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Cranial ultrasound may replace temporal artery biopsy in diagnosis of giant cell arteritis
Date:6/12/2014

combination of genetic and environmental factors, such as an infection may be responsible.2 Prompt treatment of GCA with high dose steroids is essential to prevent permanent loss of vision. In one study, 14% permanently lost vision because of GCA, and in 94% of these patients the visual deficit developed before steroid therapy for GCA was begun.3

In this study, all patients undergoing cranial ultrasound between January 2005 and July 2013 were identified and clinical data obtained from electronic records, and, if necessary primary care providers. ACR criteria for GCA were used to classify patients.

Ultrasound reports were independently classified according to whether there was evidence of an arteritis or not. Explicit ultrasound features of GCA, such as a halo sign were not required to make this determination. The relationship between the ACR criteria alone or in combination with ultrasound and a final clinical diagnosis of GCA (made after a minimum of three-month follow-up) was analysed. A clinical diagnosis of GCA after three months of follow up served as the gold standard. The sensitivity and specificity of cranial ultrasound and of TAB were examined against this gold standard.


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European League Against Rheumatism
Source:Eurekalert

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