Navigation Links
Could Alzheimer's disease be diagnosed with a simple blood test?
Date:1/25/2012

Spanish researchers, led by Pedro Carmona from the Instituto de Estructura de la Materia in Madrid, have uncovered a new promising way to diagnose Alzheimer's disease more accurately. Their technique, which is non-invasive, fast and low-cost, measures how much infrared radiation is either emitted or absorbed by white blood cells. Because of its high sensitivity, this method is able to distinguish between the different clinical stages of disease development thereby allowing reliable diagnosis of both mild and moderate stages of Alzheimer's. The work is published online in Springer's journal Analytical & Bioanalytical Chemistry.

Alzheimer's disease is the most common form of adult onset dementia and is characterized by the degeneration of the nervous system. In particular, as the disease progresses, the amount of amyloid- peptide in the body rises. At present, the most reliable and sensitive diagnostic techniques are invasive, e.g. require analysis of cerebrospinal fluid (the liquid that surrounds the brain and spinal cord). However, white blood cells (or mononuclear leukocytes) are also thought to carry amyloid- peptide in Alzheimer patients.

The researchers used two-dimensional infrared spectroscopy to measure and compare the infrared radiation emitted or absorbed by white blood cells of healthy controls, versus those of patients with mild, moderate and severe Alzheimer's disease. A total of 50 patients with Alzheimer's and 20 healthy controls took part in the study and gave blood samples.

The authors found significant differences in the range of infrared wavelengths displayed between subjects, which were attributable to the different stages of formation of amyloid- structures in the blood cells. The results showed that, with this method, healthy controls could be distinguished from mild and moderate sufferers of Alzheimer's disease. The method is being explored as a tool for early diagnosis.

The authors conclude: "The method we used can potentially offer a more simple detection of alternative biomarkers of Alzheimer's disease. Mononuclear leukocytes seem to offer a stable medium to determine -sheet structure levels as a function of disease development. Our measurements seem to be more sensitive for earlier stages of Alzheimer's disease, namely mild and moderate."


'/>"/>

Contact: Joan Robinson
joan.robinson@springer.com
49-622-148-78130
Springer
Source:Eurekalert

Related medicine news :

1. Could Magic Mushrooms Ease Depression?
2. Cocoa could prevent intestinal pathologies such as colon cancer
3. Going to physician visits with older loved ones could improve care
4. Heading Soccer Balls Could Injure Brain
5. Educating women about heart attacks could save lives
6. Could Internet Addiction Disrupt Brains Connections?
7. Omega-3 fatty acids could prevent and treat nerve damage, research suggests
8. Too Much Vitamin D Could Be Harmful to Heart
9. How many lives could a soda tax save?
10. Could Nicotine Patches Help Stave Off Memory Loss?
11. Could Daily Aspirin Harm Seniors Eyes?
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... Marcy was in a crisis. Her son ... lash out at his family verbally and physically. , “When something upset him, he couldn’t ... would use it. He would throw rocks at my other children and say he was ...
(Date:6/24/2016)... ... ... makers of Topricin and MyPainAway Pain Relief Products, join The ‘Business for a Fair Minimum ... by 2020 and then adjusting it yearly to increase at the same rate as the ... wage floor does not erode again, and make future increases more predictable. , The company ...
(Date:6/24/2016)... ... June 24, 2016 , ... Strategic Capital Partners, LLC ... by obtaining investment capital for emerging technology companies. SCP has delivered investment ... resulted in more than a million dollars of capital investment for five companies. ...
(Date:6/24/2016)... ... ... Finally, a bruise cream that really works. Originally designed to reduce ... post-surgical treatment plans of a variety of other procedures including, but not limited to, ... bruising and causes a rapid resolution of bruising and inflammatory changes compared to no ...
(Date:6/24/2016)... ... 2016 , ... Dr. Seema Daulat, a native Texan and University of Texas ... as of July 13, 2016. , Dr. Daulat earned her Doctorate of Medicine (MD) ... volunteered at the Agape Clinic serving Dallas’ underprivileged community. , Following medical school, Dr. ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... 2016 Bracket , a leading clinical trial ... clinical outcomes platform, Bracket eCOA (SM) 6.0, at the ... – 30, 2016 in Philadelphia , Pennsylvania.  ... Assessment product of its kind to fully integrate with RTSM, ... eCOA 6.0 is a flexible platform for electronic clinical outcomes ...
(Date:6/23/2016)... , June 23, 2016 Revolutionary ... Oticon , industry leaders in advanced audiology ... of Oticon Opn ™, the world,s first internet ... possibilities for IoT devices.      (Photo: ... introduces a number of ,world firsts,: , ...
(Date:6/23/2016)... Tenn. , June 23, 2016 /PRNewswire/ ... automating, integrating and transforming the patient payment ... of several innovative new products and services ... of its revenue cycle offerings. These award-winning ... more efficient workflows, remain compliant in an ...
Breaking Medicine Technology: