licensed physical therapist ...
(Date:12/5/2016)... IL (PRWEB) , ... December 05, 2016 , ... The ... to the individual looking to buy neoprene knee sleeves for lifting and ... The design focuses heavily on two main aspects to provide a higher quality knee ...
(Date:12/5/2016)... ... December 05, 2016 , ... ... an excellent way to ensure moisture measurements are consistently correct. However, regular ... , Now, METTLER TOLEDO offers a solution: SmartCal™ . This ...
(Date:12/5/2016)... ... December 05, 2016 , ... ... they have teamed up with The American College of Surgeons (ACS) to provide ... on Trauma, the “Bleeding Control Basic” course is a pilot program that fulfills ...
Breaking Medicine News(10 mins):
(Date:12/5/2016)... PARSIPPANY, N.J. , Dec. 5, 2016 ... today announced preliminary safety and efficacy data from ... oral selective MDM2 inhibitor, suggesting that DS-3032 may ... relapsed/refractory acute myeloid leukemia (AML) and high-risk myelodysplastic ... part of the phase 1 study of DS-3032 were ...
(Date:12/5/2016)... , Dec. 5, 2016 Eisai Inc. announced ... the 2016 Annual Meeting of the American Epilepsy Society ... is indicated as an adjunctive therapy for the treatment ... generalized seizures and primary generalized tonic-clonic seizures (PGTC) in ... and older. Please see Important Safety Information for FYCOMPA, ...
(Date:12/5/2016)... BioLineRx Ltd. (NASDAQ/TASE: BLRX), a clinical-stage ... candidates, presents positive Phase 2a correlative data, as well as ... at the ongoing 58th American Society of Hematology (ASH) Annual ... . ... As previously announced, in ...
Breaking Medicine Technology: