Navigation Links
'Crime Boss' Gene May Spur Breast Cancer
Date:3/12/2008

owing and dividing. And when they deliberately expressed the gene in the cancer cells, the tumors grew more aggressively, Kohwi-Shigematsu said.

The findings are published in the March 13 issue of Nature.

Dr. Len Lichtenfeld, deputy chief medical officer of the American Cancer Society, who is familiar with the new study, called it "elegant research."

"Basically what they have done is identify a protein that sets up a system that signals various genes within the cells to become abnormal," he said. "It is setting up an environment that allows multiple genes to become 'bad' genes at the same time."

While Kohwi-Shigematsu likened the SATB1 gene's activity to that of a crime "kingpin," Lichtenfeld said he think of it in terms of an orchestra conductor. Either way, genes get altered.

Lichtenfeld cautioned, however, that the finding is new and "a long way from clinical usage."

Kohwi-Shigematsu said her team next plans to study the gene's expression and its effects in people. "We don't know for sure that the cells that show SATB1 expression with the tumors are the ones that metastasize in a patient. But we think most likely that is the case."

If the research continues to bear fruit, the hope is that the presence of the gene's expressed protein will help doctors identify which breast cancers will spread, even in the disease's early stages.

Lichtenfeld added that the finding may also lead to new treatment options for breast cancer.

In another study, published in the March 12 issue of the Journal of the National Cancer Institute, researchers reported another genetic finding. People who carry a rare variant of the AKAP9 gene have a 10 percent increased relative risk of breast cancer in their lifetime if they have one copy of the variant. If they have two copies, the increased relative risk is 17 percent.

More information

To learn more about breast c
'/>"/>

Copyright©2008 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3

Related medicine news :

1. ViewPoint Bank Funds Senior Crimestoppers Program at Meadows Health and Rehab Center in Dallas
2. COX-2 expression is marker for cancer development in some benign breast biopsies
3. Late Use of Aromatase Inhibitor Still Effective Against Breast Cancer
4. Late treatment with letrozole can reduce breast cancer recurrence risk
5. Cardiac effects associated with breast cancer treatment appear lower with dose-dense chemotherapy
6. Yoga Eases Menopause Symptoms in Breast Cancer Survivors
7. Drugs like aspirin could reduce breast cancer and help existing sufferers
8. Estrogen Levels in Blood Predict Breast Cancers Return
9. The Pennsylvania Breast Cancer Coalition Announces Last Chance to Enter Makeover for Mom Contest
10. New revelations in epigenetic control shed light on breast cancer
11. UCSF researchers validate new model for breast cancer risk assessment in multiple ethnic groups
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
'Crime Boss' Gene May Spur Breast Cancer
(Date:11/22/2014)... November 22, 2014 Recently, UWDress.com is ... wedding guest dresses . In addition, the company has ... , As a leading online supplier of wedding ... beautiful outfits. The unusual best wedding guest gowns are ... the amazing designs, this new selection is famous for ...
(Date:11/22/2014)... Calif. (PRWEB) November 22, 2014 ... applications was announced today which safely detects and ... high frequency radio waves. Developed by RHT SpectraSafe, ... and hosts broad applications in other areas including ... to security. , Using high frequency radio waves ...
(Date:11/22/2014)... A Xarelto lawsuit has been filed on behalf ... million in damages from the makers and marketers of the ... the woman began using Xarelto in March 2012 and used ... she suffered life-threatening bleeding in July 2012 and as a ... emotional distress. The lawsuit purports that the woman’s injuries are ...
(Date:11/22/2014)... HealthDay Reporter FRIDAY, Nov. 21, ... are treated in an ambulance by a neurologist equipped with ... The sooner patients get the clot dissolver -- tissue plasminogen ... the researchers noted. For the best outcome, the drug needs ... start, the researchers said. "The so-called ,golden hour, is ...
(Date:11/21/2014)... November 21, 2014 Porcelain veneer ... smiles for patients in preparation for the coming holiday ... fronts of teeth, look completely natural, and can be ... veneers are also valued for their ability to strengthen ... can be used on one or several teeth to ...
Breaking Medicine News(10 mins):Health News:Best Wedding Guest dresses Introduced by UWDress.com 2Health News:RHT SpectraSafe announces a Radical New Airport Security Technology that Is More Effective, Less Invasive 2Health News:Xarelto Lawsuit News: Woman Seeks $10 Million in Damages For Alleged Bleeding Side-Effect Due To Xarelto Use 2Health News:Xarelto Lawsuit News: Woman Seeks $10 Million in Damages For Alleged Bleeding Side-Effect Due To Xarelto Use 3Health News:Xarelto Lawsuit News: Woman Seeks $10 Million in Damages For Alleged Bleeding Side-Effect Due To Xarelto Use 4Health News:Special Ambulance Delivers Vital Stroke Care More Quickly 2Health News:Special Ambulance Delivers Vital Stroke Care More Quickly 3Health News:Los Angeles Porcelain Veneers Dentist, Dr. Kevin Sands, Now Creates Picture-Perfect Smiles for Patients for the Holiday Season 2
... Inc. (Nasdaq: LMAT ) announced today that it ... 30, 2008, after the close of the,market. In conjunction ... same day at 5:00 PM ET. The call will ... listen to the live webcast at, http://www.lemaitre.com/investor, or ...
... 18 Dr. James B.,Peake, the Secretary of ... open a unique vocational counseling center for disabled,veterans., ... this center is yet,another partnership that recognizes the ... and access to resources to veterans sets,the stage ...
... BlueCross BlueShield of South,Carolina today announced that Greenville businesswoman ... A native of Elberton, Ga., Shaw now lives ... Corp., a family investment corporation.,She previously worked for C ... National,Bank of South Carolina, and Manly Investment Group in ...
... destination for quality skincare,will debut three new locations ... SEATTLE, April 18 Calidora Skin Clinic, ... its doors,in Southern California this April. The three ... Monica - will offer Southern Californians the,chance to ...
... been proved, one expert says , , FRIDAY, April 18 (HealthDay ... severe psoriasis appears to be safe and effective, a Canadian ... which is a calcineurin inhibitor, significantly improve symptoms of psoriasis. ... is the first oral medication in 20 years to show ...
... (OTC,Bulletin Board: CHRX, CHRXU, CHRXW), a leading provider of ... has,changed to CHRX from PMQC. The Company,s common stock ... About Chem Rx Corporation, Founded more than ... of institutional pharmacy services in the New York City,metropolitan ...
Cached Medicine News:Health News:Disabled Counseling Center Comes to Twin Cities 2Health News:Shaw Elected to S.C. BlueCross BlueShield Board 2Health News:Upscale Seattle-Based Skincare Clinic Expands Into California With Unique Custom Tailored Skincare Approach 2Health News:New Psoriasis Pill Appears Effective 2Health News:New Psoriasis Pill Appears Effective 3Health News:Chem Rx Corporation Changes Ticker Symbol to CHRX 2
(Date:11/21/2014)... 2014   Rock Creek Pharmaceuticals, Inc., (NASDAQ: ... scheduled to present at the Biotech Showcase™ 2015 taking ... on January 12-14, 2015. Michael ... Creek Pharmaceuticals, will present preclinical and clinical data for ... anti-inflammatory pharmacological characteristics. Dr. Mullan will outline the Company,s ...
(Date:11/21/2014)... , 21. November 2014 ... heute bekannt gegeben, dass die Europäische ... die Kennzeichnung als Orphan-Medizinprodukt an Palovarotene ... Unternehmens zur Behandlung von Fibrodysplasia ossificans ... stark beeinträchtigende genetische Krankheit, die von ...
(Date:11/21/2014)... N.J. , Nov. 20, 2014 /PRNewswire/-- CANTEL MEDICAL CORP. (NYSE: ... Krakauer , Chief Executive Officer, will be presenting at the ... New York Palace Hotel in New York ... 2014 at 2:00 PM ET. In addition, Mr. Krakauer and ... available for separate one-on-one meetings during the day. ...
Breaking Medicine Technology:Rock Creek Pharmaceuticals to Present at the Biotech Showcase 2015 2Rock Creek Pharmaceuticals to Present at the Biotech Showcase 2015 3Rock Creek Pharmaceuticals to Present at the Biotech Showcase 2015 4Clementia Pharmaceuticals erhält EMA-Kennzeichnung als Orphan-Medizin für Palovarotene zur Behandlung von Fibrodysplasia ossificans progressiva 2Clementia Pharmaceuticals erhält EMA-Kennzeichnung als Orphan-Medizin für Palovarotene zur Behandlung von Fibrodysplasia ossificans progressiva 3
... March 17, 2011 A recently issued patent ... award winning and best selling medical thermometer brand, ... recently been granted U.S. Patent No. 7,787,938, entitled, ... and Trademark Office, adding to the already extensive ...
... VEGAS, March 17, 2011 A new study by Craig ... and North Cypress Medical Center in Houston, presented this week ... the improved photon sensitivity of new detector technologies such as ... dose patient receive from BSGI/MBI studies by 75%.  However, low ...
Cached Medicine Technology:Exergen Granted New Patent for Temporal Artery Thermometers 2New Technologies Open the Door for Low Dose Breast-Specific Gamma Imaging (BSGI) / Molecular Breast Imaging (MBI) 2
SOLOS Endoscopy shares your commitment to provide every patient with the highest quality care available through our ongoing research and development of advanced surgical instruments and diagnostic so...
SOLOS Endoscopy shares your commitment to provide every patient with the highest quality care available through our ongoing research and development of advanced surgical instruments and diagnostic so...
... Instruments incorporate a layered design unique in ... monitored to prevent stray electrosurgical burns along ... insulation failure or capacitive coupling; a well-documented ... into all AEM Instruments provides a neutral ...
... The 5mm AEM Laparoscopic Instruments incorporate ... AEM Instruments are shielded and monitored to ... of the instrument caused by insulation failure ... risk. The protective shield built into all ...
Medicine Products: