Navigation Links
Curcumin may inhibit nicotine-induced activation of head and neck cancers
Date:10/4/2009

San Diego, CA Curcumin, the compound that gives curry powder its yellow/orange color, may inhibit the adverse effects of nicotine in patients with head and neck cancer who continue to smoke.

In a paper presented at the 2009 American Academy of Otolaryngology Head and Neck Surgery Foundation (AAO-HNSF) Annual Meeting & OTO EXPO in San Diego, researchers examined the effects of curcumin on head and neck squamous cell carcinoma (HNSCC) growths. The study used an in vitro model of a variety of head and neck cancer cell lines. To mimic the clinical situation, HNSCC cells were pre-treated with curcumin and then nicotine was introduced. The results of the studies showed that the curcumin was able to block the nicotine from activating cancer causing cells.

Annually there are approximately 40,000 new cases of head and neck cancers and 13,000 deaths in the U.S. and 500,000 new cases worldwide. Recurrence of these cancers are high because many patients continue to smoke after successful treatment. Also, former smokers often use nicotine replacement therapy as an aid for successful tobacco cessation.

Although nicotine itself has not been shown to be carcinogenic, it has been shown to encourage the cancer-forming process. The researchers sought a safe, bioactive food compound that could be used not only as a chemopreventive agent but could also block the harmful effects of nicotine.

The results may help to discover additional therapies for cancer prevention and treatment.


'/>"/>

Contact: Jessica Mikulski
newsroom@entnet.org
703-535-3762
American Academy of Otolaryngology -- Head and Neck Surgery
Source:Eurekalert

1

GOOD

Page: 1

Related medicine news :

1. HerbalScience Research Demonstrates that Optimized Turmeric Extract Inhibits Amyloid-Beta Accumulation, a Hallmark of Alzheimers Disease
2. Inhibition of NF-kappa B, a key inflammatory protein, reduced radiation toxicity in zebrafish
3. Prodrug could help curb skin toxicity related to EGFR-inhibiting cancer drugs
4. Catalyst Pharmaceutical Partners Licenses Exclusive Rights to New Class of GABA Aminotransferase Inhibitors From Northwestern University
5. HerbalScience Research Identifies Key Bioactives in Nettle Extract That Inhibit Inflammation Associated with Seasonal Allergies
6. Surveyed Physicians Will Treat Over 50 Percent of Hepatitis C Genotype 1-Infected Patients With the Protease Inhibitor Telaprevir
7. HIV integrase inhibitor effective for patients beginning antiretroviral treatment
8. JNCI news brief: Antibody linked to chemotherapy drug inhibits ovarian cancer in lab
9. Survey Finds 64% of Americans Unaware Sunscreen Inhibits Vitamin D Production
10. For Treatment of Type 2 Diabetes, 89 Percent of Surveyed Endocrinologists Identify a Need for Additional GLP-1 Analogues and 71 Percent Say the Same About DPP-IV Inhibitors
11. Pharmasset Nominates PSI-938 as a New Nucleotide Analog Inhibitor of Hepatitis C for Preclinical Development
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/22/2013)... next two decades, the cost of treating strokes in ... topping more than $180 billion a year, according to ... an aging population. The report, from the American Heart ... May 22 in the journal Stroke . ... Bruce Ovbiagele, chairman of the department of neurology at ...
(Date:5/22/2013)... (PRWEB) May 22, 2013 Award Presented ... Read the press release here: http://bit.ly/13DkFfk , ... was named “Information Management Product/Service of the Year” at ... March at The Colony Hotel in Palm Beach, Florida. ... virtual data room (VDR) solution that optimizes the ...
(Date:5/22/2013)... (PRWEB) May 22, 2013 Hurricane preparation ... your home. That’s why Amica Insurance is ... for the upcoming hurricane season. , “An important part ... Bryan Cook, a senior assistant vice president at Amica ... is before the threat of a storm.” , Flood ...
(Date:5/22/2013)... loving child care is one of the most important things ... in their search, Paty’s Daycare has launched a new ... and much more. , “Our new website is vibrant, fun ... “Auntie Paty” Sutton, founder of Paty’s Daycare. “Just as you ... the first time that you walk through the front door ...
(Date:5/22/2013)... 2013 Unknown to the citizens of Wichita, ... 30 mph. Minutes before it struck, the city’s warning siren ... This gave them time to reach safety and prevented any ... proud to provide a product that will increase safety in ... SAFEPATH® SP40S Emergency Evacuation System provides employees with the ...
Breaking Medicine News(10 mins):Health News:Cost of Treating Strokes in U.S. Could Soar to $180B Annually by 2030: Report 2Health News:Cost of Treating Strokes in U.S. Could Soar to $180B Annually by 2030: Report 3Health News:Merrill DataSite New Press Release: Merrill DataSite® Virtual Data Room Honored as “Information Management Product/Service of the Year” 2Health News:Merrill DataSite New Press Release: Merrill DataSite® Virtual Data Room Honored as “Information Management Product/Service of the Year” 3Health News:Reviewing Insurance Policies: a Key Part of Hurricane Preparations 2Health News:Paty’s Daycare Launches New Website to Connect with Parents in Need of Nurturing Child Care 2Health News:Telcom & Data Introduces Wheelock SAFEPATH® SP40S Emergency Evacuation System, An Effective Office Tool to Protect Employees from Severe Weather Threats 2
... studies published in the current issue of Cell ... for treating diabetes. Researchers in Milan, Italy re-examine the ... and islet cell regeneration and Canadian researchers offer improved ... Both studies are in the current issue of ...
... HealthDay Reporter , THURSDAY, Feb. 17 (HealthDay News) -- ... the age of 2 arrive in emergency rooms with injuries ... shows. Most of these injuries involve cribs and are ... floor, said the researchers from Nationwide Children,s Hospital in Columbus, ...
... Feb. 17 (HealthDay News) -- Arthritis affected about 3.1 million ... there were wide variations in arthritis rates among Hispanic subgroups, ... of arthritis ranged from a low of 11.7 percent among ... Ricans, according to the analysis of National Health Interview Survey ...
... use does not appear to increase the risk of ... by University of Manchester scientists suggests. The researchers ... National Statistics to look at trends in rates of ... 2007. The study, published in the journal ...
... CHICAGOAfraid of becoming disabled in old age, not being able ... Staying physically active before symptoms set in could help. ... and taking overnight trips. According to research conducted at ... associated with a decreased risk of becoming disabled. The ...
... Institute and the University of Pennsylvania School of Medicine ... physicians with the first reliable blood test to predict ... 16 issue of the Journal of Proteome Research ... of clinical samples, published recently in the journal ...
Cached Medicine News:Health News:Researchers work at the frontiers of islet cell transplantation 2Health News:Researchers work at the frontiers of islet cell transplantation 3Health News:Crib Injuries Land Thousands of Toddlers in ER Each Year 2Health News:Crib Injuries Land Thousands of Toddlers in ER Each Year 3Health News:3.1 Million Hispanic Americans Struggle With Arthritis 2Health News:Cell-phone use not related to increased brain cancer risk 2Health News:Higher levels of social activity decrease the risk of developing disability in old age 2Health News:Biomarker discovery may lead to reliable blood test for ectopic pregnancy 2Health News:Biomarker discovery may lead to reliable blood test for ectopic pregnancy 3
(Date:5/22/2013)... , May 22, 2013  Grifols, a global healthcare ... presented results from a study demonstrating that a higher ... [Human]) increased levels of the alpha 1 protein ... levels that are considered within the normal range for ... in which low levels of the alpha 1 ...
(Date:5/22/2013)... 2013  Ohr Pharmaceutical Inc. (OTCQB: OHRP), a pharmaceutical ... unmet medical needs, today announced the appointment of ... its Board of Directors. Dr. Almenoff has extensive experience ... stage drug development. "We are delighted ... Irach Taraporewala, CEO of Ohr Pharmaceutical. "She offers tremendous ...
(Date:5/22/2013)... SALT LAKE CITY , May 22, 2013 ... VAR ) today announced it received 510(k) clearance ... for Varian,s diagnostic X-ray image processing workstation that ... capabilities on one platform.  Varian,s Nexus DRF Digital ... with a variety of image receptors, including CCD ...
Breaking Medicine Technology:Grifols study demonstrates higher dose of PROLASTIN-C increases levels of alpha1-PI to within normal range in patients with AAT deficiency 2Grifols study demonstrates higher dose of PROLASTIN-C increases levels of alpha1-PI to within normal range in patients with AAT deficiency 3Grifols study demonstrates higher dose of PROLASTIN-C increases levels of alpha1-PI to within normal range in patients with AAT deficiency 4Ohr Pharmaceutical Appoints June S. Almenoff to Board of Directors 2Ohr Pharmaceutical Appoints June S. Almenoff to Board of Directors 3Varian Medical Systems Receives FDA 510(k) Clearance of its Nexus DRF Digital X-Ray Imaging System 2
... 4, 2011 Bioness Inc. today ... of the FASTEST study to further examine the impact of ... drop as a result of stroke. The FASTEST study aims ... System over standard therapy with an ankle-foot orthosis (AFO), and ...
... Inc. (NASDAQ: NBIX ) today announced that it ... for elagolix and next-generation Gonadotropin Releasing Hormone (GnRH) Receptor Antagonists. ... with the FDA, the outcome of which generated a $20 ... event brings the total milestones achieved by the Company in ...
Cached Medicine Technology:Bioness Inc. Announces Completion of Enrollment in Its FASTEST L300 Study 2Neurocrine Biosciences Receives Second Milestone Payment of $20 Million Under Abbott Collaboration Agreement 2
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
Medicine Products: