Navigation Links
Crohn's & Colitis Foundation Opens DNA Data Bank

Powerful New Resource to Advance Understanding of Disease Genetics

New York, New York (Vocus) September 24, 2009 -- The Crohn's & Colitis Foundation today announced the launch of its DNA Data Bank, a newly created resource containing DNA samples and detailed phenotype data on a large number of Crohn's disease and ulcerative colitis patients. Enhancing research into genetic markers and determinants that affect risk for these diseases (collectively known as inflammatory bowel disease or IBD), is a priority for researchers seeking to understand the underlying disease process in order to improve disease treatment and prevention.

"At the Crohn's & Colitis Foundation we believe that genetic research has the potential to advance our understanding of the etiologies and natural histories of the various forms of Crohn's disease and ulcerative colitis," says Marjorie Merrick, Vice President of Research for the Foundation. "The launch of the DNA Data Bank symbolizes that we are within reach of our long term goal of improving treatment and minimizing the overall impact of Crohn's and colitis."

Affecting over 1.4 million Americans of all ages, lifetime risk for developing IBD is 10 to 20 times higher for close family members (siblings or offspring) of persons with IBD than it is for the general population. This strongly suggests that genetic factors may play an important role in determining whether an individual develops IBD.

Blood samples were obtained from patients with well-characterized Crohn's disease or ulcerative colitis. Samples were then collected from each patient's parents, or, if one or both parents were deceased, from unaffected age- and sex-matched controls sampled from the general population. Immortalized cell lines were produced from most of the blood samples and high-quality DNA was derived primarily from those cell lines. For a small proportion of the samples the patient's cell line immortalization failed and whole genome amplified (WGA) DNA is available instead.

The new databank, which has been made possible through a generous gift from The Donald W. Reynolds Foundation, is available to qualified investigators in the scientific community for innovative studies of genetic markers related to IBD. Interested investigators may view available phenotype data elements, obtain summaries of the numbers of affected patients and family or population controls, and submit research proposals at the DNA Data bank website,

About Crohn's Disease and Ulcerative Colitis
Crohn's disease and ulcerative colitis are painful, medically incurable illnesses that attack the digestive system. Crohn's disease may attack anywhere from the mouth to the anus, while ulcerative colitis inflames only the large intestine (colon). Symptoms may include abdominal pain, persistent diarrhea, rectal bleeding, fever and weight loss. Many patients require hospitalization and surgery. These illnesses can cause severe complications, including colon cancer in patients with long-term disease. Some 1.4 million American adults and children suffer from Crohn's disease or ulcerative colitis, with as many as 150,000 under the age of 18. Most people develop the diseases between the ages of 15 and 35.

About the Crohn's & Colitis Foundation of America
The Crohn's & Colitis Foundation of America's mission is to cure Crohn's disease and ulcerative colitis, and to improve the quality of life of children and adults affected by these diseases. As the largest worldwide funding organization of pediatric IBD programs, the Foundation ranks third among leading health non-profits in the percentage of expense devoted to research toward a cure, with more than 80 cents of every dollar the Foundation spends goes to mission-critical programs. The Foundation consistently meets the standards of organizations that monitor charities, including the Better Business Bureau's Wise Giving Alliance and the American Institute of Philanthropy. For more information, contact the Foundation at 800-932-2423 or visit the CCFA web site at

Ariella Levine
Crohn's & Colitis Foundation

# # #

Read the full story at

Source: PRWeb
Copyright©2009 Vocus, Inc.
All rights reserved  

Related medicine news :

1. Crohn's & Colitis Foundation Encourages More Virtual Event Participants: Thousands Already Helped Foundation Raise Funds for Research & Support Legislation
2. Crohn's & Colitis Foundation Issues Annual Report
3. New Source of Information on Crohn's Disease and Ulcerative Colitis Medications
4. Bruce E. Katz, M.D. of Juva Skin & Laser Center Pioneers "The Madonna Lift" Fractional Eyelift Procedure
5. Luxury Bed Maker Hstens Introduces Mindspa iPhone™ Application
6. Phoenix Children's Hospital Significantly Reduces Costs with Orion Health™ Technology
7. New Poll Shows Values Voters in Lockstep on the ‘Moral Implications' of Health Care Reform
8. Appointment-Plus Introduces Text-Ding™ Automated Text Message Appointment Reminders
9. More Sleep & Less Sex - A Losing Combination
10. LeBow & Associates Moves to New Office in Manhattan
11. Online Sign Making from Just Got Faster, Easier, & Greener with its New Revolutionary System
Post Your Comments:
Related Image:
Crohn's & Colitis Foundation Opens DNA Data Bank 
(Date:11/30/2015)... ... 2015 , ... The Foundation for Breast and Prostate Health ... forces with the award-winning creator and writer of Downton Abbey Julian Fellowes to ... the Union League of Philadelphia. , The benefit, titled “An Evening with ...
(Date:11/30/2015)... ... November 30, 2015 , ... California-based i2i Systems, a pioneer ... that Michigan-based Family Health Center (FHC) has selected i2iTracks as their population health ... awarded the largest Affordable Care Act grant for Federally Qualified Health Centers in ...
(Date:11/30/2015)... ... , ... In an interview with Andy Mitchell of Peconic Bay Medical Center, ... east end. During the broadcast, entitled “Eyes: the Window to the Soul,” Dr. Buono ... and how a visit with his grandmother to her physician put him on a ...
(Date:11/30/2015)... ... November 30, 2015 , ... ... Kreithen”), one of the leading plastic surgery practices in Florida, is proud to ... to consult for surgical innovations giant Ethicon Inc., a Johnson & Johnson Company. ...
(Date:11/30/2015)... ... November 30, 2015 , ... Vasont Systems, a top component ... (VUI) extension unites with Syncro Soft’s latest software update, oXygen XML editor Version ... with the latest release of oXygen® XML editor and the Vasont® CCMS. ...
Breaking Medicine News(10 mins):
(Date:11/30/2015)... Medical Systems (NYSE: VAR ) has signed a Memorandum of ... the largest hospital chain in India , to ... country. The MoU was signed by Dr. K. Prabakar , ... Varian,s India managing director, in ... intends to deploy its Access to Care program by leveraging the ...
(Date:11/30/2015)... NAMUR , Belgium , Nov. 30, ... life sciences company focused on developing blood-based diagnostic tests for ... announced the Company will present at the LD Micro Conference, ... Los Angeles, CA. Attending from VolitionRx will ... and Scott Powell , Vice President of Investor Relations. ...
(Date:11/30/2015)... Mexico Healthcare and Life Sciences Report 2015 . --> ... Pharmaboardroom releases its new 98-page Mexico Healthcare and Life Sciences ... country of over 122 million people. --> Latin ... --> It offers companies, investors, policymakers, and stakeholders with an ... largest pharma and healthcare market in Latin America ...
Breaking Medicine Technology: