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CureDM Awarded 2009 Diabetes Product Innovation of the Year by Frost and Sullivan
Date:9/9/2009

which contain all of the hormone secreting cell types required for normal glucose metabolism, only one of which is the beta cell type that secretes insulin. Replacement of insulin alone does not reverse the pathological state.

CureDM's technology, Pancreate(TM) targets this causative aspect of the disease by its inherent mechanism of action to repopulate the pancreas with new islet structures by a process known as islet neogenesis. Based on animal and isolated human tissue studies, reestablishment of new islet structures can occur in as little as 2-3 weeks of treatment with Pancreate(TM) resulting in concomitant reduction or elimination of insulin requirements. The company was awarded a Composition of Matter patent in 2008 by the USPTO for the structure and use of Pancreate(TM) in diabetes and related disorders.

"By working to reverse the disorder, CureDM's Pancreate(TM) is a fine example of innovation and forward thinking in the way we go about treating diabetes today," said Frost & Sullivan's K.N. Prema.

Pancreate(TM) is currently in late stage preclinical development and is expected to enter clinical trials in early 2010 for both, type 1 and type 2 diabetic patients.

About CureDM

CureDM is a biopharmaceutical company focusing on Diseases of Metabolism. CureDM has developed a proprietary platform technology using genomics and proteomics to identify bioactive components of gene products that are fundamental to address unmet medical needs. CureDM's initial focus is in the therapeutic areas of diabetes and obesity. Pancreate(TM) also known as Human proIslet Peptide (HIP) is a 14-amino acid, stabilized human peptide that stimulates the signal pathways that induce new islet formation in the pancreas, without the use of stem cells. Pancreate(TM) creates new insulin-producing beta cells by generating new islets that contain alpha, beta, gamma and delta cells, all of
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SOURCE CureDM, Inc.
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