Cost of Diabetes Care Has Doubled(nt in 1994 to 28 percent in 2007. Ano...),Health

Another factor fueling higher costs of diabetes care is that an increasing number of people are being diagnosed. In 2004, 4 percent of the U.S. population were diabetics; that number is expected to increase to 7 percent by 2050, the researchers said.

In addition, diabetic patients are receiving more aggressive treatment. Diabetic patients are often prescribed more than one medication. In 1994, 82 percent of diabetics received one drug; by 2007, only 47 percent of patients were receiving just one drug, the researchers found.

Alexander admitted that many of the new drugs target different pathways of disease. "There are some real innovations here," he said. "But we don't know enough about the comparative effectiveness of these medicines compared with older medicines to make a final verdict."

One of the concerns is that drugs are approved by the U.S. Food and Drug Administration before they have been tested on thousands of people, Alexander said. "All too often, physicians and patients may tend to adopt newer therapies without sufficient evidence of their superiority or benefits over older, less expensive, more time-tested alternatives," he said.

Recently, the diabetes drug Avandia has been linked to an increased risk for heart attack resulting in the FDA's adding a "black box" warning to the label.

Dr. Stuart Weiss, an endocrinologist at New York University Medical Center, thinks newer medications are more effective than the older ones, but they don't replace the need for a healthful diet and exercise.

"Spending money is bad, and diet and exercise is the best thing we can do for our diabetic patients, but they are not very comfortable accepting diet and exercise as the treatment for diabetes," Weiss said.

Using the older, generic medications is "good enough if your expectations are very low," Weiss said. Diabetes is a progressive disease, and drugs such as
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