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Could Statins Help Prevent Pneumonia?
Date:3/19/2012

By Steven Reinberg
HealthDay Reporter

MONDAY, March 19 (HealthDay News) -- Statin drugs, which are used to lower cholesterol, might reduce a bit the risk of developing pneumonia, a new study suggests.

Researchers analyzed data from a large international study that looked at the efficacy of rosuvastatin (Crestor) in preventing heart disease. The trial included almost 18,000 adults aged 50 or older who had no history of heart disease or diabetes. Participants were randomly selected to receive Crestor or an inactive placebo.

"These data from a major randomized trial support the hypothesis that statin treatment may be associated with a modest protective effect against some infections," said lead researcher Dr. Victor Novack, head of the Clinical Research Center at Soroka University Medical Center in Israel.

"We consider this analysis to be an additional step toward a definite trial that will specifically investigate the statin effect on infection," he said.

The researchers also found a decrease in some other types of infections such as soft tissue infections, gynecologic infections and fungal infections, Novack said.

In the past, statins such as Lipitor and others have been touted by some researchers for protecting brain function and lowering the risk for multiple sclerosis. However, they have also been linked to memory loss, depression and an increased risk for developing diabetes.

The new study was published March 19 in the CMAJ (Canadian Medical Association Journal).

Novack's group found that during roughly two years of follow-up, 214 of those taking the statin developed pneumonia, compared with 257 of those receiving the placebo.

While the study uncovered an association between statin use and a decrease in pneumonia, it did not prove a cause-and-effect relationship.

One problem with the finding may be that people taking statins take better care of themselves, the so-cal
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