Navigation Links
Crystal Research Associates, LLC Issues Executive Informational Overview(R) (EIO(R)) on Tapestry Pharmaceuticals, Inc.
Date:9/11/2007

NEW YORK, Sept. 11 /PRNewswire/ -- Crystal Research Associates, LLC announced today that it has issued an Executive Informational Overview(R) (EIO(R)) on Tapestry Pharmaceuticals, Inc. (Nasdaq: TPPH). The full 60-page report can be found at http://www.crystalra.com.

Tapestry Pharmaceuticals, Inc. ("Tapestry" or "the Company") is a biopharmaceutical company developing New Chemical Entities that may be effective in treating a broad spectrum of cancers. The Company's lead compound, TPI 287, is a novel, proprietary, third-generation taxane. Although taxanes have been used as cancer therapies for many years, treatment with these drugs is often plagued by undesirable effects, the most notable of which is the emergence of multi-drug resistance (MDR). To address this, Tapestry is developing TPI 287, which has shown the ability to overcome MDR in preclinical experiments.

In particular, TPI 287 targets MDR-1 (the primary mechanism responsible for tumor resistance to taxanes). TPI 287 has also shown efficacy in preclinical studies in a broad range of cell lines versus comparator drugs. Furthermore, in animal models, TPI 287 has shown greater oral bioavailability than paclitaxel, an approved taxane.

The Company filed an Investigational New Drug (IND) application for TPI 287 with the U.S. Food and Drug Administration (FDA) and commenced two Phase 1 studies, each with a different dosing regimen. The first Phase 1 study, which began in January 2005, employed a Q7D X3 regimen (dosing every seven days for three weeks), while the second Phase 1 study, which started in January 2006, used a Q21D (dosing every 21 days) regimen. The objectives of these Phase 1 trials were to determine the maximum tolerated dose (MTD) to be used in Phase 2 studies as well as to determine the safety, anti-tumor, and pharmacokinetic and pharmacodynamic profiles of TPI 287. In October 2006, the Company reached the MTD of its second Phase 1 trial. The Company is headquartered in Boulder, Colorado, with offices in New Jersey and New York.

About Crystal Research Associates, LLC

Crystal Research Associates, LLC is an independent research firm that provides institutional-quality, fee-based research to small and mid-cap companies. Crystal Research Associates' unique and novel product, the Executive Informational Overview(R) (EIO(R)), is free of investment ratings, target prices, and forward-looking financial models. The EIO(R) presents a crystal clear, detailed report on a company (public or private) in a manner that is easily understood by the Wall Street financial community. The EIO(R) details a company's product/technology/service offerings, market size(s), key intellectual property, leadership, growth strategy, competition, risks, audited financial statements, key events, and other such fundamental information. Crystal Research Associates has offices in New York City, Delray Beach, Montreal, and Toronto. Crystal Research Associates has been compensated by the Company in cash of forty seven thousand five hundred dollars for its services in creating this report, for updates, and for printing costs

Forward-Looking Safe Harbor Statement

Statements in this news release regarding the potential effectiveness of TPI 287 in treating a broad spectrum of cancers and any other statements about the future expectations, beliefs, goals, plans, or prospects expressed constitute forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. Any statements that are not statements of historical fact (including statements containing the words "will," "believes," "plans," "anticipates," "expects," "estimates," and similar expressions) should also be considered to be forward-looking statements. Such forward-looking statements involve known and unknown risks, uncertainties, and other factors that may cause actual results, performance, or achievements to be materially different from the results, performance, or achievements expressed or implied by such forward-looking statements. Such risks, uncertainties, and other factors include risks that clinical trials for TPI 287 will be delayed due to institutional approvals, patient recruitment, formulation and manufacturing difficulties, delays in finalizing and receiving approval of protocols, negotiations with regulatory agencies, or other factors, and that human clinical trials may show that TPI 287 is unsafe and/or ineffective in treating cancer in humans. General implementation risks associated with development of TPI 287 include those that the Company is blocked or limited in the development of TPI 287 because of the intellectual property rights of third parties; that the Company is limited in its ability to obtain, maintain, and enforce its own intellectual property; that development of TPI 287 is delayed or terminated because the costs of further development exceed its value; and that the Company's resources will be insufficient to continue development. Additional information on factors that could affect results and other risks and uncertainties are detailed from time to time in the Company's periodic reports, including Forms 10-K, 10-Q, and any other forms filed by the Company with the Securities and Exchange Commission.

These statements, and other forward-looking statements, are not guarantees of future performance and involve risks and uncertainties. Crystal Research Associates assumes no obligation to update any of the forward-looking statements in this release.


'/>"/>
SOURCE Crystal Research Associates, LLC
Copyright©2007 PR Newswire.
All rights reserved

Related medicine news :

1. Government To Clamp Down On Crystal Meth
2. Insulin Crystals Holds Promise In Diabetes research
3. Does Aspirin Crystallize?
4. Cellulose Nanocrystal Research Paves the Way for Newer Vaccines, Computer Inks
5. Human Membranes Crystal Structure may Help Tailor Asthma Drugs
6. Kidney Stones - Interesting New Research implicates bacteria as its cause
7. Stem cell research- now Nobel Laureates join the debate
8. Researchers urge caution in using ear tube surgery
9. Paracetamol May Cause Live Damage Warns Consumer Education and Research Centre
10. Spouses and other partners lower blood pressure says new research
11. Researchers Scale to assess the Severity of Epilepsy in Kids
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/20/2017)... ... June 20, 2017 , ... Many RNA ... regulatory principles, the research team developed expressRNA, a web platform encompassing computational tools ... reveals at nucleotide resolution the ‘RNA maps’, which demonstrate that RBPs bind to ...
(Date:6/20/2017)... ... 2017 , ... Uniform Advantage (UA), a multi-channel retailer of medical ... create tailored looks and athleisure-inspired outfits. UA Flex fabric is breathable, wrinkle resistant and ... With trendy looks hitting the medical community, UA Flex is for the medical professional ...
(Date:6/20/2017)... ... June 20, 2017 , ... BrightStar Care Centerville/South Dayton, a ... the Joint Commission, which accredits and certifies nearly 21,000 healthcare organizations and programs ... a symbol of quality that reflects an organization’s commitment to meeting certain performance ...
(Date:6/20/2017)... ... 20, 2017 , ... Uniworld Boutique River Cruise Collection recently gave ... boutique ship, S.S. Joie de Vivre . What really sets this ship apart ... River and designed small enough to dock directly in Paris. With The Cruise Web’s ...
(Date:6/20/2017)... ... June 20, 2017 , ... International water ... The Sharon Kleyne Hour Power of Water, Global Climate Change and Your Health ... world’s water crisis and how it affects the human eyes. , According ...
Breaking Medicine News(10 mins):
(Date:6/9/2017)... PALO ALTO, Calif. , June 9, 2017 /PRNewswire/ ... medical device company focused on the design, manufacture, sale ... updated the market on the progress of its commercial ... AeroForm is now available in more than one hundred ... country. AeroForm offers a needle-free alternative ...
(Date:6/8/2017)... MCKINNEY, Texas , June 8, 2017 ... Company"), a leading developer and manufacturer of ... industry, announced today that Cressey & Company ... investment firm, has completed a growth-focused investment ... acquired a majority ownership position from selling ...
(Date:6/5/2017)... June 5, 2017 The Cincinnati ... Diplomat Pharmacy, Inc. (NYSE: DPLO), has been awarded a ... . Results are based on an employee survey ... health and workplace improvement. The survey measures several aspects of ... ...
Breaking Medicine Technology: