Navigation Links
Could Alzheimer's disease be diagnosed with a simple blood test?
Date:1/25/2012

Spanish researchers, led by Pedro Carmona from the Instituto de Estructura de la Materia in Madrid, have uncovered a new promising way to diagnose Alzheimer's disease more accurately. Their technique, which is non-invasive, fast and low-cost, measures how much infrared radiation is either emitted or absorbed by white blood cells. Because of its high sensitivity, this method is able to distinguish between the different clinical stages of disease development thereby allowing reliable diagnosis of both mild and moderate stages of Alzheimer's. The work is published online in Springer's journal Analytical & Bioanalytical Chemistry.

Alzheimer's disease is the most common form of adult onset dementia and is characterized by the degeneration of the nervous system. In particular, as the disease progresses, the amount of amyloid- peptide in the body rises. At present, the most reliable and sensitive diagnostic techniques are invasive, e.g. require analysis of cerebrospinal fluid (the liquid that surrounds the brain and spinal cord). However, white blood cells (or mononuclear leukocytes) are also thought to carry amyloid- peptide in Alzheimer patients.

The researchers used two-dimensional infrared spectroscopy to measure and compare the infrared radiation emitted or absorbed by white blood cells of healthy controls, versus those of patients with mild, moderate and severe Alzheimer's disease. A total of 50 patients with Alzheimer's and 20 healthy controls took part in the study and gave blood samples.

The authors found significant differences in the range of infrared wavelengths displayed between subjects, which were attributable to the different stages of formation of amyloid- structures in the blood cells. The results showed that, with this method, healthy controls could be distinguished from mild and moderate sufferers of Alzheimer's disease. The method is being explored as a tool for early diagnosis.

The authors conclude: "The method we used can potentially offer a more simple detection of alternative biomarkers of Alzheimer's disease. Mononuclear leukocytes seem to offer a stable medium to determine -sheet structure levels as a function of disease development. Our measurements seem to be more sensitive for earlier stages of Alzheimer's disease, namely mild and moderate."


'/>"/>

Contact: Joan Robinson
joan.robinson@springer.com
49-622-148-78130
Springer
Source:Eurekalert

Related medicine news :

1. Could Magic Mushrooms Ease Depression?
2. Cocoa could prevent intestinal pathologies such as colon cancer
3. Going to physician visits with older loved ones could improve care
4. Heading Soccer Balls Could Injure Brain
5. Educating women about heart attacks could save lives
6. Could Internet Addiction Disrupt Brains Connections?
7. Omega-3 fatty acids could prevent and treat nerve damage, research suggests
8. Too Much Vitamin D Could Be Harmful to Heart
9. How many lives could a soda tax save?
10. Could Nicotine Patches Help Stave Off Memory Loss?
11. Could Daily Aspirin Harm Seniors Eyes?
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/24/2016)... ... ... New Jersey: This year marks Children’s Specialized Hospital ’s 125th anniversary of helping ... hospital has themed the milestone “Hats Off” and kicked off the yearlong celebration at ... 21, at Johnson Park in Piscataway, New Jersey. , “Hats Off” is ...
(Date:5/24/2016)... New York, NY (PRWEB) , ... May 24, ... ... of rehabilitative treatment for physical disease or injury that focuses on repairing the ... surgery. , With an emphasis on functional restoration, NYDNRehab began providing treatments ...
(Date:5/24/2016)... ... May 24, 2016 , ... Growing in popularity, more ... more gluten-free products are available and easily accessible. Whether someone chooses to cut gluten ... to a certain diet, King Kullen Grocery stocks their shelves with many different gluten-free ...
(Date:5/24/2016)... ... May 24, 2016 , ... ... a wellness specialist for forty years and a trainer for Ageless Grace ( ... Hour Radio Talk Show on May 16, 2016. , Formerly a Northwestern University ...
(Date:5/24/2016)... ... May 24, 2016 , ... ... Dominican Republic on September 21, 2016. Dr. Gerard, who holds a Doctorate of ... a not-for-profit organization promoting health and wellness in Third World countries where resources ...
Breaking Medicine News(10 mins):
(Date:5/24/2016)... 2016 Open Access Journal ... Elsevier , a world-leading provider of ... announced the launch of Clinical Neurophysiology ... focuses on clinical practice issues in clinical neurophysiology. The ... normal values and didactic reviews. It is an official ...
(Date:5/23/2016)... PUNE, India , May 23, 2016 ... is spread across 163 pages, profiles 12 companies and ... 280 tables and figures on the industry and its ... study that is comprehensive in nature, details the current ... of the industry including definitions, classifications, applications and industry ...
(Date:5/23/2016)... 23, 2016 Clarifying Vision - ... Monitoring, and Vision Care What can be ... going to grow at the fastest rates? This ... assessing data, trends, opportunities and prospects. ... Discover the most lucrative areas in the industry and ...
Breaking Medicine Technology: