Navigation Links
Cross-species transplant in rhesus macaques is step toward diabetes cure for humans
Date:10/18/2007

acaques have each received two transplants of embryonic pancreatic cells. One of the animals has been followed for 23 months after his first transplant, and the amount of insulin he needs to have injected has declined by some 55 percent over baseline levels. The other macaque has been followed for 10 months after his initial transplant, and his need for injected insulin continues to decline over time.

Hammerman and his colleague Sharon Rogers, research instructor in medicine, are leaders in the emerging field of organogenesis, which focuses on growing organs from transplanted embryonic organ precursors known as primordia. Unlike embryonic stem cells, which can become virtually any cell type, primordia are locked into becoming cells of a particular organ.

"We are encouraged by these results," Rogers says. "The absence of a need for immune suppression in diabetic rats gave us hope that we were on the right track. But many findings in rats do not hold true for species that are more closely related to humans, such as non-human primates. This one did."

The team will now determine how best to eliminate the need for injected insulin in the diabetic macaques that receive transplants, thus demonstrating long-term effectiveness of the technique, and establish the absolute safety of pancreatic primordia transplants. If these experiments succeed, the researchers plan to conduct clinical trials in humans with diabetes.

"We hope to find out how to apply our findings to human type 1 and type 2 diabetics because the embryonic pig primordia would represent an unlimited source of tissue for transplantation," Hammerman says.


'/>"/>

Contact: Caroline Arbanas
arbanasc@wustl.edu
314-286-0109
Washington University in St. Louis
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Infant receives first bloodless liver transplant
2. Liver donors can thrive after transplant
3. ATG useful in transplant patients as substitute for steroids
4. Transplant helps diabetes
5. Larynx transplant restores patients voice after 20 years
6. Baby Lennox Gets Liver Transplant
7. Chinese Girl To Undergo Face Transplant Surgery
8. Stem cell transplantation of eye
9. Woman gets cancer from transplanted kidney
10. Parasite infections linked to organ transplants
11. Vitamins enhances recuperation of organ transplant patients
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... January 22, 2015 Padre Murphy's and Owner ... of Pro Player Health Alliance (PPHA). The PPHA's ... in getting everyone, including NFL greats, treated for obstructive sleep ... leading groups supporting the cause in the valley. The most ...
(Date:1/22/2015)... TX (PRWEB) January 22, 2015 The Incredible ... Bodybuilder Ben Pakulski to increase lean muscle by up to ... has caught the attention of HealthyandFitZone.com’s Stan Stevenson, prompting an ... that it is a step-by-step, scientific diet formula that allows ...
(Date:1/22/2015)... 22, 2015 Blue Cross and Blue Shield ... exemplify what it means to “Live Fearless.” , ... to share their stories about how they or someone they ... others by living in the moment. By telling these types ...
(Date:1/22/2015)... York, New York (PRWEB) January 22, 2015 ... http://www.vaginalmeshlawsuit2015.com/ ) in the U.S. District Court, Southern District of ... C.R. Bard, Inc. in that proceeding’s first bellwether trial. In ... request for a new trial after finding that C.R. Bard ...
(Date:1/22/2015)... 22, 2015 A new white paper ... and person-centeredness in the long-term care environment as well ... the continuum. The paper, “The Power of Person-Centeredness in ... and practices of the patient, resident and family experience ...
Breaking Medicine News(10 mins):Health News:Padre Murphy's Holds NFL Retired Players Association Party Star Studded Event With Bud Light and Pro Player Health Alliance Sponsoring 2Health News:Padre Murphy's Holds NFL Retired Players Association Party Star Studded Event With Bud Light and Pro Player Health Alliance Sponsoring 3Health News:The Incredible Bulk: Review Examining Ben Pakulski’s Brand New Bulking Muscle Building Diet Program Released 2Health News:Blue Cross and Blue Shield of Minnesota to Showcase “Faces of Fearless” 2Health News:Court Upholds $2 Million Vaginal Mesh Lawsuit Verdict Levied Against C.R. Bard in First Federal Bellwether Trial, Bernstein Liebhard LLP Reports 2Health News:Court Upholds $2 Million Vaginal Mesh Lawsuit Verdict Levied Against C.R. Bard in First Federal Bellwether Trial, Bernstein Liebhard LLP Reports 3Health News:Court Upholds $2 Million Vaginal Mesh Lawsuit Verdict Levied Against C.R. Bard in First Federal Bellwether Trial, Bernstein Liebhard LLP Reports 4Health News:The Power of Person-Centeredness in Long-Term Care Explored by The Beryl Institute 2Health News:The Power of Person-Centeredness in Long-Term Care Explored by The Beryl Institute 3
... ... everyone will carry their snacks while on the go. KUBBE is the first and ... hassle free. , ... 17, 2010 -- KUBBE is a trendy plastic utility buckle that allows people to carry ...
... , , ... ... ... ...
... ... ... ... ...
... in the March issue of Radiology , researchers from ... have determined that an imaging exam of the heart using ... much as 91 percent less radiation than standard helical CT ... in recent years, due to its diagnostic accuracy in assessing ...
... ... ... ... ...
... ... ... ... , ...
Cached Medicine News:Health News:Pew Report: New Jersey Failing to Address Children's Dental Health Crisis 2Health News:Pew Report: New Jersey Failing to Address Children's Dental Health Crisis 3Health News:Pew Report: New Jersey Failing to Address Children's Dental Health Crisis 4Health News:Pew Report: New Jersey Failing to Address Children's Dental Health Crisis 5Health News:Pew Report: New Jersey Failing to Address Children's Dental Health Crisis 6Health News:Pew Report: New Jersey Failing to Address Children's Dental Health Crisis 7Health News:Pew Report: Connecticut is a National Leader in Addressing Children's Dental Health 2Health News:Pew Report: Connecticut is a National Leader in Addressing Children's Dental Health 3Health News:Pew Report: Connecticut is a National Leader in Addressing Children's Dental Health 4Health News:Pew Report: Connecticut is a National Leader in Addressing Children's Dental Health 5Health News:Pew Report: Connecticut is a National Leader in Addressing Children's Dental Health 6Health News:Pew Report: Connecticut is a National Leader in Addressing Children's Dental Health 7Health News:New cardiac CT technology drastically reduces patient radiation exposure 2Health News:E-Cigarette Maker Green Smoke Tells FDA to Back Off! 2Health News:E-Cigarette Maker Green Smoke Tells FDA to Back Off! 3Health News:E-Cigarette Maker Green Smoke Tells FDA to Back Off! 4Health News:Healthcare Realty Trust Announces Fourth Quarter Results 2Health News:Healthcare Realty Trust Announces Fourth Quarter Results 3Health News:Healthcare Realty Trust Announces Fourth Quarter Results 4Health News:Healthcare Realty Trust Announces Fourth Quarter Results 5Health News:Healthcare Realty Trust Announces Fourth Quarter Results 6Health News:Healthcare Realty Trust Announces Fourth Quarter Results 7Health News:Healthcare Realty Trust Announces Fourth Quarter Results 8Health News:Healthcare Realty Trust Announces Fourth Quarter Results 9Health News:Healthcare Realty Trust Announces Fourth Quarter Results 10Health News:Healthcare Realty Trust Announces Fourth Quarter Results 11Health News:Healthcare Realty Trust Announces Fourth Quarter Results 12Health News:Healthcare Realty Trust Announces Fourth Quarter Results 13Health News:Healthcare Realty Trust Announces Fourth Quarter Results 14Health News:Healthcare Realty Trust Announces Fourth Quarter Results 15
(Date:1/23/2015)... MYERS, Fla. , Jan. 23, 2015  Today the ... of Novartis, Bexsero® for the prevention of serogroup ... 25. Bexsero and Pfizer,s vaccine Trumenba®, which received FDA ... helping prevent this devastating disease. "I ...
(Date:1/23/2015)... Iowa , Jan. 23, 2015  The Partnership to Fight Chronic ... health care leaders and a new study analyzing the ... The PFCD is a nationwide coalition working to educate policy makers ... released at the Capitol was focused on how the ...
(Date:1/23/2015)... 23, 2015 More than a third of reproductive-aged women ... with private insurance, filled a prescription for an opioid pain ... this week,s Morbidity and Mortality Weekly Report (MMWR). ... treat moderate to severe pain.  They are also found in ...
Breaking Medicine Technology:The National Meningitis Association (NMA) Applauds FDA Approval of Second Vaccine To Protect Against Serogroup B Meningococcal Disease 2New research shows Iowa health exchange would benefit from improvements 2New research shows Iowa health exchange would benefit from improvements 3Opioid painkillers widely prescribed among reproductive age women 2Opioid painkillers widely prescribed among reproductive age women 3
... Feb. 17 The United States, fifth hand ... home to Massena, New York this week after ... of Kleinert Kutz and University of Louisville ... UofL hand surgeons performed the Hondusky,s hand transplant ...
... Sanofi Pasteur, the,vaccines division of sanofi-aventis Group (EURONEXT ... is sponsoring a phase II clinical study of a ... causes of,hospital-acquired infection in Europe and North America. , ... the United Kingdom is investigating the,safety and efficacy of ...
Cached Medicine Technology:Fifth U.S. Hand Transplant Patient Heads Home to NY 2Fifth U.S. Hand Transplant Patient Heads Home to NY 3Sanofi Pasteur Starts a Phase II Study of a Vaccine Against Clostridium Difficile 2Sanofi Pasteur Starts a Phase II Study of a Vaccine Against Clostridium Difficile 3Sanofi Pasteur Starts a Phase II Study of a Vaccine Against Clostridium Difficile 4Sanofi Pasteur Starts a Phase II Study of a Vaccine Against Clostridium Difficile 5
Extremely fine straight....
Curved delicate 5 mm blades....
Micro dressing forceps....
... M520 OH3 is a smart ... performance available on the market ... stand. The Leica M520 OH3 ... greatest range of movement and ...
Medicine Products: