Navigation Links
Could additives in hot dogs affect incidence of colon cancer?
Date:10/24/2011

BOSTON The addition of ascorbate (vitamin C) or its close relative, erythorbate, and the reduced amount of nitrite added in hot dogs, mandated in 1978, have been accompanied by a steep drop in the death rate from colon cancer, according to data presented at the 10th AACR International Conference on Frontiers in Cancer Prevention Research, held Oct. 22-25, 2011.

However, the incidence rate for colon cancer has apparently not changed much since 1978, according to 2011 data from the SEER Cancer Statistics Review from the National Cancer Institute.

"It was proposed that N-nitroso compounds in hot dogs and other processed meats can cause colon cancer," said Sidney S. Mirvish, Ph.D., professor emeritus at the Eppley Institute for Research in Cancer and Allied Diseases at the University of Nebraska Medical Center in Omaha. "We found that the level of total apparent N-nitroso compounds in hot dog links prepared in our laboratory fell as increasing levels of sodium erythorbate were included in the hot dog links."

Mirvish and colleagues discussed the view that colon cancer was induced by components of the apparent nonvolatile N-nitroso compounds that occur in processed (nitrite-preserved) meat. Hence, Mirvish and colleagues investigated the effect of varying the erythorbate level on the N-nitroso compound content of hot dogs.

They found that the current level of erythorbate (500 milligrams per kilogram) added to hot dogs reduces the N-nitroso compounds to 2 nanomoles per gram compared with 180 nanomoles per gram when erythorbate was not used.

"When erythorbate was not added, 80 percent of the apparent N-nitroso compounds were found to be due to nitrosothiols, which are probably harmless, still leaving 40 nanomoles per gram that were attributed to possibly carcinogenic N-nitroso compounds," Mirvish said.

If the level of N-nitroso compounds was an important cause of colon cancer, "the drop in N-nitroso compound co
'/>"/>

Contact: Jeremy Moore
Jeremy.Moore@aacr.org
267-646-0557
American Association for Cancer Research
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Could HPV Raise Womens Risk for Heart Disease?
2. Physical fitness could have a positive effect on eye health
3. Could Airway Abnormality Point to Autism?
4. Lasers precision and simplicity could revolutionize cataract surgery
5. 3 factors could point to your fate after surgery
6. UCSF study finds steroids could help heal some corneal ulcers
7. Expanding HIV treatment for discordant couples could significantly reduce global HIV epidemic
8. MRIs could become powerful tools for monitoring cholesteral therapy
9. Could Discrimination Help Trigger Illness in Blacks?
10. Permanently dismal economy could prompt men to seek more sex partners
11. Stem cells from cord blood could help repair damaged heart muscle
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/28/2014)... 2014 Lunadress.co.uk, one of the world’s ... has recently released its fashionable white prom gowns. These ... quality and low price. The company provides a big ... and free shipping for orders over 99 pounds. , ... professional sales representatives if needed. The kind experts will ...
(Date:11/28/2014)... 2014 The report “Poxvirus Infections ... the therapeutic development for Poxvirus Infections, complete with ... drug target, mechanism of action (MoA), route of ... updates, and featured news and press releases. It ... development for Poxvirus Infections and special features on ...
(Date:11/28/2014)... Angelweddingdress.com, a world-famous dress manufacturer and retailer, has ... Styles of Bridesmaid Dresses recently. A big ... free shipping on orders over $150! Those who ... less at the online store please click ... reliable dress supplier in the international market. It ...
(Date:11/28/2014)... Yesterday on November 27th, 2014, Thanksgiving morning, ... and families from 8 different sites throughout Miami-Dade and ... in Florida on Thanksgiving Day. Over 1,400 volunteers worked ... together individual meals via assembly lines and passing them ... includes turkey, stuffing, green beans, mashed potatoes, cranberry sauce, ...
(Date:11/28/2014)... 2014 Pathways Home Health & ... This national movement was created to encourage people to ... local charities and causes. This online event, celebrated ... kickoff of the holiday shopping season. #GivingTuesday is to ... Cyber Monday is to online commerce. , The goal ...
Breaking Medicine News(10 mins):Health News:LunaDress.co.uk: New White LunaDress Prom Gowns Online for Sale Now 2Health News:Poxvirus Infections and Vestibular Diseases Pipeline Market Drugs and Companies Review H2 2014 2Health News:Poxvirus Infections and Vestibular Diseases Pipeline Market Drugs and Companies Review H2 2014 3Health News:Poxvirus Infections and Vestibular Diseases Pipeline Market Drugs and Companies Review H2 2014 4Health News:Blue Color Styles of Bridesmaid Dresses from AngelWeddingDress.com are Available Now With Big Discounts 2Health News:Branches’ 14th Annual Thanksgiving Delivers 6,000+ Meals to Families in Need 2Health News:Pathways Home Health & Hospice Joins #GivingTuesday; Annual Holiday Encourages Local Charitable Giving 2Health News:Pathways Home Health & Hospice Joins #GivingTuesday; Annual Holiday Encourages Local Charitable Giving 3
... HealthDay Reporter , MONDAY, March 5 (HealthDay News) -- The more ... big screen, the more alcohol they drink themselves, a new study ... 10 to 19 from six European countries -- the largest study ... or more drinks on at least one occasion. Teens who ...
... , MONDAY, March 5 (HealthDay News) -- Babies ... greater risk of developing asthma when compared with children born ... to infants born between the 34th and 37th week of ... an asthma diagnosis by the age of 8 years, despite ...
... available in French . A ... increase in prevalence of Canadian children diagnosed with attention-deficit ... associated with ADHD in school-age children. The study, ... Among Canadian Preschoolers and School-Age Children: 1994-2007, was conducted ...
... study from Case Western Reserve University,s Frances Payne Bolton ... related to quality of life before becoming critically ill. ... a research team that observed, taped and analyzed discussions ... intensive care units (ICUs) at University Hospitals Case Medical ...
... gene that causes adult-onset primary cervical dystonia, an often-painful condition ... team from the Jacksonville, Fla., campus of Mayo Clinic and ... a movement disorder that physicians previously could seldom explain. Their ... . In 1990, a man with a crooked neck ...
... University of Notre Dame,s annual Bengal Bouts student boxing ... Bodies May Be Nourished." The unusual mantra is ... benefit Holy Cross Missions in Bangladesh, part of the ... Dame,s founding religious community. However, this year a large ...
Cached Medicine News:Health News:Drinking Scenes in Movies May Spur Teens to Do the Same 2Health News:Drinking Scenes in Movies May Spur Teens to Do the Same 3Health News:Late Preemie Birth May Be Linked to Higher Asthma Risk 2Health News:Hyperactivity: Increased prevalence of children with ADHD and the use of stimulants 2Health News:CWRU study finds quality-of-life discussions are important for ICU patients 2Health News:Researchers ID gene behind primary cervical dystonia, a neck-twisting disorder 2Health News:Researchers ID gene behind primary cervical dystonia, a neck-twisting disorder 3Health News:Notre Dame's Bengal Bouts participants aid in concussion research 2Health News:Notre Dame's Bengal Bouts participants aid in concussion research 3
(Date:11/26/2014)... VIEJO, Calif. , Nov. 26, 2014 /PRNewswire/ ... announced that the U.S. Food and Drug Administration ... its New Drug Application (NDA) for AVP-825. AVP-825 ... low-dose sumatriptan powder delivered intranasally utilizing a novel ... the Complete Response letter, and consistent with the ...
(Date:11/26/2014)... , November 26, 2014 Investor-Edge has ... VVUS ), Horizon Pharma PLC (NASDAQ: HZNP ... Johnson (NYSE: JNJ ), and Theravance Inc. (NASDAQ: ... can be accessed at: http://investor-edge.com/register . On ... up 0.07%, the Dow Jones Industrial Average edged 0.02% lower, ...
(Date:11/26/2014)... Nov. 26, 2014  BioScrip ® , Inc. (NASDAQ: ... and Chief Executive Officer, will present at the Bank of America ... , , Date: , , , Wednesday, December 3, 2014 ... EST , , , , Location: , , , Boca ... About BioScrip, Inc. BioScrip, Inc. is a ...
Breaking Medicine Technology:Avanir Pharmaceuticals Receives Complete Response Letter (CRL) from FDA on AVP-825 NDA 2Avanir Pharmaceuticals Receives Complete Response Letter (CRL) from FDA on AVP-825 NDA 3Avanir Pharmaceuticals Receives Complete Response Letter (CRL) from FDA on AVP-825 NDA 4Pharma Stocks Highlight - VIVUS, Horizon Pharma, Endocyte, Johnson and Johnson, and Theravance 2Pharma Stocks Highlight - VIVUS, Horizon Pharma, Endocyte, Johnson and Johnson, and Theravance 3Pharma Stocks Highlight - VIVUS, Horizon Pharma, Endocyte, Johnson and Johnson, and Theravance 4Pharma Stocks Highlight - VIVUS, Horizon Pharma, Endocyte, Johnson and Johnson, and Theravance 5
... Four novel genes that may,significantly increase the ... have been identified by researchers at Massachusetts General,Hospital ... November 7th issue,of American Journal of Human Genetics. ... (AGP) established three years ago to identify,the full ...
... FREMONT, Calif., Oct. 29 Vermillion, Inc.,(OTC Bulletin ... with Quest,Diagnostics to extend the Strategic Alliance Agreement ... enable the companies to continue,work on the development ... The OVA1 test is intended to identify women ...
Cached Medicine Technology:Breakthrough Mapping of Alzheimer's Genome Helps ID Four New Suspect Genes 2Breakthrough Mapping of Alzheimer's Genome Helps ID Four New Suspect Genes 3Vermillion Renews Strategic Alliance Agreement With Quest Diagnostics, Inc. 2Vermillion Renews Strategic Alliance Agreement With Quest Diagnostics, Inc. 3Vermillion Renews Strategic Alliance Agreement With Quest Diagnostics, Inc. 4
... This contact class is ... slit lamps which have a ... and the reduction prism than ... area: fundus / iridocornea. Mirror ...
... Fully Automatic High Speed Pre and Post ... a double-wall autoclave designed to cover a ... operating rooms, as well as private clinics ... designed for sterilization of medical and surgical ...
HRT II is the smallest scanning laser ever, light, portable and ready for telemedicine....
Subjective refraction unit, computer controlled and programmable. Two versions: with and without prisms....
Medicine Products: