Navigation Links
Cough may warn of danger for patients with lung-scarring disease
Date:10/18/2011

A new analysis has found that coughing may signal trouble for patients with the lung-scarring disease known as idiopathic pulmonary fibrosis. The study, published in the journal Respirology, found that patients with the condition who also cough are more likely to develop advanced forms of the disease that may be life threatening.

When idiopathic pulmonary fibrosis develops, tissue deep in the lungs becomes thick and scarred, likely due to a response to an unknown substance. The condition affects approximately 100,000 individuals in the United States, and up to half die within three years of being diagnosed.

Almost all patients with idiopathic pulmonary fibrosis experience shortness of breath. The second most common symptom is cough. Shortness of breath is a known warning sign that a patient has a serious form of the disease, but little is known about the importance of cough.To investigate, Christopher Ryerson, MD, of the University of California, San Francisco, and his colleagues studied 242 patients with idiopathic pulmonary fibrosis. They found that cough was present in 84% of patients. It was more common in patients with advanced disease and in those who had never smoked. Also, the presence of cough predicted more rapid disease progression, regardless of the severity of a patient's disease. The study's findings indicate that the presence of cough may predict which patients are likely to die prematurely or need a lung transplant in the near future.

To investigate, Christopher Ryerson, MD, of the University of California, San Francisco, and his colleagues studied 242 patients with idiopathic pulmonary fibrosis. They found that cough was present in 84% of patients. It was more common in patients with advanced disease and in those who had never smoked. Also, the presence of cough predicted more rapid disease progression, regardless of the severity of a patient's disease. The study's findings indicate that the presence of cough may predict which patients are likely to die prematurely or need a lung transplant in the near future.

The authors concluded that patients with idiopathic pulmonary fibrosis who cough may have a worse prognosis compared with patients who do not cough. While additional studies are needed to validate the results, patients who cough may benefit from closer monitoring and more aggressive treatments.

"These findings improve our understanding of cough in idiopathic pulmonary fibrosis," said Dr. Ryerson. "The reason for the association between cough and never having smoked is unknown, but may provide insight into the pathogenesis of cough in idiopathic pulmonary fibrosis and thus prompt future research in this area," he added.


'/>"/>

Contact: Amy Molnar
healthnews@wiley.com
Wiley-Blackwell
Source:Eurekalert

Related medicine news :

1. TechWorld Medicals NasalCare Nasal Cleanse Kit Named “Best New Product” at ECRM Cough & Cold and Allergy Conference
2. New commentary suggests alternatives to routine use of OTC cold/cough meds in children
3. Commentary suggests alternatives to routine use of OTC cold/cough meds in children
4. Spread of Whooping Cough Raises Concern
5. Too Few Adults Vaccinated Against Whooping Cough: CDC
6. Cough medicine could help doctors identify how breast cancer patients metabolize tamoxifen
7. Cough Syrup Might Help With Dosing of Breast Cancer Drug
8. Parents Still Giving Cough, Cold Meds to Kids Under 2: Poll
9. FDA Bans Unapproved Prescription Cough, Cold and Allergy Meds
10. When you cough up green or yellow phlegm you need to be prescribed antibiotics, right?
11. Kids Hacking Is Seldom Whooping Cough, Study Finds
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/16/2017)... ... 2017 , ... To provide comfort and fuel during the ... category, announces a hearty and wholesome Winter Menu. Starting today, guests can enjoy ... Cranberry Crunch & Honey Parfait, Slow Cooked Smoky Chicken & Sausage Soup, and ...
(Date:1/16/2017)... (PRWEB) , ... January 16, 2017 , ... ... products, will demonstrate their groundbreaking GunSport•PRO® and EB15•LE® electronic earplugs at the NSSF ... in Las Vegas, Booth #2809. The SHOT Show is the shooting, hunting and ...
(Date:1/16/2017)... ... January 16, 2017 , ... ... announced the addition of Victor Giamos, MD to their medical staff, according to ... Partner at North Shore Eye Care, a division of SightMD. Dr. Giamos will ...
(Date:1/16/2017)... ... January 16, 2017 , ... St. Louisans are well-aware of the following facts at present:, ... year’s influenza shot seems to be having no effect on keeping this particularly bad strain ... the people around are coughing, sneezing, or sniffling , These facts are ...
(Date:1/16/2017)... ... 2017 , ... One thing common to all types of cancer is that ... well. The money spent screening for and treating cancer in the United States is ... cancer more than in any other country that has an advanced healthcare system, sometimes ...
Breaking Medicine News(10 mins):
(Date:1/16/2017)... Transparency Market Research states that the ...  held a huge share of 43% in 2015. Apple Inc., ... the overall market, grabbing the undivided attention of buyers with ... and strong product portfolio is expected to keep these companies ... ...
(Date:1/16/2017)... TORONTO , Jan. 16, 2017  Today, Analytics ... cost-effective medical devices, announced its expansion into JLABS @ ... Johnson Innovation,s life science incubators. As a resident in ... of cardiovascular medical device development and commercialization expertise. ... a life science innovation center that provides a flexible ...
(Date:1/15/2017)... January 16, 2017 Der Vorstand ... für die Regeneration des menschlichen Gewebes, gibt die Ernennung ... sofortiger Wirkung bekannt. ... Bill Allan ist ... bekleidete eine Reihe von Geschäftsführer- und anderen Führungspositionen bei ...
Breaking Medicine Technology: