Navigation Links
Critical role of one gene to our brain development
Date:3/14/2014

Research from the University of Adelaide has confirmed that a gene linked to intellectual disability is critical to the earliest stages of the development of human brains.

Known as USP9X, the gene has been investigated by Adelaide researchers for more than a decade, but in recent years scientists have begun to understand its particular importance to brain development.

In a new paper published online in the American Journal of Human Genetics, an international research team led by the University of Adelaide's Robinson Research Institute explains how mutations in USP9X are associated with intellectual disability. These mutations, which can be inherited from one generation to the next, have been shown to cause disruptions to normal brain cell functioning.

Speaking during Brain Awareness Week, senior co-author Dr Lachlan Jolly from the University of Adelaide's Neurogenetics Research Program says the USP9X gene has shed new light on the mysteries of brain development and disability.

Dr Jolly says the base framework for the brain's complex network of cells begins to form at the embryo stage.

"Not surprisingly, disorders that cause changes to this network of cells, such as intellectual disabilities, epilepsy and autism, are hard to understand, and treat," Dr Jolly says.

"By looking at patients with severe learning and memory problems, we discovered a gene - called USP9X - that is involved in creating this base network of nerve cells. USP9X controls both the initial generation of the nerve cells from stem cells, and also their ability to connect with one another and form the proper networks," he says.

"This work is critical to understandin
'/>"/>

Contact: Dr. Lachlan Jolly
lachlan.jolly@adelaide.edu.au
61-881-616-363
University of Adelaide
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Critical protein discovered for healthy cell growth in mammals
2. Need for Mosquito Control Becoming More Critical
3. Life Insurance To Cover Funeral Costs Or Critical Illness Plans? What Should Seniors Choose?
4. Is Critical Bench Program The Effective Solution For Building Muscle? – Vinamy
5. Critical Bench: Review Exposes Mike Westerdal’s Muscle and Strength Building Program
6. Middle East Critical Infrastructure Protection (CIP) Market (Technology, Solutions, Services) Worth $13.07 Billion by 2018 - New Report by MarketsandMarkets
7. Human neural stem cells could meet the clinical problem of critical limb ischemia
8. UC Irvine Health Appoints William C. Wilson, MD, as Director of Critical Care Services
9. Global Food Exchange Responds to Critical Need in the Philippines
10. UC Irvine Health Appoints William C. Wilson, MD, as Hospital Director of Critical Care Services, Division of the Department of Anesthesiology & Perioperative Care
11. Discover Innovative Upper Body Exercises With The “Critical Bench” Course – Vkoolelite
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/2/2014)... (HealthDay News) -- Drinking and marijuana may lead to ... study suggests. Researchers analyzed 2007 to 2011 data ... who said they had used alcohol or marijuana at ... was associated with more unsafe driving, damage to relationships ... while under the influence of alcohol, especially among females. ...
(Date:9/2/2014)... apnea, tonsillectomies, hearing loss, head and neck cancers ... Orlando, FL, September 21-24, at the 2014 Annual ... of OtolaryngologyHead and Neck Surgery Foundation (AAO-HNSF), the ... and neck physicians in the world. , Abstracts ... today, and are available online at http://oto.sagepub.com/content/151/1_suppl ...
(Date:9/2/2014)... Last year, SIGVARIS took graduated ... of a luxurious line of graduated compression socks with natural ... COTTON Socks are joining the SIGVARIS MEDICAL collection for those ... comfort of natural cotton fibers. , “When people step ... find socks as soft as the finest cashmere,” says Clay ...
(Date:9/2/2014)... 02, 2014 The exclusive ClinicCRM patient ... designed to help doctors manage foreign patient flow, enable ... conversion rates and clink revenue. Since its launch in ... in sales revenue and a 70 percent increase in ... their own healthcare practices. , With its ease of ...
(Date:9/2/2014)... of Experimental Biology and Medicine that ... biology and medicine of microphysiological systems" and describes ... Systems Program directed by the National Center for ... of Health (NIH) and funded in part by ... Projects Agency (DARPA) and the Food and Drug ...
Breaking Medicine News(10 mins):Health News:Booze, Pot Bad for Teens in Different Ways, Study Suggests 2Health News:SIGVARIS’ Luxury Line of Compression Socks, SEA ISLAND COTTON, Now Available in Stronger Compression Level 2Health News:Doctors Abroad Using VisitandCare.com Patient Management Software Report 60% Increase in Revenue 2Health News:Doctors Abroad Using VisitandCare.com Patient Management Software Report 60% Increase in Revenue 3Health News:Doctors Abroad Using VisitandCare.com Patient Management Software Report 60% Increase in Revenue 4Health News:Microphysiological systems will revolutionize experimental biology and medicine 2Health News:Microphysiological systems will revolutionize experimental biology and medicine 3
... , , , ... Sustained reduction of mitral regurgitation following mitral valve repair ... (DMR) or functional mitral regurgitation (FMR) led to heart function ... initial registry cohort of the EVEREST (Endovascular Valve Edge-to-Edge REpair ...
... , , , , ... over 2,000 motorcycle riders and enthusiasts will gather at Wisconsin Harley-Davidson ... "Ridin, to a Cure" fund raiser for breast cancer research in ... raise in excess of $300,000 over the weekend. The ride has ...
... , , One of Nation,s Best ... The health care network operated by the Department of Veterans Affairs (VA) has ... by the American Association of Retired Persons (AARP). , , "Quality ... Affairs Eric K. Shinseki. "VA is proud to be recognized as a top ...
... CHELMSFORD, Mass., Sept. 22 Magellan Biosciences, Inc. (Magellan), ... Life Sciences Tools (LST) business to Sunnyvale, California-based Dionex, Inc. ... ESA,s HPLC-related products, HPLC clinical assays, the ESA Laboratories services ... Financial terms of the transaction were not disclosed. , ...
... VA Physical therapist-directed exercise counseling combined with ... and exercise capacity in people with type 2 ... exercise, according to a randomized clinical trial published ... , the scientific journal of the American Physical ...
... Mo. About 2 million Americans currently use cocaine ... to making it one of the most dangerous and ... cause severe biological and behavioral problems, is very difficult ... and Sandeep Pendyam, doctoral students in the Department of ...
Cached Medicine News:Health News:MitraClip(R) Therapy Data Demonstrate Significant Left Ventricular Reverse Remodeling in Patients With Sustained Reduction of Mitral Regurgitation 2Health News:MitraClip(R) Therapy Data Demonstrate Significant Left Ventricular Reverse Remodeling in Patients With Sustained Reduction of Mitral Regurgitation 3Health News:We Need Your Support - 'Ridin' to a Cure' Sept. 25 and 26 2Health News:VA's Health System Top Employer for AARP 2Health News:Magellan Biosciences Sells its Life Sciences Tools Business to Dionex 2Health News:Magellan Biosciences Sells its Life Sciences Tools Business to Dionex 3Health News:People with type 2 diabetes improved muscular strength 2Health News:Computer model shows changes in brain mechanisms for cocaine addicts 2
(Date:9/2/2014)... 2014  Ameritox SM , the nation,s leader in ... Drugs to Heroin," a research report that provides concrete ... examines deadly trends that have created a unique heroin ... The report is based on data ... It examines five trends that distinguish the heroin abuse ...
(Date:9/2/2014)... , Spanje, September 2, 2014 ... GARFIELD AF Registry bij het ESC CONGRESS ... bij patiënten met risico op beroerte in ... Gegevens van bijna 12.500 patiënten ingeschreven ... FIELD-Atrial Fibrillation (GARFIELD-AF), een innovatief, onafhankelijk initiatief ...
(Date:9/2/2014)... 2014 Donald Spector , a renowned ... 8,823,512 for a Wearable Biosensor, which will issue today, ... this field.  Mr. Spector holds some of the earliest ... made today by New York College of Health Professions, ... of world-class intellectual properties.  New York College noted that ...
Breaking Medicine Technology:Ameritox Research Report Reveals Pain Patients' Role in Current Heroin Epidemic 2Gegevens uit wereldwijde atriumfibrillatieregister tonen aan dat antistollingsmiddelen niet optimaal worden gebruikt ter preventie van beroerte 2Gegevens uit wereldwijde atriumfibrillatieregister tonen aan dat antistollingsmiddelen niet optimaal worden gebruikt ter preventie van beroerte 3Gegevens uit wereldwijde atriumfibrillatieregister tonen aan dat antistollingsmiddelen niet optimaal worden gebruikt ter preventie van beroerte 4Gegevens uit wereldwijde atriumfibrillatieregister tonen aan dat antistollingsmiddelen niet optimaal worden gebruikt ter preventie van beroerte 5Gegevens uit wereldwijde atriumfibrillatieregister tonen aan dat antistollingsmiddelen niet optimaal worden gebruikt ter preventie van beroerte 6Gegevens uit wereldwijde atriumfibrillatieregister tonen aan dat antistollingsmiddelen niet optimaal worden gebruikt ter preventie van beroerte 7Gegevens uit wereldwijde atriumfibrillatieregister tonen aan dat antistollingsmiddelen niet optimaal worden gebruikt ter preventie van beroerte 8Gegevens uit wereldwijde atriumfibrillatieregister tonen aan dat antistollingsmiddelen niet optimaal worden gebruikt ter preventie van beroerte 9Gegevens uit wereldwijde atriumfibrillatieregister tonen aan dat antistollingsmiddelen niet optimaal worden gebruikt ter preventie van beroerte 10Wearable Biosensor Patent, the Grandfather of Wearable Biosensor Transmission Patents, Granted to Donald Spector, One of the Most Prolific Living Inventors in the World 2Wearable Biosensor Patent, the Grandfather of Wearable Biosensor Transmission Patents, Granted to Donald Spector, One of the Most Prolific Living Inventors in the World 3Wearable Biosensor Patent, the Grandfather of Wearable Biosensor Transmission Patents, Granted to Donald Spector, One of the Most Prolific Living Inventors in the World 4Wearable Biosensor Patent, the Grandfather of Wearable Biosensor Transmission Patents, Granted to Donald Spector, One of the Most Prolific Living Inventors in the World 5
... AMN Healthcare Services, Inc. (NYSE: AHS ), the largest ... quarterly conference call to discuss third quarter results on Thursday, ... also expects to issue an earnings news release on Thursday, ... 4:00 p.m. Eastern Time. , A live webcast of the ...
... CPhI Worldwide and connected events - the global pharma ingredients and ... - 15 October for its 20th staging. , The co-located ... technology events are joined for 2009 under the Where Pharma ... The new platform markedly reflects the notable convergence of the pharma ...
Cached Medicine Technology:AMN Healthcare Services to Host 2009 Third Quarter Earnings Conference Call on Thursday, October 29, 2009 2CPhI 2009: Madrid Launch for BioPh Marks Pharma and Biotech Convergence 2CPhI 2009: Madrid Launch for BioPh Marks Pharma and Biotech Convergence 3
Neomycin and Polymyxin B Sulfates and Hydrocortisone otic suspension, USP is a sterile antibacterial and anti-inflammatory suspension for otic use....
Prednisolone Acetate ophthalmic suspension USP, 1% is an adrenocortical steroid product prepared as a sterile ophthalmic suspension....
... A sophisticated research tool that allows ... area which is being stimulated. Besides it ... the examiner to switch between the pupil ... computer screen. This system is especially suited ...
The only air-based esthesiometer with a database of normal sensation on the cornea. May have application to the measurement of normal-tension glaucoma....
Medicine Products: