Navigation Links
Curcumin may inhibit nicotine-induced activation of head and neck cancers
Date:10/4/2009

San Diego, CA Curcumin, the compound that gives curry powder its yellow/orange color, may inhibit the adverse effects of nicotine in patients with head and neck cancer who continue to smoke.

In a paper presented at the 2009 American Academy of Otolaryngology Head and Neck Surgery Foundation (AAO-HNSF) Annual Meeting & OTO EXPO in San Diego, researchers examined the effects of curcumin on head and neck squamous cell carcinoma (HNSCC) growths. The study used an in vitro model of a variety of head and neck cancer cell lines. To mimic the clinical situation, HNSCC cells were pre-treated with curcumin and then nicotine was introduced. The results of the studies showed that the curcumin was able to block the nicotine from activating cancer causing cells.

Annually there are approximately 40,000 new cases of head and neck cancers and 13,000 deaths in the U.S. and 500,000 new cases worldwide. Recurrence of these cancers are high because many patients continue to smoke after successful treatment. Also, former smokers often use nicotine replacement therapy as an aid for successful tobacco cessation.

Although nicotine itself has not been shown to be carcinogenic, it has been shown to encourage the cancer-forming process. The researchers sought a safe, bioactive food compound that could be used not only as a chemopreventive agent but could also block the harmful effects of nicotine.

The results may help to discover additional therapies for cancer prevention and treatment.


'/>"/>

Contact: Jessica Mikulski
newsroom@entnet.org
703-535-3762
American Academy of Otolaryngology -- Head and Neck Surgery
Source:Eurekalert

Page: 1

Related medicine news :

1. HerbalScience Research Demonstrates that Optimized Turmeric Extract Inhibits Amyloid-Beta Accumulation, a Hallmark of Alzheimers Disease
2. Inhibition of NF-kappa B, a key inflammatory protein, reduced radiation toxicity in zebrafish
3. Prodrug could help curb skin toxicity related to EGFR-inhibiting cancer drugs
4. Catalyst Pharmaceutical Partners Licenses Exclusive Rights to New Class of GABA Aminotransferase Inhibitors From Northwestern University
5. HerbalScience Research Identifies Key Bioactives in Nettle Extract That Inhibit Inflammation Associated with Seasonal Allergies
6. Surveyed Physicians Will Treat Over 50 Percent of Hepatitis C Genotype 1-Infected Patients With the Protease Inhibitor Telaprevir
7. HIV integrase inhibitor effective for patients beginning antiretroviral treatment
8. JNCI news brief: Antibody linked to chemotherapy drug inhibits ovarian cancer in lab
9. Survey Finds 64% of Americans Unaware Sunscreen Inhibits Vitamin D Production
10. For Treatment of Type 2 Diabetes, 89 Percent of Surveyed Endocrinologists Identify a Need for Additional GLP-1 Analogues and 71 Percent Say the Same About DPP-IV Inhibitors
11. Pharmasset Nominates PSI-938 as a New Nucleotide Analog Inhibitor of Hepatitis C for Preclinical Development
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... Nevada (PRWEB) , ... October 13, 2017 , ... ... Hemp CBD Oil utilizing Purzorb™ technology. Applying the Purzorb™process to full spectrum CBD oil ... required and providing a CBD form that can be easily incorporated into liquid products, ...
(Date:10/13/2017)... , ... October 13, 2017 , ... Many families have ... many long-term care insurance companies have a waiver for care if the client has ... period, when the family pays for care, is often waived, so the benefits from ...
(Date:10/13/2017)... Texas (PRWEB) , ... October 13, 2017 , ... Yisrayl ... this week that explains one of the most popular and least understood books in ... like cryptic and puzzling descriptions that have baffled scholars for centuries. Many have tossed ...
(Date:10/13/2017)... ... 2017 , ... “America On The Brink”: the Christian history of the United ... the creation of published author, William Nowers. Captain Nowers and his wife, Millie, ... spent thirty years in the Navy. Following his career as a naval aviator ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... meet the demand of today’s consumer and regulatory authorities worldwide. From Children’s to ... and tested to meet the highest standard. , These products are also: ...
Breaking Medicine News(10 mins):
(Date:10/11/2017)... Oct. 11, 2017  BioPharmX Corporation (NYSE MKT: BPMX) ... developed an innovative way to use nonlinear optical imaging ... of new drugs. ... Conference will show how researchers from BioPharmX and the ... School used a suite of imaging techniques in what ...
(Date:10/10/2017)...   West Pharmaceutical Services, Inc. (NYSE: WST), ... administration, today shared the results of a study highlighting ... intradermal administration of polio vaccines. The study results were ... 2017 by Dr. Ondrej Mach , Clinical Trials ... (WHO), and recently published in the journal Vaccine. ...
(Date:10/4/2017)... , Oct. 4, 2017 OBP ... self-contained, illuminating medical devices, today announced regulatory approval ... Surveillance Agency (or Agência Nacional de Vigilância Sanitária ... single-use, cordless surgical retractor with integrated LED light ... access, illumination and exposure of a tissue pocket ...
Breaking Medicine Technology: