Navigation Links
Critical protein discovered for healthy cell growth in mammals
Date:1/27/2014

. "We didn't understand why, but now we do."

A cilium grows from a centriole, a structure that clings to the inner surface of the cell and serves as an anchor for the cilium. Before a cell can grow a cilium, it needs to assemble a set of appendages at one end of the centriole. These appendages can then connect the centriole to the cell surface, allowing the outgrowth of a cilium. Just how these appendages are assembled, though, remained a mystery for more than four decades since their discovery in 1962. Liu and his colleagues found that appendages were not assembled at the end of the centriole when the C2cd3 protein is not present. As a result, the centriole is not associated with the cell membrane and cannot recruit other proteins for the further growth of the cilium. "So our protein is required for the very first step of putting a cilium together," Liu explained. "Without those appendages, the cilium growth cannot happen."

The researchers hope their discovery will lead to greater knowledge of the process of cilium development and, eventually, to treatments for a wide range of health problems that fall under the label of ciliopathy. "Ciliopathy is a scientific term that covers a lot of diseases," Liu said. As well as contributing to cystic disorders in the kidney and liver, lack of cilia can lead to blindness or deafness, since cilia in the retina serve as receptors that process light stimulation and cilia within the ear are required in neurons that translate sound waves into neural signals.


'/>"/>

Contact: Barbara K. Kennedy
sciencew@psu.edu
814-863-4682
Penn State
Source:Eurekalert  

Page: 1 2

Related medicine news :

1. Need for Mosquito Control Becoming More Critical
2. Life Insurance To Cover Funeral Costs Or Critical Illness Plans? What Should Seniors Choose?
3. Is Critical Bench Program The Effective Solution For Building Muscle? – Vinamy
4. Critical Bench: Review Exposes Mike Westerdal’s Muscle and Strength Building Program
5. Middle East Critical Infrastructure Protection (CIP) Market (Technology, Solutions, Services) Worth $13.07 Billion by 2018 - New Report by MarketsandMarkets
6. Human neural stem cells could meet the clinical problem of critical limb ischemia
7. UC Irvine Health Appoints William C. Wilson, MD, as Director of Critical Care Services
8. Global Food Exchange Responds to Critical Need in the Philippines
9. UC Irvine Health Appoints William C. Wilson, MD, as Hospital Director of Critical Care Services, Division of the Department of Anesthesiology & Perioperative Care
10. Discover Innovative Upper Body Exercises With The “Critical Bench” Course – Vkoolelite
11. Critical Care Medicine Expert from The Children’s Hospital of Philadelphia Receives Distinguished Career Award
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Critical protein discovered for healthy cell growth in mammals
(Date:9/2/2015)... , ... September 02, 2015 , ... Ericson is a ... Education Director for HCPro and Associate Director of Education for the Association for Clinical ... CDI and ICD-10 for CDI Boot Camps. She serves as a CDI subject matter ...
(Date:9/2/2015)... ... ... Every year at this time, students prepare to go back to school. ... the academic workload confronting them. They just don’t have the skills needed to do ... students how to study. , “Bankers bank. Salesmen sell. Teachers teach. The job of ...
(Date:9/2/2015)... City, KS (PRWEB) , ... September 02, 2015 , ... ... opened its newest office in Kansas – its Johnson County location. Amada ... in healthcare. Mike has a registered nurse background and spent over 20 years in ...
(Date:9/2/2015)... North Las Vegas, NV (PRWEB) , ... September ... ... in Las Vegas and Fort Lauderdale, CENTURION SERVICE GROUP is internationally known as ... the largest medical auction house in the world, selling more than 100,000 pieces ...
(Date:9/2/2015)... ... 02, 2015 , ... On September 9, 2015, over 27,000 people from all ... single-company convention to date for the state of Utah. , “We are thrilled with ... states David Stirling, doTERRA CEO. “One of the most exciting elements of our convention ...
Breaking Medicine News(10 mins):Health News:ezDI Names Noted CDI Educator Cheryl Ericson as Company’s Clinical Documentation Manager 2Health News:ezDI Names Noted CDI Educator Cheryl Ericson as Company’s Clinical Documentation Manager 3Health News:ezDI Names Noted CDI Educator Cheryl Ericson as Company’s Clinical Documentation Manager 4Health News:5 Essential Study Tips Every Student Needs for Academic Success but Schools Do Not Teach 2Health News:5 Essential Study Tips Every Student Needs for Academic Success but Schools Do Not Teach 3Health News:Amada Senior Care Expands to Greater Kansas City 2Health News:Over 1800 Lots of Surplus Used Medical Equipment 2Health News:Over 1800 Lots of Surplus Used Medical Equipment 3Health News:doTERRA to Host the Largest Single-Company Convention in the State of Utah 2
... Dec. 1 The Kerlan Jobe Orthopaedic Clinic, a sports ... United States $3 million to settle allegations that it received ... , The settlement resolves allegations ... of stock option grants, donations to the Kerlan Jobe Foundation, ...
... A scientist who broadened the understanding of how we experience ... -- has won the 2010 University of Louisville Grawemeyer Award ... University in Montreal, was selected for the award from among ... of injury but instead in their brain through a pathway ...
... more likely, British study finds , TUESDAY, Dec. 1 (HealthDay ... to deliver a very preterm baby than more affluent women, ... British study shows. , The University of Leicester research team ... the association between economic status and preterm birth. , For ...
... on computed tomography (CT) imaging of changes in tumors ... bevacizumab may have the potential to predict overall survival, ... of JAMA . The addition of ... with improved survival in patients with stage IV colorectal ...
... ... ... largest national HIV non-profit organizations, is changing its name to HealthHIV and launching a new ... promote the organization’s new vision and expanded capabilities and reach. , , , , ,“HealthHIV ...
... With employee benefit choices becoming more complex, a growing ... during open enrollment season, according to a new survey by ... employers who offer these tools believe they lead employees to ... survey, 45 percent of companies offered employees self-service decision tools ...
Cached Medicine News:Health News:Los Angeles' Kerlan Jobe Orthopaedic Clinic Pays $3 Million to Settle Kickback Allegations 2Health News:Scientist Who Helps Explain Pain Wins Grawemeyer Award 2Health News:More Preemies Born Among the Poor 2Health News:Criteria based on CT imaging after chemotherapy may help predict survival 2Health News:National HIV Non-Profit Announces New Name 2Health News:Employers Plan to Increase Use of Self-Service Decision-Making Technology For Open Enrollment, Watson Wyatt Survey Finds 2Health News:Employers Plan to Increase Use of Self-Service Decision-Making Technology For Open Enrollment, Watson Wyatt Survey Finds 3
(Date:9/1/2015)... and BEDFORD, Mass. , ... Arroyo LLP is investigating whether certain officers ... Securities and Exchange Act of 1934.  ConforMIS is a ... platform to develop, manufacture, and sell joint replacement implants ... patient,s unique anatomy. View this press release ...
(Date:9/1/2015)... Delaware , United States ... "Company" or "Invion"), is pleased to announce that it has ... an institutional investor in the United States ... approximately A$1.001 million ("Placement") by the issue of 71,500,000 million ... per share. The Company has also agreed ...
(Date:9/1/2015)... and OR YEHUDA, Israel , Sept. ... HTWR ), a leading innovator of less invasive, ... of advanced heart failure, announced today that it has ... Cardio, Ltd . ("Valtech").  Valtech is a privately held ... and transcatheter valve repair and replacement devices for the ...
Breaking Medicine Technology:Robbins Arroyo LLP Is Investigating the Officers and Directors of ConforMIS, Inc. (CFMS) on Behalf of Shareholders 2Invion Announces Private Placement to US Institutional Investor 2Invion Announces Private Placement to US Institutional Investor 3HeartWare International Enters Into Definitive Agreement To Acquire Valtech Cardio, Ltd. 2HeartWare International Enters Into Definitive Agreement To Acquire Valtech Cardio, Ltd. 3HeartWare International Enters Into Definitive Agreement To Acquire Valtech Cardio, Ltd. 4HeartWare International Enters Into Definitive Agreement To Acquire Valtech Cardio, Ltd. 5HeartWare International Enters Into Definitive Agreement To Acquire Valtech Cardio, Ltd. 6HeartWare International Enters Into Definitive Agreement To Acquire Valtech Cardio, Ltd. 7HeartWare International Enters Into Definitive Agreement To Acquire Valtech Cardio, Ltd. 8HeartWare International Enters Into Definitive Agreement To Acquire Valtech Cardio, Ltd. 9HeartWare International Enters Into Definitive Agreement To Acquire Valtech Cardio, Ltd. 10
... 2011 Visionary Pharmaceuticals, Inc., announced today that ... a consortium of Angel Investors. The company is ... retinoic acid related orphan receptor (ROR) modulators targeting ... disorders including rheumatoid arthritis, multiple sclerosis, psoriasis and ...
... Ind., July 26, 2011 Symmetry Medical Inc. (NYSE: ... the global orthopaedic device industry and other medical markets, announced ... for the period ending July 2, 2011 before the market ... an accompanying conference call at 8:00 a.m. ET on Thursday, ...
Cached Medicine Technology:Visionary Pharmaceuticals, Inc., Announces Initial Seed Round Investments and the Launch of TH17 Autoimmune Disease Research Activities 2Symmetry Medical to Report Second Quarter 2011 Financial Results on August 4, 2011 2
SOLOS Endoscopy shares your commitment to provide every patient with the highest quality care available through our ongoing research and development of advanced surgical instruments and diagnostic so...
SOLOS Endoscopy shares your commitment to provide every patient with the highest quality care available through our ongoing research and development of advanced surgical instruments and diagnostic so...
... AEM Laparoscopic Instruments incorporate a layered design ... shielded and monitored to prevent stray electrosurgical ... caused by insulation failure or capacitive coupling; ... shield built into all AEM Instruments provides ...
... Instruments incorporate a layered design unique in ... monitored to prevent stray electrosurgical burns along ... insulation failure or capacitive coupling; a well-documented ... into all AEM Instruments provides a neutral ...
Medicine Products: