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Cost-effectiveness of cetuximab in metastatic colorectal cancer
Date:8/7/2009

money by avoiding treatment for patients with KRAS mutations who do not respond to cetuximab, according to the editorialists. However, this study shows that even when restricted to metastatic colorectal cancer patients with wild-type KRAS tumors, the cost-per quality adjusted life year gained for cetuximab therapy compared to best supportive care exceeds commonly accepted thresholds of $50,000 to $100,000 per quality adjusted life year that signify "good value" health care interventions.

Given current attention to healthcare costs in the U.S., interest in explicitly comparing the costs and benefits of treatment, as performed by Mittmann et al. in Canada, is likely to increase. "The sustainability of the current approach to decision-making about coverage is unclear, particularly in light of escalating health care costs," the editorialists write.


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Contact: Steve Graff
jncimedia@oxfordjournals.org
301-841-1285
Journal of the National Cancer Institute
Source:Eurekalert

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