Navigation Links
Could Alzheimer's disease be diagnosed with a simple blood test?
Date:1/25/2012

Spanish researchers, led by Pedro Carmona from the Instituto de Estructura de la Materia in Madrid, have uncovered a new promising way to diagnose Alzheimer's disease more accurately. Their technique, which is non-invasive, fast and low-cost, measures how much infrared radiation is either emitted or absorbed by white blood cells. Because of its high sensitivity, this method is able to distinguish between the different clinical stages of disease development thereby allowing reliable diagnosis of both mild and moderate stages of Alzheimer's. The work is published online in Springer's journal Analytical & Bioanalytical Chemistry.

Alzheimer's disease is the most common form of adult onset dementia and is characterized by the degeneration of the nervous system. In particular, as the disease progresses, the amount of amyloid- peptide in the body rises. At present, the most reliable and sensitive diagnostic techniques are invasive, e.g. require analysis of cerebrospinal fluid (the liquid that surrounds the brain and spinal cord). However, white blood cells (or mononuclear leukocytes) are also thought to carry amyloid- peptide in Alzheimer patients.

The researchers used two-dimensional infrared spectroscopy to measure and compare the infrared radiation emitted or absorbed by white blood cells of healthy controls, versus those of patients with mild, moderate and severe Alzheimer's disease. A total of 50 patients with Alzheimer's and 20 healthy controls took part in the study and gave blood samples.

The authors found significant differences in the range of infrared wavelengths displayed between subjects, which were attributable to the different stages of formation of amyloid- structures in the blood cells. The results showed that, with this method, healthy controls could be distinguished from mild and moderate sufferers of Alzheimer's disease. The method is being explored as a tool for early diagnosis.

The authors conclude: "The method we used can potentially offer a more simple detection of alternative biomarkers of Alzheimer's disease. Mononuclear leukocytes seem to offer a stable medium to determine -sheet structure levels as a function of disease development. Our measurements seem to be more sensitive for earlier stages of Alzheimer's disease, namely mild and moderate."


'/>"/>

Contact: Joan Robinson
joan.robinson@springer.com
49-622-148-78130
Springer
Source:Eurekalert

Related medicine news :

1. Could Magic Mushrooms Ease Depression?
2. Cocoa could prevent intestinal pathologies such as colon cancer
3. Going to physician visits with older loved ones could improve care
4. Heading Soccer Balls Could Injure Brain
5. Educating women about heart attacks could save lives
6. Could Internet Addiction Disrupt Brains Connections?
7. Omega-3 fatty acids could prevent and treat nerve damage, research suggests
8. Too Much Vitamin D Could Be Harmful to Heart
9. How many lives could a soda tax save?
10. Could Nicotine Patches Help Stave Off Memory Loss?
11. Could Daily Aspirin Harm Seniors Eyes?
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/2/2016)... ... 2016 , ... The PAINWeekEnd Regional Conference will be hosted ... Honolulu, offering local frontline clinicians the opportunity to extend their certified continuing medical ... supplemental training related to pain management has surged dramatically in recent years, with ...
(Date:12/2/2016)... ... December 02, 2016 , ... Yisrayl Hawkins, at The ... how this current generation fits into Bible Prophecy. Yisrayl says this generation, known as ... to this conclusion, showing how the details line up exactly with Bible Prophecy – ...
(Date:12/2/2016)... PA (PRWEB) , ... December 02, 2016 , ... ... and pharmaceutical organizations to build intelligent, connected applications, was named the best Sales ... , The winner announcement was made today by the Software & Information ...
(Date:11/30/2016)... Northridge, CA (PRWEB) , ... November 30, 2016 ... ... Elyson, announce that they now offer a comprehensive in-house dental plan for all ... dentists have developed a plan that gives patients a number of perks, including ...
(Date:11/30/2016)... ... November 30, 2016 , ... Center ... has announced the opening of a new residential mental health treatment program in ... health issues such as severe anxiety, depression, bi-polar disorder, and other related issues. ...
Breaking Medicine News(10 mins):
(Date:12/2/2016)... 1, 2016  Today, Simpson Healthcare Executives, a global ... being selected as winners of multiple awards at the ... at the PLATINUM level, Blue Zones Menu at the ... GOLD Level, and our proprietary 3ConneX Platform at the ... Executives, we are excited to showcase our new Platinum ...
(Date:12/2/2016)... Dec. 2, 2016  UCB is pleased to announce that 12 ... upcoming 70 th American Epilepsy Society (AES) Annual Meeting, ... TX , USA. 1-12 Data ... profile of VIMPAT ® (lacosamide) CV and BRIVIACT ® ... on the current state of the union of epilepsy care ...
(Date:12/2/2016)... 2, 2016 Allergan plc (NYSE: AGN ... on its previously announced Accelerated Share Repurchase (ASR) Program. ... ... As previously announced, the Company entered into a variable ... Company will repurchase $10 billion of its ordinary shares. Approximately ...
Breaking Medicine Technology: